| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tomivosertib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tomivosertib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0609253 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0476398 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0451022 |
| RPS6 | ribosomal protein S6 | 0.0445111 |
| RPS8 | ribosomal protein S8 | 0.0416048 |
| MKI67 | marker of proliferation Ki-67 | 0.0388017 |
| POTEF | POTE ankyrin domain family, member F | 0.0363765 |
| CENPF | centromere protein F, 350/400kDa | 0.0358369 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0347109 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0335524 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0299658 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0279306 |
| BMP10 | bone morphogenetic protein 10 | 0.0266418 |
| DIAPH3 | diaphanous-related formin 3 | 0.0248136 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0245289 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0237736 |
| GLI3 | GLI family zinc finger 3 | 0.02226 |
| RPS2 | ribosomal protein S2 | 0.0217726 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0211684 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0205403 |
| FER1L6 | fer-1-like family member 6 | 0.0203321 |
| RACK1 | receptor for activated C kinase 1 | 0.019612 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0195644 |
| HDAC9 | histone deacetylase 9 | 0.019115 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.018291 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0182784 |
| MACROD2 | MACRO domain containing 2 | 0.0171375 |
| RRM2 | ribonucleotide reductase M2 | 0.0170376 |
| CENPE | centromere protein E, 312kDa | 0.0169558 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0167949 |
| MYO5C | myosin VC | 0.0167881 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0166304 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0160285 |
| RPS12 | ribosomal protein S12 | 0.015753 |
| RPL31 | ribosomal protein L31 | 0.0156386 |
| FOXP1 | forkhead box P1 | 0.0155089 |
| NAV2 | neuron navigator 2 | 0.0151854 |
| TUBA1B | tubulin, alpha 1b | 0.0148127 |
| LDHB | lactate dehydrogenase B | 0.0147599 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0141553 |
| TPI1 | triosephosphate isomerase 1 | 0.0139115 |
| RPS17 | ribosomal protein S17 | 0.0137684 |
| ITGA10 | integrin, alpha 10 | 0.0136446 |
| AEBP2 | AE binding protein 2 | 0.0136139 |
| TPX2 | TPX2, microtubule-associated | 0.0132785 |
| KIF5C | kinesin family member 5C | 0.0131555 |
| INTS6 | integrator complex subunit 6 | 0.0130261 |
| PDE7B | phosphodiesterase 7B | 0.0129753 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0129466 |
| HJURP | Holliday junction recognition protein | 0.0127011 |
| PCNX4 | pecanex 4 | 0.0126415 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.0125691 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0125474 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0125407 |
| SEPTIN9 | septin 9 | 0.0125403 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0121554 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.0120655 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0117695 |
| MLIP | muscular LMNA-interacting protein | 0.0117174 |
| DUSP6 | dual specificity phosphatase 6 | 0.0116949 |
| STMN1 | stathmin 1 | 0.0113076 |
| CUX1 | cut-like homeobox 1 | 0.0112606 |
| BPTF | bromodomain PHD finger transcription factor | 0.011145 |
| BRD2 | bromodomain containing 2 | 0.0111366 |
| ASTN2 | astrotactin 2 | 0.0109576 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0109442 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0108165 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0108114 |
| KNL1 | kinetochore scaffold 1 | 0.0106729 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0106374 |
| CENPP | centromere protein P | 0.0106159 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0105044 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0104921 |
| MYADM | myeloid-associated differentiation marker | 0.0104231 |
| RPS27 | ribosomal protein S27 | 0.0103743 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0102858 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.0102751 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0102261 |
| CEP112 | centrosomal protein 112kDa | 0.0102083 |
| RPL37A | ribosomal protein L37a | 0.0101194 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0101044 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00999748 |
| IGF2 | insulin-like growth factor 2 | 0.00995947 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00991114 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.009909 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00980723 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.00977771 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.00969351 |
| FOXM1 | forkhead box M1 | 0.00952281 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.00951274 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00938208 |
| CREB5 | cAMP responsive element binding protein 5 | 0.00930502 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.00924846 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 | 0.00921044 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00916703 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.00916651 |
| CEP128 | centrosomal protein 128kDa | 0.00913423 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00913345 |
| HDGF | hepatoma-derived growth factor | 0.00909798 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.00904089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148861 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.108678 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.100119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0838921 |
| FLNB | filamin B, beta | -0.081246 |
| AHNAK | AHNAK nucleoprotein | -0.0806743 |
| RBM39 | RNA binding motif protein 39 | -0.074137 |
| GOLGA4 | golgin A4 | -0.0696741 |
| TMSB4X | thymosin beta 4, X-linked | -0.0693131 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0680017 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0656969 |
| RTN4 | reticulon 4 | -0.0654707 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0649694 |
| TXNRD1 | thioredoxin reductase 1 | -0.06238 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0504257 |
| ZNF292 | zinc finger protein 292 | -0.0494892 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0477476 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0463588 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0461124 |
| S100A6 | S100 calcium binding protein A6 | -0.045785 |
| ANK2 | ankyrin 2, neuronal | -0.0456431 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0444755 |
| PGK1 | phosphoglycerate kinase 1 | -0.0441272 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0435195 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0426661 |
| NBAS | neuroblastoma amplified sequence | -0.0423211 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0419931 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0414839 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.041389 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0413653 |
| ACTG1 | actin gamma 1 | -0.0396921 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0394042 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0391138 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0389963 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0388658 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0372487 |
| COG5 | component of oligomeric golgi complex 5 | -0.0370061 |
| NFIA | nuclear factor I/A | -0.0370061 |
| HDLBP | high density lipoprotein binding protein | -0.0364815 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.036221 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0358403 |
| PYGB | phosphorylase, glycogen; brain | -0.0354718 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0352763 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.035218 |
| NF1 | neurofibromin 1 | -0.0346572 |
| LDHA | lactate dehydrogenase A | -0.0335567 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0334273 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0333531 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0315344 |
| QKI | QKI, KH domain containing, RNA binding | -0.0315004 |
| SMYD3 | SET and MYND domain containing 3 | -0.0312369 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0310829 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0309371 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0308124 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0307432 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0305866 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305616 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0304618 |
| TMEM41B | transmembrane protein 41B | -0.0302751 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0298814 |
| USP3 | ubiquitin specific peptidase 3 | -0.0298629 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0297901 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0297099 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0289866 |
| MATR3 | matrin 3 | -0.0289269 |
| FBXO11 | F-box protein 11 | -0.0286948 |
| MSI2 | musashi RNA-binding protein 2 | -0.0286431 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0285204 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0283525 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0280682 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.027794 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.027599 |
| RHBDD1 | rhomboid domain containing 1 | -0.0275548 |
| NUP58 | nucleoporin 58 | -0.027277 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270794 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0269685 |
| YEATS2 | YEATS domain containing 2 | -0.0267431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267079 |
| SBF2 | SET binding factor 2 | -0.0264406 |
| GLI2 | GLI family zinc finger 2 | -0.0259511 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0259129 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0256307 |
| CDC73 | cell division cycle 73 | -0.0250378 |
| EVI5 | ecotropic viral integration site 5 | -0.0250376 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0249088 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0246478 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0246477 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.024596 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0245708 |
| TMEM65 | transmembrane protein 65 | -0.0245013 |
| MAP4 | microtubule-associated protein 4 | -0.0243231 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0242789 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0242658 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0242533 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.024241 |
| NBEA | neurobeachin | -0.0239621 |
| TFG | TRK-fused gene | -0.0238767 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0236927 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0234875 |
| RNF145 | ring finger protein 145 | -0.0233483 |
