| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tomivosertib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tomivosertib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.217262 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.19142 |
| VIM | vimentin | 0.181083 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.082776 |
| FTL | ferritin, light polypeptide | 0.0798062 |
| CD44 | CD44 molecule (Indian blood group) | 0.0779021 |
| MT2A | metallothionein 2A | 0.0766068 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0745942 |
| B2M | beta-2-microglobulin | 0.0700686 |
| PCBP2 | poly(rC) binding protein 2 | 0.0637346 |
| TMSB10 | thymosin beta 10 | 0.0617265 |
| RPS6 | ribosomal protein S6 | 0.0615816 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0591499 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0587454 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0546668 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0539542 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0532723 |
| ANGPTL4 | angiopoietin-like 4 | 0.0530149 |
| RPS12 | ribosomal protein S12 | 0.0520669 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0517513 |
| PKM | pyruvate kinase, muscle | 0.0491099 |
| RPS8 | ribosomal protein S8 | 0.0483831 |
| LDHA | lactate dehydrogenase A | 0.0479883 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0465291 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0458457 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0451986 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.045072 |
| RPL37A | ribosomal protein L37a | 0.0440903 |
| CA12 | carbonic anhydrase XII | 0.0438066 |
| RPLP1 | ribosomal protein, large, P1 | 0.0437815 |
| IFI44L | interferon-induced protein 44-like | 0.0437065 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0434989 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0429109 |
| RPS19 | ribosomal protein S19 | 0.0427238 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0416484 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0409892 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0408129 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0404506 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0400826 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0400771 |
| NDRG1 | N-myc downstream regulated 1 | 0.0399434 |
| RPL31 | ribosomal protein L31 | 0.0378738 |
| STC1 | stanniocalcin 1 | 0.0360713 |
| LOXL2 | lysyl oxidase-like 2 | 0.035474 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0354695 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0351017 |
| ASPH | aspartate beta-hydroxylase | 0.0349279 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.034802 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0346662 |
| POTEF | POTE ankyrin domain family, member F | 0.0344925 |
| ECE1 | endothelin converting enzyme 1 | 0.0340618 |
| EGR1 | early growth response 1 | 0.0339822 |
| RPS17 | ribosomal protein S17 | 0.0336923 |
| EFNA5 | ephrin-A5 | 0.0326097 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0323238 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0322913 |
| AADAC | arylacetamide deacetylase | 0.0316741 |
| VEGFA | vascular endothelial growth factor A | 0.031626 |
| TGM2 | transglutaminase 2 | 0.0310046 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0307516 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0304897 |
| MYADM | myeloid-associated differentiation marker | 0.0304853 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0304287 |
| HMGA1 | high mobility group AT-hook 1 | 0.0302013 |
| RPL35A | ribosomal protein L35a | 0.0301556 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0301254 |
| RPL36 | ribosomal protein L36 | 0.0296933 |
| RACK1 | receptor for activated C kinase 1 | 0.0296083 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0294737 |
| RPL23 | ribosomal protein L23 | 0.0291766 |
| RPL37 | ribosomal protein L37 | 0.029134 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0282884 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0282845 |
| SP100 | SP100 nuclear antigen | 0.0281417 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0280822 |
| RPL32 | ribosomal protein L32 | 0.027792 |
| RPL11 | ribosomal protein L11 | 0.0274357 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0272977 |
| DTNA | dystrobrevin, alpha | 0.0270303 |
| S100A10 | S100 calcium binding protein A10 | 0.0269995 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0267196 |
| RPS3 | ribosomal protein S3 | 0.0266032 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0262432 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.025898 |
| MYO10 | myosin X | 0.0258788 |
| RPLP2 | ribosomal protein, large, P2 | 0.0255826 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0255124 |
| SQSTM1 | sequestosome 1 | 0.0253638 |
| PLIN2 | perilipin 2 | 0.0253629 |
| CDCP1 | CUB domain containing protein 1 | 0.0252101 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0251042 |
| ENO1 | enolase 1, (alpha) | 0.0251027 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0248747 |
| RPS27 | ribosomal protein S27 | 0.0246771 |
| RPS29 | ribosomal protein S29 | 0.0242356 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0242027 |
| RPL28 | ribosomal protein L28 | 0.0241352 |
| SMAD3 | SMAD family member 3 | 0.0238017 |
| PTK2 | protein tyrosine kinase 2 | 0.0229092 |
| FAM107B | family with sequence similarity 107, member B | 0.0227736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.109208 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105526 |
| RBM39 | RNA binding motif protein 39 | -0.0766944 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0590147 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0588177 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0524111 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0496079 |
| USP34 | ubiquitin specific peptidase 34 | -0.0409515 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0405888 |
| HDLBP | high density lipoprotein binding protein | -0.0379741 |
| LOX | lysyl oxidase | -0.0353432 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.03377 |
| FAM20C | family with sequence similarity 20, member C | -0.0336915 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.032391 |
| PRELID2 | PRELI domain containing 2 | -0.0317757 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0314673 |
| CANX | calnexin | -0.0314616 |
| OSMR | oncostatin M receptor | -0.0305007 |
| LRRC49 | leucine rich repeat containing 49 | -0.0301467 |
| AHNAK | AHNAK nucleoprotein | -0.0300536 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0300019 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0299169 |
| AOPEP | aminopeptidase O (putative) | -0.0296881 |
| GOLGA4 | golgin A4 | -0.0295401 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0291311 |
| ETV6 | ets variant 6 | -0.0289553 |
| GPC6 | glypican 6 | -0.0289508 |
| OGA | O-GlcNAcase | -0.0278849 |
| DST | dystonin | -0.0275326 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0274107 |
| FN1 | fibronectin 1 | -0.0272014 |
| SBF2 | SET binding factor 2 | -0.0266332 |
| OXSR1 | oxidative stress responsive 1 | -0.026456 |
| DENND4A | DENN/MADD domain containing 4A | -0.0261305 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0256459 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0255457 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0254922 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0252312 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0251865 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0251256 |
| MAP4 | microtubule-associated protein 4 | -0.0251228 |
| SYT1 | synaptotagmin I | -0.0251198 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0245483 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0241351 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0240885 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0238952 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.023838 |
| CD109 | CD109 molecule | -0.0237201 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0235985 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0234924 |
| GOLGA3 | golgin A3 | -0.0233841 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0233304 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0232686 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0229458 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0228366 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0228006 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0227082 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.022346 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0223107 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0222929 |
| CDH13 | cadherin 13 | -0.022247 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0220302 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0219632 |
| YEATS2 | YEATS domain containing 2 | -0.0219439 |
| CFDP1 | craniofacial development protein 1 | -0.0218476 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0216794 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0214492 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0214255 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0213162 |
| CEP95 | centrosomal protein 95kDa | -0.02122 |
| ZNF609 | zinc finger protein 609 | -0.0212148 |
| APP | amyloid beta (A4) precursor protein | -0.0208503 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0206917 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0205568 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0205323 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0205095 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0204525 |
| AAK1 | AP2 associated kinase 1 | -0.0204271 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0203296 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0200414 |
| NF1 | neurofibromin 1 | -0.0197398 |
| MYO9A | myosin IXA | -0.019665 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0195362 |
| GOLT1B | golgi transport 1B | -0.0194302 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0193996 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0193651 |
| NRP1 | neuropilin 1 | -0.0193309 |
| JMJD1C | jumonji domain containing 1C | -0.0192205 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0190963 |
| SETD5 | SET domain containing 5 | -0.01887 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0186733 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0186577 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0186524 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0186503 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0186124 |
| CDK13 | cyclin-dependent kinase 13 | -0.0184818 |
| SEC24D | SEC24 family member D | -0.0184795 |
| CLTC | clathrin, heavy chain (Hc) | -0.0184432 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.018253 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0182104 |
