| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Torkinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Torkinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.251967 |
| LCN2 | lipocalin 2 | 0.180641 |
| EXT1 | exostosin glycosyltransferase 1 | 0.103065 |
| SMAD3 | SMAD family member 3 | 0.0993175 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0875184 |
| B2M | beta-2-microglobulin | 0.0866891 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0796706 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0738406 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0633204 |
| FTL | ferritin, light polypeptide | 0.0553614 |
| KYNU | kynureninase | 0.0535448 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0482669 |
| HKDC1 | hexokinase domain containing 1 | 0.0455566 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0439255 |
| POTEF | POTE ankyrin domain family, member F | 0.0417448 |
| LAMA4 | laminin, alpha 4 | 0.0416474 |
| ASPH | aspartate beta-hydroxylase | 0.039472 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0392041 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0390707 |
| SIK3 | SIK family kinase 3 | 0.0389131 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0388186 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.037851 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0372197 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0367227 |
| SQSTM1 | sequestosome 1 | 0.0364971 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0364598 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0351216 |
| DST | dystonin | 0.0336178 |
| FNIP2 | folliculin interacting protein 2 | 0.0332613 |
| AREG | amphiregulin | 0.0331402 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0324786 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316396 |
| RAB7A | RAB7A, member RAS oncogene family | 0.030815 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0302643 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0301146 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0299742 |
| RPLP0 | ribosomal protein, large, P0 | 0.029557 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0294857 |
| ATF4 | activating transcription factor 4 | 0.0288175 |
| PDZD8 | PDZ domain containing 8 | 0.0285479 |
| RPL35A | ribosomal protein L35a | 0.0281757 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0277607 |
| EFNB2 | ephrin-B2 | 0.0272327 |
| MYO1E | myosin IE | 0.0269546 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0263464 |
| TJP1 | tight junction protein 1 | 0.0263386 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.025853 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0255017 |
| RPS12 | ribosomal protein S12 | 0.0253256 |
| MYO5B | myosin VB | 0.0251896 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.025082 |
| KRT18 | keratin 18, type I | 0.024883 |
| MCU | mitochondrial calcium uniporter | 0.0245708 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0244975 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0243884 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0240935 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0239118 |
| TPI1 | triosephosphate isomerase 1 | 0.0238992 |
| PLIN2 | perilipin 2 | 0.0236319 |
| ACTG1 | actin gamma 1 | 0.023257 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0231468 |
| TMEM65 | transmembrane protein 65 | 0.0229329 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0227687 |
| RPL37A | ribosomal protein L37a | 0.0226578 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.022171 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0220363 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.02195 |
| SFTPA2 | surfactant protein A2 | 0.021932 |
| DIAPH1 | diaphanous-related formin 1 | 0.021899 |
| GK | glycerol kinase | 0.0218502 |
| MYOF | myoferlin | 0.021755 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0217068 |
| RPL31 | ribosomal protein L31 | 0.0216528 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0213336 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0212296 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0212126 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0212082 |
| S100P | S100 calcium binding protein P | 0.0211463 |
| RACK1 | receptor for activated C kinase 1 | 0.0209124 |
| CTSB | cathepsin B | 0.0204306 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.020284 |
| LAMB3 | laminin, beta 3 | 0.0201616 |
| MT2A | metallothionein 2A | 0.0200824 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0200811 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0199948 |
| RPL11 | ribosomal protein L11 | 0.0198568 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0195726 |
| SET | SET nuclear proto-oncogene | 0.0194979 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0191823 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0191074 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0189354 |
| DUSP10 | dual specificity phosphatase 10 | 0.018851 |
| ANXA1 | annexin A1 | 0.0188322 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0184421 |
| TRIM2 | tripartite motif containing 2 | 0.018381 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0181383 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0180873 |
| SLK | STE20-like kinase | 0.017961 |
| RPL7 | ribosomal protein L7 | 0.0178038 |
| ERBIN | erbb2 interacting protein | 0.0176273 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.121163 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.111923 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10337 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.101952 |
| TXNIP | thioredoxin interacting protein | -0.0879916 |
| NCKAP5 | NCK-associated protein 5 | -0.0876366 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0736766 |
| VCL | vinculin | -0.0705298 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0655499 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0642916 |
| EGR1 | early growth response 1 | -0.0638054 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.061436 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0613106 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0600918 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0600549 |
| RNF43 | ring finger protein 43 | -0.0587847 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.058058 |
| AHNAK | AHNAK nucleoprotein | -0.0577769 |
| JUN | jun proto-oncogene | -0.0532412 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0515759 |
| ACTN4 | actinin, alpha 4 | -0.051402 |
| STK24 | serine/threonine kinase 24 | -0.0512181 |
| H1-0 | H1.0 linker histone | -0.0484041 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0471144 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0464831 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0464647 |
| PRKCA | protein kinase C, alpha | -0.0458398 |
| TMEM62 | transmembrane protein 62 | -0.0457375 |
| RNF213 | ring finger protein 213 | -0.0454362 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0452882 |
| PKM | pyruvate kinase, muscle | -0.0446495 |
| PLSCR1 | phospholipid scramblase 1 | -0.0442233 |
| NDRG1 | N-myc downstream regulated 1 | -0.0433734 |
| MX1 | MX dynamin-like GTPase 1 | -0.0430747 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0424596 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0412271 |
| CCNL1 | cyclin L1 | -0.0410959 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0409882 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.039987 |
| PTEN | phosphatase and tensin homolog | -0.0392624 |
| VMP1 | vacuole membrane protein 1 | -0.0381165 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0374257 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0370412 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0367692 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0362415 |
| UBAC2 | UBA domain containing 2 | -0.0356837 |
| TNS4 | tensin 4 | -0.0356139 |
| MEIS2 | Meis homeobox 2 | -0.0351925 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0351746 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0347475 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0347163 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0344257 |
| TUFT1 | tuftelin 1 | -0.0342911 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0342836 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -0.034089 |
| MECOM | MDS1 and EVI1 complex locus | -0.0339858 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0335079 |
| RRBP1 | ribosome binding protein 1 | -0.0326274 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0322647 |
| AHI1 | Abelson helper integration site 1 | -0.0322525 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0321458 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0319707 |
| FOXP1 | forkhead box P1 | -0.0319344 |
| NPSR1 | neuropeptide S receptor 1 | -0.0316576 |
| SH3PXD2A | SH3 and PX domains 2A | -0.0315972 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0315294 |
| CANX | calnexin | -0.0314112 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0313555 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0310659 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0310544 |
| RBM39 | RNA binding motif protein 39 | -0.030693 |
| PRELID2 | PRELI domain containing 2 | -0.0305636 |
| SSH2 | slingshot protein phosphatase 2 | -0.0300605 |
| RAD51B | RAD51 paralog B | -0.0300428 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.029854 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0293979 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0292686 |
| NF1 | neurofibromin 1 | -0.0290948 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0290904 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0289554 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0286629 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0285836 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0284388 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0283901 |
| RBM26 | RNA binding motif protein 26 | -0.0282412 |
| RIGI | RNA sensor RIG-I | -0.0280654 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0280221 |
| DGKH | diacylglycerol kinase, eta | -0.0277665 |
| HBS1L | HBS1-like translational GTPase | -0.0275248 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0274131 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0272871 |
| ZNF207 | zinc finger protein 207 | -0.0272039 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0271481 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0271221 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0270211 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0265794 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0262293 |
| DIAPH3 | diaphanous-related formin 3 | -0.0261856 |
| GNAS | GNAS complex locus | -0.02606 |
| SPPL3 | signal peptide peptidase like 3 | -0.025499 |
