| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tomivosertib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tomivosertib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0737585 |
| MT2A | metallothionein 2A | 0.0699573 |
| STC1 | stanniocalcin 1 | 0.0594559 |
| IL6 | interleukin 6 | 0.0503593 |
| MAP1B | microtubule-associated protein 1B | 0.0468634 |
| KYNU | kynureninase | 0.0392311 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0348257 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0346881 |
| CALD1 | caldesmon 1 | 0.0321912 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0321123 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0319846 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0312021 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0309992 |
| FAM13A | family with sequence similarity 13, member A | 0.0305403 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0288405 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0285645 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0278907 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0274336 |
| CD44 | CD44 molecule (Indian blood group) | 0.026506 |
| PRELID2 | PRELI domain containing 2 | 0.026158 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.025831 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0251235 |
| ARRDC3 | arrestin domain containing 3 | 0.0243985 |
| SMAD3 | SMAD family member 3 | 0.0243163 |
| TLN1 | talin 1 | 0.0242781 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0240352 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0235953 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0235952 |
| RNF24 | ring finger protein 24 | 0.0235921 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0216591 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0215144 |
| PTN | pleiotrophin | 0.0214851 |
| CBX3 | chromobox homolog 3 | 0.0211883 |
| FAT1 | FAT atypical cadherin 1 | 0.0209959 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0208649 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0206477 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0202464 |
| VEGFC | vascular endothelial growth factor C | 0.0198655 |
| LOXL2 | lysyl oxidase-like 2 | 0.019734 |
| MSN | moesin | 0.0197336 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.019496 |
| RSF1 | remodeling and spacing factor 1 | 0.0194387 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.019395 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0189359 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0189158 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0188751 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0183832 |
| ANO6 | anoctamin 6 | 0.0181286 |
| ATP13A3 | ATPase type 13A3 | 0.0177641 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0175831 |
| IL6ST | interleukin 6 signal transducer | 0.0171982 |
| NRP1 | neuropilin 1 | 0.0171114 |
| HIP1 | huntingtin interacting protein 1 | 0.0170623 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0168325 |
| RPS2 | ribosomal protein S2 | 0.0166352 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.016293 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0162141 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.016064 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0159108 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0158916 |
| TNS3 | tensin 3 | 0.0155509 |
| ZNF148 | zinc finger protein 148 | 0.015461 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0154264 |
| DST | dystonin | 0.0154117 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0152895 |
| AHR | aryl hydrocarbon receptor | 0.0151867 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0150234 |
| SERINC1 | serine incorporator 1 | 0.0150038 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0148522 |
| CCDC14 | coiled-coil domain containing 14 | 0.0146921 |
| FOSL1 | FOS-like antigen 1 | 0.0145548 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0145076 |
| TANK | TRAF family member-associated NFKB activator | 0.0143932 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0140316 |
| TMED4 | transmembrane emp24 protein transport domain containing 4 | 0.0139744 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0139269 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0138989 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0138587 |
| ZNF395 | zinc finger protein 395 | 0.0138492 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0134435 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0134259 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0133435 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0133368 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0132846 |
| C1S | complement component 1, s subcomponent | 0.0132242 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0131116 |
| RPLP0 | ribosomal protein, large, P0 | 0.0130788 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0130068 |
| INVS | inversin | 0.0130028 |
| RAI14 | retinoic acid induced 14 | 0.0129936 |
| SFXN1 | sideroflexin 1 | 0.0129813 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0129625 |
| ARSJ | arylsulfatase family, member J | 0.0128169 |
| RPS6 | ribosomal protein S6 | 0.0127729 |
| SYNJ2 | synaptojanin 2 | 0.0127703 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0127151 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.012715 |
| OPTN | optineurin | 0.0126972 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0126834 |
| GOLGA2 | golgin A2 | 0.0125953 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.169373 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.14124 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0972886 |
| PTMA | prothymosin, alpha | -0.077493 |
| NDRG1 | N-myc downstream regulated 1 | -0.0694361 |
| HLA-B | major histocompatibility complex, class I, B | -0.0604012 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0585098 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0580353 |
| TMSB10 | thymosin beta 10 | -0.0542127 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0470833 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0467281 |
| PGK1 | phosphoglycerate kinase 1 | -0.0439416 |
| VIM | vimentin | -0.0404377 |
| HLA-C | major histocompatibility complex, class I, C | -0.0379909 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0369587 |
| CALR | calreticulin | -0.0366045 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0357155 |
| RRBP1 | ribosome binding protein 1 | -0.0356559 |
| COL1A1 | collagen, type I, alpha 1 | -0.035574 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0348547 |
| FTL | ferritin, light polypeptide | -0.0334755 |
| CANX | calnexin | -0.0315621 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0305939 |
| RPL35A | ribosomal protein L35a | -0.0303653 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.030023 |
| RPS23 | ribosomal protein S23 | -0.0283832 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0281332 |
| ADM | adrenomedullin | -0.0279795 |
| ENO1 | enolase 1, (alpha) | -0.0274517 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0272522 |
| S100A10 | S100 calcium binding protein A10 | -0.0264115 |
| COL5A1 | collagen, type V, alpha 1 | -0.0255304 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0236156 |
| QKI | QKI, KH domain containing, RNA binding | -0.0236049 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0235602 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.023403 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0232063 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0229753 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0229433 |
| RBM39 | RNA binding motif protein 39 | -0.0228577 |
| RPL37 | ribosomal protein L37 | -0.0224885 |
| CDH13 | cadherin 13 | -0.0222062 |
| RPL34 | ribosomal protein L34 | -0.0221783 |
| FN1 | fibronectin 1 | -0.0220038 |
| TPM4 | tropomyosin 4 | -0.0219734 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.021868 |
| RPS13 | ribosomal protein S13 | -0.0215293 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0215048 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0214367 |
| GNAS | GNAS complex locus | -0.0212865 |
| HM13 | histocompatibility (minor) 13 | -0.0212356 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0208912 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0206434 |
| SEC24D | SEC24 family member D | -0.020248 |
| FBXO11 | F-box protein 11 | -0.0200732 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0200106 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0199653 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0197925 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0194661 |
| RPS15 | ribosomal protein S15 | -0.0194537 |
| RPLP1 | ribosomal protein, large, P1 | -0.0193685 |
| RPL27A | ribosomal protein L27a | -0.0193298 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0192936 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.019272 |
| RPS29 | ribosomal protein S29 | -0.0188216 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.018778 |
| TMEM41B | transmembrane protein 41B | -0.0185481 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0185374 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.018481 |
| GOLGA4 | golgin A4 | -0.0183053 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0182815 |
| TFG | TRK-fused gene | -0.0180505 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0178557 |
| LOX | lysyl oxidase | -0.0175934 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0173203 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0172595 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0170495 |
| LMNA | lamin A/C | -0.01703 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0168948 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0168444 |
| STC2 | stanniocalcin 2 | -0.0168104 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0167077 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0166726 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.016579 |
| SNX14 | sorting nexin 14 | -0.016434 |
| TFRC | transferrin receptor | -0.0163634 |
| RPLP2 | ribosomal protein, large, P2 | -0.0163083 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0162668 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0162257 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0160595 |
| VCP | valosin containing protein | -0.0158619 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0157563 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0156894 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0156778 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0155972 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0155638 |
| CTSD | cathepsin D | -0.0155604 |
| FAM20C | family with sequence similarity 20, member C | -0.0155359 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0152196 |
| S100A6 | S100 calcium binding protein A6 | -0.0150862 |
