Topiramate Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. (Chemical Entities of Biological Interest Ontology, CHEBI_63631)
External Link http://www.hmdb.ca/metabolites/HMDB05034
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Genes

6 interacting proteins for the Topiramate metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GRIK1 glutamate receptor, ionotropic, kainate 1
SCN1A sodium channel, voltage gated, type I alpha subunit