| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Torkinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Torkinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.1578 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.13471 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.120656 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.100424 |
| EZR | ezrin | 0.0964748 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0920139 |
| ENO1 | enolase 1, (alpha) | 0.0751983 |
| HDAC9 | histone deacetylase 9 | 0.066801 |
| POTEF | POTE ankyrin domain family, member F | 0.0665202 |
| ANXA1 | annexin A1 | 0.064437 |
| ZNF608 | zinc finger protein 608 | 0.0639185 |
| RPS12 | ribosomal protein S12 | 0.0608822 |
| BMP10 | bone morphogenetic protein 10 | 0.0597486 |
| RPL37A | ribosomal protein L37a | 0.0465663 |
| CREB5 | cAMP responsive element binding protein 5 | 0.044756 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0439928 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0435282 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0406675 |
| MYOF | myoferlin | 0.0401649 |
| RPL3 | ribosomal protein L3 | 0.0391369 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0387669 |
| FER1L6 | fer-1-like family member 6 | 0.0386764 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0384718 |
| RPS8 | ribosomal protein S8 | 0.0367207 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0365462 |
| PDGFC | platelet derived growth factor C | 0.0357211 |
| MKI67 | marker of proliferation Ki-67 | 0.0346912 |
| MACROD2 | MACRO domain containing 2 | 0.0341658 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0331057 |
| RPL31 | ribosomal protein L31 | 0.0318127 |
| SGMS2 | sphingomyelin synthase 2 | 0.031784 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0315214 |
| RPS3 | ribosomal protein S3 | 0.0310207 |
| TMSB10 | thymosin beta 10 | 0.0306648 |
| TPM3 | tropomyosin 3 | 0.0306387 |
| FN1 | fibronectin 1 | 0.0305413 |
| PCBP2 | poly(rC) binding protein 2 | 0.0301546 |
| FAT1 | FAT atypical cadherin 1 | 0.0294579 |
| KIF5B | kinesin family member 5B | 0.0291678 |
| RPS17 | ribosomal protein S17 | 0.029038 |
| MYO5C | myosin VC | 0.0289443 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0289427 |
| SIK3 | SIK family kinase 3 | 0.0288919 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0285678 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0284295 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0278981 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0278888 |
| VIM | vimentin | 0.0275597 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0274211 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0273013 |
| TPM4 | tropomyosin 4 | 0.0271979 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0264752 |
| RRM2 | ribonucleotide reductase M2 | 0.0264504 |
| ANLN | anillin, actin binding protein | 0.0263793 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0261219 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0254581 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0251012 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0250475 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247735 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0245679 |
| BMP2K | BMP2 inducible kinase | 0.0241054 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0239524 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0238409 |
| SETX | senataxin | 0.0237302 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0235265 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0234095 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0232484 |
| RPS27A | ribosomal protein S27a | 0.0232247 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.023163 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0231259 |
| SEPTIN9 | septin 9 | 0.0229442 |
| USP47 | ubiquitin specific peptidase 47 | 0.0227399 |
| HMGA2 | high mobility group AT-hook 2 | 0.0224575 |
| IGF2 | insulin-like growth factor 2 | 0.0224383 |
| RPL9 | ribosomal protein L9 | 0.0221695 |
| SON | SON DNA binding protein | 0.0221302 |
| CCDC88A | coiled-coil domain containing 88A | 0.0218669 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0217886 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0216807 |
| RACK1 | receptor for activated C kinase 1 | 0.0215584 |
| RPL27 | ribosomal protein L27 | 0.021543 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0213123 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0212374 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0210356 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0209572 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0207262 |
| RPS27 | ribosomal protein S27 | 0.0206739 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0206616 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0206284 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0206039 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0205082 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.020178 |
| NDRG1 | N-myc downstream regulated 1 | 0.0201199 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0200987 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0200372 |
| ASPH | aspartate beta-hydroxylase | 0.0199674 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0198508 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0197776 |
| INTS6 | integrator complex subunit 6 | 0.0197475 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0197314 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.271202 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149621 |
| PTMA | prothymosin, alpha | -0.112983 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10097 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.094988 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0941244 |
| S100A6 | S100 calcium binding protein A6 | -0.0828944 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0724011 |
| ANK2 | ankyrin 2, neuronal | -0.0679582 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.059653 |
| TXNRD1 | thioredoxin reductase 1 | -0.0568276 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0527171 |
| VCL | vinculin | -0.0518302 |
| TMSB4X | thymosin beta 4, X-linked | -0.0518092 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0517247 |
| NFIA | nuclear factor I/A | -0.0510361 |
| ZNF292 | zinc finger protein 292 | -0.0507163 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0507042 |
| RBM39 | RNA binding motif protein 39 | -0.0502126 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0501299 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0495336 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0493944 |
| ANKRD11 | ankyrin repeat domain 11 | -0.049185 |
| GOLGA4 | golgin A4 | -0.0478496 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0474082 |
| EGFR | epidermal growth factor receptor | -0.0464397 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0451734 |
| RTN4 | reticulon 4 | -0.0447791 |
| AHNAK | AHNAK nucleoprotein | -0.0441942 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0440121 |
| OSMR | oncostatin M receptor | -0.0436302 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0428366 |
| HDLBP | high density lipoprotein binding protein | -0.0415166 |
| TMEM41B | transmembrane protein 41B | -0.0414533 |
| GLI2 | GLI family zinc finger 2 | -0.0414497 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0401589 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0390548 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0387673 |
| ACTG1 | actin gamma 1 | -0.0385352 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0375786 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0374459 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0372877 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.037196 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0371525 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0360504 |
| CCND1 | cyclin D1 | -0.0359821 |
| TRERF1 | transcriptional regulating factor 1 | -0.0359113 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0347646 |
| SETD5 | SET domain containing 5 | -0.034331 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0342825 |
| LDHA | lactate dehydrogenase A | -0.033715 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0336226 |
| NF1 | neurofibromin 1 | -0.0335549 |
| EVI5 | ecotropic viral integration site 5 | -0.0329946 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0328715 |
| PHF14 | PHD finger protein 14 | -0.0326807 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0324404 |
| MAP4 | microtubule-associated protein 4 | -0.0323162 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0318611 |
| TMEM263 | transmembrane protein 263 | -0.0315985 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0312307 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0312039 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0310344 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0308994 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0308459 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0301888 |
| FBXO11 | F-box protein 11 | -0.0300739 |
| COG5 | component of oligomeric golgi complex 5 | -0.0300075 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0296323 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0292119 |
| COPA | coatomer protein complex, subunit alpha | -0.0292061 |
| RNF145 | ring finger protein 145 | -0.0286713 |
| PTEN | phosphatase and tensin homolog | -0.0286019 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0285928 |
| CCNI | cyclin I | -0.0284932 |
| AHI1 | Abelson helper integration site 1 | -0.0281867 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0281693 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0280862 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0279441 |
| FNBP4 | formin binding protein 4 | -0.0279414 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0278311 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0275561 |
| WDR45B | WD repeat domain 45B | -0.027378 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0273663 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0271047 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0266127 |
| EXOC6B | exocyst complex component 6B | -0.0264122 |
| ZNF248 | zinc finger protein 248 | -0.0264068 |
| RRBP1 | ribosome binding protein 1 | -0.0263886 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0262391 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0260523 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0256574 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0255964 |
| TCF12 | transcription factor 12 | -0.0255124 |
| CCNL1 | cyclin L1 | -0.0255075 |
| USP3 | ubiquitin specific peptidase 3 | -0.0254674 |
| RHBDD1 | rhomboid domain containing 1 | -0.0254417 |
| RPS23 | ribosomal protein S23 | -0.025303 |
| RIGI | RNA sensor RIG-I | -0.0252281 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0251662 |
