| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Torkinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Torkinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.0931908 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0903668 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0876414 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0866349 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0813848 |
| CD44 | CD44 molecule (Indian blood group) | 0.0757646 |
| FAM20C | family with sequence similarity 20, member C | 0.0692433 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0643699 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0628309 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0619257 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0601269 |
| HMGA2 | high mobility group AT-hook 2 | 0.0576893 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0576512 |
| FNDC3B | fibronectin type III domain containing 3B | 0.052752 |
| IFI44L | interferon-induced protein 44-like | 0.0509763 |
| ASPH | aspartate beta-hydroxylase | 0.0495436 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0484609 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0477762 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.04508 |
| NAV2 | neuron navigator 2 | 0.0434348 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0432813 |
| EXT1 | exostosin glycosyltransferase 1 | 0.043008 |
| CA12 | carbonic anhydrase XII | 0.0425932 |
| MTSS1 | metastasis suppressor 1 | 0.0420695 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0413713 |
| ATXN1 | ataxin 1 | 0.0411025 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0397449 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.039641 |
| SMAD3 | SMAD family member 3 | 0.0396158 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0395459 |
| SEPTIN9 | septin 9 | 0.0390557 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0389788 |
| MYO10 | myosin X | 0.0381464 |
| ANGPTL4 | angiopoietin-like 4 | 0.0378331 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0376921 |
| DST | dystonin | 0.0375235 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0374564 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0365293 |
| ENO1 | enolase 1, (alpha) | 0.0359719 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0357511 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0353548 |
| INTS6 | integrator complex subunit 6 | 0.0346155 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0341656 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0341526 |
| SQSTM1 | sequestosome 1 | 0.0341046 |
| AADAC | arylacetamide deacetylase | 0.0338339 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.033668 |
| FN1 | fibronectin 1 | 0.0329884 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0325969 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0325763 |
| NRG1 | neuregulin 1 | 0.0318425 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.031429 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0303598 |
| TGM2 | transglutaminase 2 | 0.0301183 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0295781 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.029375 |
| RNF213 | ring finger protein 213 | 0.0293636 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0289097 |
| CDH13 | cadherin 13 | 0.0287081 |
| CDCP1 | CUB domain containing protein 1 | 0.0280631 |
| LOX | lysyl oxidase | 0.0280385 |
| B2M | beta-2-microglobulin | 0.0275685 |
| LOXL2 | lysyl oxidase-like 2 | 0.0275466 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0275065 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.027217 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0270324 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0263789 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0262319 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0261103 |
| RAD51B | RAD51 paralog B | 0.0257766 |
| GLIS3 | GLIS family zinc finger 3 | 0.0257401 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0253408 |
| NAV1 | neuron navigator 1 | 0.0250445 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0247747 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0244884 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0231942 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0230296 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.022787 |
| POTEF | POTE ankyrin domain family, member F | 0.0225286 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0225253 |
| NOTCH2 | notch 2 | 0.0222826 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0221815 |
| PLIN2 | perilipin 2 | 0.021636 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0215995 |
| PRKCA | protein kinase C, alpha | 0.0215025 |
| EGFR | epidermal growth factor receptor | 0.0214069 |
| MX1 | MX dynamin-like GTPase 1 | 0.0212728 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0211624 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0207417 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203363 |
| TGFB1 | transforming growth factor, beta 1 | 0.0202598 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0201772 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0201466 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0199492 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0197509 |
| WWOX | WW domain containing oxidoreductase | 0.0196677 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0195772 |
| EHBP1 | EH domain binding protein 1 | 0.0195616 |
| SVIL | supervillin | 0.0195105 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0193252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.191534 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.179658 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.13841 |
| GOLGA4 | golgin A4 | -0.124346 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107718 |
| RBM39 | RNA binding motif protein 39 | -0.0902386 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0841697 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.080035 |
| TMSB10 | thymosin beta 10 | -0.0765888 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0700084 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0590153 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0580367 |
| FTL | ferritin, light polypeptide | -0.0564217 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0515017 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0510432 |
| SRP54 | signal recognition particle 54kDa | -0.0488079 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0482661 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0468503 |
| COG5 | component of oligomeric golgi complex 5 | -0.0462288 |
| OGA | O-GlcNAcase | -0.0460498 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0455399 |
| PTMA | prothymosin, alpha | -0.0450195 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0449995 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0447083 |
| CANX | calnexin | -0.0443196 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0431519 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0419205 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0414542 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0413383 |
| WDR45B | WD repeat domain 45B | -0.0410705 |
| SETD5 | SET domain containing 5 | -0.0408709 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0402467 |
| USP3 | ubiquitin specific peptidase 3 | -0.0399069 |
| GLCCI1 | glucocorticoid induced 1 | -0.0387705 |
| RIOK3 | RIO kinase 3 | -0.0387532 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0387023 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0386527 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0385547 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0382195 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0379513 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0379016 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0369889 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0368651 |
| YME1L1 | YME1-like 1 ATPase | -0.036852 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0366299 |
| SPAG9 | sperm associated antigen 9 | -0.0364464 |
| COPA | coatomer protein complex, subunit alpha | -0.0361509 |
| SBF2 | SET binding factor 2 | -0.0359271 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0357731 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0356389 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0336085 |
| FAM13A | family with sequence similarity 13, member A | -0.0332649 |
| ZNF292 | zinc finger protein 292 | -0.0330445 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0328234 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0326554 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0318853 |
| OXSR1 | oxidative stress responsive 1 | -0.0318682 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.031672 |
| MORF4L2 | mortality factor 4 like 2 | -0.0316311 |
| GLG1 | golgi glycoprotein 1 | -0.0314196 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0314019 |
| WASF2 | WAS protein family, member 2 | -0.0313507 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0310877 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0304169 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0303761 |
| SUCO | SUN domain containing ossification factor | -0.0302448 |
| TMEM263 | transmembrane protein 263 | -0.0301496 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0299841 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0298076 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0295559 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0293756 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0293302 |
| RNF145 | ring finger protein 145 | -0.0291812 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0291665 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0290794 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0289371 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0283588 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0282952 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0282609 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0281074 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0281036 |
| JMJD1C | jumonji domain containing 1C | -0.0279834 |
| IER3 | immediate early response 3 | -0.0279429 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0279403 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0274961 |
| YBX3 | Y box binding protein 3 | -0.0273908 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0272723 |
| USP34 | ubiquitin specific peptidase 34 | -0.0272715 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0272707 |
| CALR | calreticulin | -0.0271201 |
| RNF24 | ring finger protein 24 | -0.0270533 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0269293 |
| OSMR | oncostatin M receptor | -0.0268503 |
| TPR | translocated promoter region, nuclear basket protein | -0.0267995 |
| NF1 | neurofibromin 1 | -0.0267971 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0267434 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0267323 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0257803 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0253086 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0251339 |
