| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Torkinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Torkinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.120246 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.113312 |
| HDAC9 | histone deacetylase 9 | 0.104484 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0850097 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0774014 |
| SQSTM1 | sequestosome 1 | 0.0744732 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0719355 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.066766 |
| NAV2 | neuron navigator 2 | 0.064221 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0614484 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0604145 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0576156 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0551173 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0460113 |
| SFTPA2 | surfactant protein A2 | 0.0456101 |
| FNIP1 | folliculin interacting protein 1 | 0.0454176 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0448059 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0444303 |
| RND3 | Rho family GTPase 3 | 0.0430983 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0424792 |
| RPL23 | ribosomal protein L23 | 0.0423985 |
| MYOF | myoferlin | 0.0422702 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0422262 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0412833 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0411335 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0404514 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0401326 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0396566 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0395911 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0345102 |
| DUSP10 | dual specificity phosphatase 10 | 0.0341802 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0335065 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0332657 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0327432 |
| POTEF | POTE ankyrin domain family, member F | 0.0326723 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0325698 |
| FAM107B | family with sequence similarity 107, member B | 0.032469 |
| VIM | vimentin | 0.0324297 |
| CALR | calreticulin | 0.0322223 |
| ENO1 | enolase 1, (alpha) | 0.031622 |
| ADM | adrenomedullin | 0.031402 |
| RPS4X | ribosomal protein S4, X-linked | 0.0312829 |
| GOLGB1 | golgin B1 | 0.0306585 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0299801 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0296796 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0296511 |
| PCBP2 | poly(rC) binding protein 2 | 0.0292431 |
| ASPH | aspartate beta-hydroxylase | 0.0290529 |
| JMJD1C | jumonji domain containing 1C | 0.0286155 |
| INTS6 | integrator complex subunit 6 | 0.0286141 |
| MORF4L2 | mortality factor 4 like 2 | 0.0284071 |
| NOTCH2 | notch 2 | 0.0277783 |
| SYNJ2 | synaptojanin 2 | 0.0273325 |
| ANXA1 | annexin A1 | 0.027142 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0268849 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0264692 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0264234 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0259337 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0258783 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0253069 |
| FMNL2 | formin-like 2 | 0.0249864 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0247862 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0246883 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0243991 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0240836 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0237486 |
| RPS12 | ribosomal protein S12 | 0.0232721 |
| RPL3 | ribosomal protein L3 | 0.0230607 |
| GPHN | gephyrin | 0.0229051 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0228652 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0222164 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0221684 |
| RYBP | RING1 and YY1 binding protein | 0.0221521 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0220286 |
| RUNX1 | runt-related transcription factor 1 | 0.0220083 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.021835 |
| RPL27A | ribosomal protein L27a | 0.0212032 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0208497 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0208097 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0206831 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0206593 |
| ARRDC3 | arrestin domain containing 3 | 0.0206347 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0205073 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0204489 |
| RACK1 | receptor for activated C kinase 1 | 0.0202569 |
| SERINC5 | serine incorporator 5 | 0.0200654 |
| GPC6 | glypican 6 | 0.0200418 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0199659 |
| RPS18 | ribosomal protein S18 | 0.0199181 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0198774 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.019839 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0196045 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0193274 |
| CRY1 | cryptochrome circadian clock 1 | 0.019256 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0192428 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0191213 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0189813 |
| SVIL | supervillin | 0.0188329 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0188049 |
| RPLP0 | ribosomal protein, large, P0 | 0.0187676 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.20771 |
| FRMD4A | FERM domain containing 4A | -0.201091 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.1547 |
| GLIS3 | GLIS family zinc finger 3 | -0.113498 |
| BICC1 | BicC family RNA binding protein 1 | -0.105391 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0956646 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0814719 |
| VCL | vinculin | -0.0806695 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0803514 |
| RAI14 | retinoic acid induced 14 | -0.072898 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0710297 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0708082 |
| DST | dystonin | -0.0691608 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0674208 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.067022 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0650509 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0611228 |
| RTN4 | reticulon 4 | -0.0610892 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0597499 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0589405 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0558288 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0547435 |
| RNF213 | ring finger protein 213 | -0.0545189 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0504657 |
| NABP1 | nucleic acid binding protein 1 | -0.0502461 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0490803 |
| THBS1 | thrombospondin 1 | -0.0486524 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0486506 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0479204 |
| TPM4 | tropomyosin 4 | -0.0462475 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0446438 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0445728 |
| C3 | complement component 3 | -0.0435597 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0422175 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.041965 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0418419 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0412926 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0408313 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0407405 |
| HMGA2 | high mobility group AT-hook 2 | -0.0405811 |
| ZNF292 | zinc finger protein 292 | -0.0402272 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.039541 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391741 |
| MKI67 | marker of proliferation Ki-67 | -0.0389186 |
| RIGI | RNA sensor RIG-I | -0.0383886 |
| LRRC7 | leucine rich repeat containing 7 | -0.0380102 |
| THOC2 | THO complex 2 | -0.0374213 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0372644 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0370742 |
| COL1A1 | collagen, type I, alpha 1 | -0.0368713 |
| SBF2 | SET binding factor 2 | -0.0364646 |
| DIAPH2 | diaphanous-related formin 2 | -0.036233 |
| PALLD | palladin, cytoskeletal associated protein | -0.0354992 |
| RRBP1 | ribosome binding protein 1 | -0.0353469 |
| VCAN | versican | -0.0351615 |
| PGK1 | phosphoglycerate kinase 1 | -0.0348709 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.033856 |
| FTL | ferritin, light polypeptide | -0.0338384 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0332413 |
| EGFR | epidermal growth factor receptor | -0.0332212 |
| ANLN | anillin, actin binding protein | -0.0331018 |
| FRMD5 | FERM domain containing 5 | -0.0328721 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0323478 |
| OSMR | oncostatin M receptor | -0.0318042 |
| CALD1 | caldesmon 1 | -0.031549 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.031515 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0309679 |
| RUNX2 | runt-related transcription factor 2 | -0.0305364 |
| TMSB10 | thymosin beta 10 | -0.0304663 |
| CADM1 | cell adhesion molecule 1 | -0.0300299 |
| TENM2 | teneurin transmembrane protein 2 | -0.0297022 |
| CD2AP | CD2-associated protein | -0.0292358 |
| NCKAP5 | NCK-associated protein 5 | -0.0292109 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.029062 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0287855 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0287162 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0284178 |
| HDAC8 | histone deacetylase 8 | -0.0283373 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0276574 |
| MX1 | MX dynamin-like GTPase 1 | -0.0275357 |
| CDCP1 | CUB domain containing protein 1 | -0.0275284 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0273603 |
| PLPP6 | phospholipid phosphatase 6 | -0.0272424 |
| TXNRD1 | thioredoxin reductase 1 | -0.0271218 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0270751 |
| CLIC4 | chloride intracellular channel 4 | -0.0267729 |
| TNNC1 | troponin C type 1 (slow) | -0.026595 |
| TUBB | tubulin, beta class I | -0.0262113 |
| DIAPH3 | diaphanous-related formin 3 | -0.0261771 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0261317 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0260827 |
| COL1A2 | collagen, type I, alpha 2 | -0.0259828 |
| CLMP | CXADR-like membrane protein | -0.0259061 |
| AHNAK | AHNAK nucleoprotein | -0.0253796 |
| CENPF | centromere protein F, 350/400kDa | -0.0252413 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0251007 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0247335 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0245654 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0244287 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0242485 |
