| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tomivosertib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tomivosertib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.095113 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0906685 |
| NRG1 | neuregulin 1 | 0.0714403 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0632378 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0460326 |
| STC2 | stanniocalcin 2 | 0.0436366 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.041206 |
| RACK1 | receptor for activated C kinase 1 | 0.0408638 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0385937 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0369525 |
| FTL | ferritin, light polypeptide | 0.0361573 |
| INTS6 | integrator complex subunit 6 | 0.0358277 |
| PLIN2 | perilipin 2 | 0.0351516 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0350402 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0348537 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0336395 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0333633 |
| SQSTM1 | sequestosome 1 | 0.0325816 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0307364 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0292073 |
| RASAL2 | RAS protein activator like 2 | 0.02914 |
| VIM | vimentin | 0.0287945 |
| DSTN | destrin (actin depolymerizing factor) | 0.0265758 |
| RPL37A | ribosomal protein L37a | 0.026488 |
| RPS8 | ribosomal protein S8 | 0.0260137 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0255712 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0251724 |
| PALLD | palladin, cytoskeletal associated protein | 0.0251706 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0242052 |
| TMSB10 | thymosin beta 10 | 0.0237612 |
| DUSP6 | dual specificity phosphatase 6 | 0.0235567 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0233191 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0224756 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0224189 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0221996 |
| ENO1 | enolase 1, (alpha) | 0.0218292 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.021601 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0215092 |
| RPL31 | ribosomal protein L31 | 0.0214495 |
| HLA-A | major histocompatibility complex, class I, A | 0.0213474 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0212797 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0211592 |
| RPS12 | ribosomal protein S12 | 0.0208626 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0205118 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0195291 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0194942 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0191397 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0191322 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0187534 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0186107 |
| AEBP2 | AE binding protein 2 | 0.0185116 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0184389 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0181203 |
| LRRC23 | leucine rich repeat containing 23 | 0.0178064 |
| ACTG1 | actin gamma 1 | 0.0176817 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0176254 |
| TPI1 | triosephosphate isomerase 1 | 0.017271 |
| POTEF | POTE ankyrin domain family, member F | 0.0172342 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0171856 |
| IFI44L | interferon-induced protein 44-like | 0.0171355 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.016834 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0168252 |
| MYOF | myoferlin | 0.0167195 |
| JUN | jun proto-oncogene | 0.0165138 |
| B2M | beta-2-microglobulin | 0.0164696 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0164011 |
| NTN4 | netrin 4 | 0.0163902 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0163829 |
| RPS27 | ribosomal protein S27 | 0.016272 |
| RPS6 | ribosomal protein S6 | 0.0162252 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0161287 |
| BRD2 | bromodomain containing 2 | 0.0160753 |
| MYADM | myeloid-associated differentiation marker | 0.0158875 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0154782 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0150603 |
| ZFP36 | ZFP36 ring finger protein | 0.0150501 |
| HMGA2 | high mobility group AT-hook 2 | 0.0145201 |
| GPATCH2L | G patch domain containing 2-like | 0.0143225 |
| ABLIM1 | actin binding LIM protein 1 | 0.0143223 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0142615 |
| IL6 | interleukin 6 | 0.0142148 |
| UBAP2 | ubiquitin associated protein 2 | 0.0140143 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0140068 |
| RASEF | RAS and EF-hand domain containing | 0.0139938 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0138944 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0138255 |
| RPL9 | ribosomal protein L9 | 0.0138123 |
| NXN | nucleoredoxin | 0.0135965 |
| HLA-E | major histocompatibility complex, class I, E | 0.0135796 |
| HOMER1 | homer scaffolding protein 1 | 0.0135338 |
| POU2F2 | POU class 2 homeobox 2 | 0.0134997 |
| RPS17 | ribosomal protein S17 | 0.0134606 |
| MAP1B | microtubule-associated protein 1B | 0.0134235 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0133473 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0133024 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0132821 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0132728 |
| CCDC138 | coiled-coil domain containing 138 | 0.0132228 |
| RGS2 | regulator of G-protein signaling 2 | 0.013135 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0130126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.210901 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.141198 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.11092 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0889448 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0862284 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0778541 |
| CANX | calnexin | -0.0759557 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0728907 |
| RBM39 | RNA binding motif protein 39 | -0.0720231 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0707796 |
| CENPF | centromere protein F, 350/400kDa | -0.0676798 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0641896 |
| NDRG1 | N-myc downstream regulated 1 | -0.0640783 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0618093 |
| AHR | aryl hydrocarbon receptor | -0.0575392 |
| FN1 | fibronectin 1 | -0.0574581 |
| OSMR | oncostatin M receptor | -0.0569536 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0560196 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0537233 |
| OGA | O-GlcNAcase | -0.0536897 |
| SMOX | spermine oxidase | -0.0532782 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0532374 |
| CLTC | clathrin, heavy chain (Hc) | -0.0528498 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0527317 |
| NEK7 | NIMA-related kinase 7 | -0.0520136 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.051621 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0514907 |
| TXNIP | thioredoxin interacting protein | -0.0511339 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0505074 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0498606 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0487857 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0482801 |
| ETNK1 | ethanolamine kinase 1 | -0.0471738 |
| SMAD3 | SMAD family member 3 | -0.0464957 |
| SPAG9 | sperm associated antigen 9 | -0.0449715 |
| CD109 | CD109 molecule | -0.0448584 |
| SUCO | SUN domain containing ossification factor | -0.0446757 |
| MKI67 | marker of proliferation Ki-67 | -0.0440875 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.042517 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.041979 |
| TPR | translocated promoter region, nuclear basket protein | -0.0419012 |
| PTK2 | protein tyrosine kinase 2 | -0.0416078 |
| FNBP1 | formin binding protein 1 | -0.0413805 |
| ETV6 | ets variant 6 | -0.0410577 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.040804 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0399849 |
| ITGA1 | integrin, alpha 1 | -0.0399075 |
| ANLN | anillin, actin binding protein | -0.0398346 |
| ZNF292 | zinc finger protein 292 | -0.0398254 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0396394 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.039526 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0393413 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0390881 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0390182 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0390028 |
| RNF145 | ring finger protein 145 | -0.0385171 |
| TMEM165 | transmembrane protein 165 | -0.0383572 |
| TFG | TRK-fused gene | -0.0371391 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0370854 |
| GOLT1B | golgi transport 1B | -0.0369269 |
| RUNX2 | runt-related transcription factor 2 | -0.0367408 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0367164 |
| APP | amyloid beta (A4) precursor protein | -0.0364782 |
| NRP1 | neuropilin 1 | -0.0364459 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0363477 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0361578 |
| HELZ | helicase with zinc finger | -0.0360727 |
| IL6ST | interleukin 6 signal transducer | -0.0360231 |
| XPO1 | exportin 1 | -0.0355904 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0353981 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0353695 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0352128 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0350425 |
| NUP58 | nucleoporin 58 | -0.0350302 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0349466 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0347452 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0345793 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0344538 |
| PELO | pelota homolog (Drosophila) | -0.0342556 |
| WDR45B | WD repeat domain 45B | -0.0342421 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0342162 |
| COPA | coatomer protein complex, subunit alpha | -0.0341779 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0341672 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0336126 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0334601 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0333089 |
| CALU | calumenin | -0.0332034 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0331978 |
| CD44 | CD44 molecule (Indian blood group) | -0.0330443 |
| JMJD1C | jumonji domain containing 1C | -0.0329844 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0328721 |
| CDC73 | cell division cycle 73 | -0.0327145 |
| PTMA | prothymosin, alpha | -0.0326996 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0325506 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0321968 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0321883 |
| SMYD3 | SET and MYND domain containing 3 | -0.0321621 |
| DUSP5 | dual specificity phosphatase 5 | -0.0321 |
| COG5 | component of oligomeric golgi complex 5 | -0.0320971 |
| CAB39 | calcium binding protein 39 | -0.0316026 |
