Toxic Epidermal Necrolysis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0014518
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Genes

137 genes associated with the disease Toxic Epidermal Necrolysis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALB albumin
ALOX5 arachidonate 5-lipoxygenase
ANXA1 annexin A1
APC adenomatous polyposis coli
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
BAG6 BCL2-associated athanogene 6
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C5AR1 complement component 5a receptor 1
CABIN1 calcineurin binding protein 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL17 chemokine (C-C motif) ligand 17
CCL27 chemokine (C-C motif) ligand 27
CCR10 chemokine (C-C motif) receptor 10
CD274 CD274 molecule
CD33 CD33 molecule
CD37 CD37 molecule
CELF2 CUGBP, Elav-like family member 2
CFH complement factor H
COPS5 COP9 signalosome subunit 5
COX2
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
CUL4A cullin 4A
CXCL9 chemokine (C-X-C motif) ligand 9
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DERL1 derlin 1
DSP desmoplakin
EGFR epidermal growth factor receptor
ELMO1 engulfment and cell motility 1
EP300 E1A binding protein p300
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO6 F-box protein 6
FDXR ferredoxin reductase
FPR1 formyl peptide receptor 1
FSHB follicle stimulating hormone, beta polypeptide
GFER growth factor, augmenter of liver regeneration
GJA1 gap junction protein, alpha 1, 43kDa
GNLY granulysin
GSTM1 glutathione S-transferase mu 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HDLBP high density lipoprotein binding protein
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HSPG2 heparan sulfate proteoglycan 2
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL4 interleukin 4
IL4R interleukin 4 receptor
JAK2 Janus kinase 2
KEAP1 kelch-like ECH-associated protein 1
LMNA lamin A/C
MARCHF1 membrane associated ring-CH-type finger 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLKL mixed lineage kinase domain-like
MPRIP myosin phosphatase Rho interacting protein
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPY neuropeptide Y
NUCB1 nucleobindin 1
PAEP progestagen-associated endometrial protein
PANK2 pantothenate kinase 2
PARP1 poly (ADP-ribose) polymerase 1
PCM1 pericentriolar material 1
PLG plasminogen
PLXNA3 plexin A3
PML promyelocytic leukemia
POU5F1 POU class 5 homeobox 1
PROM1 prominin 1
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGIS prostaglandin I2 (prostacyclin) synthase
RB1 retinoblastoma 1
RBM45 RNA binding motif protein 45
RBX1 ring-box 1, E3 ubiquitin protein ligase
RET ret proto-oncogene
RIPK3 receptor-interacting serine-threonine kinase 3
SCN1A sodium channel, voltage gated, type I alpha subunit
SCO2 SCO2 cytochrome c oxidase assembly protein
SCT secretin
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SETX senataxin
SFRP1 secreted frizzled-related protein 1
SGSH N-sulfoglucosamine sulfohydrolase
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SOD1 superoxide dismutase 1, soluble
SPAG9 sperm associated antigen 9
SPTBN2 spectrin, beta, non-erythrocytic 2
TCF19 transcription factor 19
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
THBS1 thrombospondin 1
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TRAF3IP2 TRAF3 interacting protein 2
UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1
UPP1 uridine phosphorylase 1
VCP valosin containing protein
WASF1 WAS protein family, member 1
ZNF35 zinc finger protein 35