Toxoplasmosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A coccidiosis that has_material_basis_in protozoan Toxoplasma gondii. The parasite effects most genera of warm-blooded animals, including humans, but the primary host is the felid (cat) family. Animals are infected by eating infected meat, by ingestion of feces of a cat that has itself recently been infected, or transmission_by mother to fetus. The symptoms include bilateral, nontender cervical or axillary lymphadenopathy, fever, malaise, myalgia, hepatosplenomegaly, anemia and leukopenia. (Human Disease Ontology, DOID_9965)
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Genes

582 genes co-occuring with the disease Toxoplasmosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 3.119
IFNG interferon, gamma 3.088
CD8A CD8a molecule 2.787
IL10 interleukin 10 2.713
DHFR dihydrofolate reductase 2.642
BAG1 BCL2-associated athanogene 2.617
TNF tumor necrosis factor 2.605
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 2.482
IL6 interleukin 6 2.469
IL4 interleukin 4 2.465
IL2 interleukin 2 2.463
PFN4 profilin family, member 4 2.399
PFN3 profilin 3 2.394
IL1B interleukin 1, beta 2.393
DHFR2 dihydrofolate reductase 2 2.389
CRP C-reactive protein, pentraxin-related 2.363
IL17A interleukin 17A 2.333
MORN1 MORN repeat containing 1 2.323
ALB albumin 2.277
PFN1 profilin 1 2.235
MICOS13 mitochondrial contact site and cristae organizing system subunit 13 2.214
CD99 CD99 molecule 2.188
MYD88 myeloid differentiation primary response 88 2.181
TLR2 toll-like receptor 2 2.177
TLR4 toll-like receptor 4 2.135
STAT1 signal transducer and activator of transcription 1, 91kDa 2.09
NLRP1 NLR family, pyrin domain containing 1 2.084
ERVW-1 endogenous retrovirus group W, member 1 2.084
ACE angiotensin I converting enzyme 2.077
ERV3-1 endogenous retrovirus group 3, member 1 2.072
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.071
IL1A interleukin 1, alpha 2.063
TGFB1 transforming growth factor, beta 1 2.057
IL18 interleukin 18 2.054
PXDN peroxidasin 2.048
PXDNL peroxidasin-like 2.044
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.044
CD40 CD40 molecule, TNF receptor superfamily member 5 2.032
MYO1B myosin IB 2.031
PRF1 perforin 1 (pore forming protein) 2.025
TOX4 TOX high mobility group box family member 4 2.023
IDO1 indoleamine 2,3-dioxygenase 1 2.012
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 2.007
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.003
CCL2 chemokine (C-C motif) ligand 2 1.97
CXCL10 chemokine (C-X-C motif) ligand 10 1.967
IL5 interleukin 5 1.965
TLR9 toll-like receptor 9 1.959
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.945
TBX21 T-box 21 1.93
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.925
CENPV centromere protein V 1.925
CXCL8 chemokine (C-X-C motif) ligand 8 1.923
IFNA1 interferon, alpha 1 1.914
CD9 CD9 molecule 1.912
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.907
CD40LG CD40 ligand 1.902
IL13 interleukin 13 1.896
RHD Rh blood group, D antigen 1.889
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.88
IDO2 indoleamine 2,3-dioxygenase 2 1.875
TLR3 toll-like receptor 3 1.863
IFNB1 interferon, beta 1, fibroblast 1.86
MST1R macrophage stimulating 1 receptor 1.85
CD19 CD19 molecule 1.843
FOXP3 forkhead box P3 1.838
CETN1 centrin, EF-hand protein, 1 1.836
PTPRC protein tyrosine phosphatase, receptor type, C 1.833
ATF6B activating transcription factor 6 beta 1.823
HSPA4 heat shock 70kDa protein 4 1.814
CD86 CD86 molecule 1.812
IRGM immunity-related GTPase family, M 1.807
GBP1 guanylate binding protein 1, interferon-inducible 1.799
CD80 CD80 molecule 1.796
CD44 CD44 molecule (Indian blood group) 1.792
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.787
CCL3 chemokine (C-C motif) ligand 3 1.779
CCL5 chemokine (C-C motif) ligand 5 1.775
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.773
CD68 CD68 molecule 1.77
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.759
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.751
IL15 interleukin 15 1.745
CCR2 chemokine (C-C motif) receptor 2 1.745
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.745
AGRN agrin 1.743
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.738
HLA-B major histocompatibility complex, class I, B 1.731
CSF3 colony stimulating factor 3 (granulocyte) 1.723
MYH14 myosin, heavy chain 14, non-muscle 1.719
CCL4 chemokine (C-C motif) ligand 4 1.719
ICAM1 intercellular adhesion molecule 1 1.717
IFNGR1 interferon gamma receptor 1 1.706
IL27RA interleukin 27 receptor, alpha 1.698
CXCL9 chemokine (C-X-C motif) ligand 9 1.697
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.695
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.688
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.676
IL22 interleukin 22 1.67
ACTB actin, beta 1.667
H2BC21 H2B clustered histone 21 1.664
GBP2 guanylate binding protein 2, interferon-inducible 1.663
F2 coagulation factor II (thrombin) 1.661
TLR7 toll-like receptor 7 1.656
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.647
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.646
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.645
IRF8 interferon regulatory factor 8 1.642
CXCR3 chemokine (C-X-C motif) receptor 3 1.64
SELL selectin L 1.635
NOD2 nucleotide-binding oligomerization domain containing 2 1.631
CKM creatine kinase, muscle 1.631
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.626
CKB creatine kinase, brain 1.626
CKMT1B creatine kinase, mitochondrial 1B 1.625
HLA-A major histocompatibility complex, class I, A 1.618
PRTN3 proteinase 3 1.617
IL33 interleukin 33 1.612
ATAD1 ATPase family, AAA domain containing 1 1.604
CTSL cathepsin L 1.602
MAPK15 mitogen-activated protein kinase 15 1.6
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.589
USP18 ubiquitin specific peptidase 18 1.585
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.585
NOS2 nitric oxide synthase 2, inducible 1.581
B2M beta-2-microglobulin 1.573
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.568
LAMP1 lysosomal-associated membrane protein 1 1.566
IL7 interleukin 7 1.565
MOG myelin oligodendrocyte glycoprotein 1.562
F3 coagulation factor III (thromboplastin, tissue factor) 1.562
BCL2 B-cell CLL/lymphoma 2 1.561
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.56
ARG1 arginase 1 1.558
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.546
GJB2 gap junction protein, beta 2, 26kDa 1.542
NLRP3 NLR family, pyrin domain containing 3 1.541
SUB1 SUB1 homolog (S. cerevisiae) 1.534
ADA adenosine deaminase 1.531
IL1R1 interleukin 1 receptor, type I 1.524
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.52
IL12RB1 interleukin 12 receptor, beta 1 1.517
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.516
CD274 CD274 molecule 1.515
CD34 CD34 molecule 1.513
TLR5 toll-like receptor 5 1.511
HLA-G major histocompatibility complex, class I, G 1.51
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.506
RNASEH2B ribonuclease H2, subunit B 1.504
MAPK1 mitogen-activated protein kinase 1 1.498
SOCS1 suppressor of cytokine signaling 1 1.497
CCR7 chemokine (C-C motif) receptor 7 1.496
CETN2 centrin, EF-hand protein, 2 1.495
TP53 tumor protein p53 1.494
RNASEH2C ribonuclease H2, subunit C 1.494
IL7R interleukin 7 receptor 1.493
TUB tubby bipartite transcription factor 1.493
IRF3 interferon regulatory factor 3 1.491
MPO myeloperoxidase 1.489
CD28 CD28 molecule 1.488
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.488
ISG15 ISG15 ubiquitin-like modifier 1.484
UNC93B1 unc-93 homolog B1 (C. elegans) 1.483
CD69 CD69 molecule 1.477
JAK1 Janus kinase 1 1.477
INS insulin 1.475
PLK1 polo-like kinase 1 1.475
FDPS farnesyl diphosphate synthase 1.475
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.474
IRF1 interferon regulatory factor 1 1.47
NELFCD negative elongation factor complex member C/D 1.469
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.468
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.466
OTOF otoferlin 1.464
FASLG Fas ligand (TNF superfamily, member 6) 1.462
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.462
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.462
CXCR4 chemokine (C-X-C motif) receptor 4 1.459
NLRC4 NLR family, CARD domain containing 4 1.457
IFNA2 interferon, alpha 2 1.453
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.453
CD209 CD209 molecule 1.45
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.45
JUN jun proto-oncogene 1.446
GABARAPL2 GABA(A) receptor-associated protein-like 2 1.442
GBP5 guanylate binding protein 5 1.439
MBP myelin basic protein 1.438
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.435
ATG3 autophagy related 3 1.433
IL9 interleukin 9 1.429
GBP7 guanylate binding protein 7 1.428
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.427
CD1D CD1d molecule 1.423
L1CAM L1 cell adhesion molecule 1.423
NCAM1 neural cell adhesion molecule 1 1.422
MMP9 matrix metallopeptidase 9 1.42
SAMHD1 SAM domain and HD domain 1 1.419
RNASEH2A ribonuclease H2, subunit A 1.418
MORC1 MORC family CW-type zinc finger 1 1.418
AIM2 absent in melanoma 2 1.417
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.416
ENO1 enolase 1, (alpha) 1.414
TBL1X transducin (beta)-like 1X-linked 1.414
LSM11 LSM11, U7 small nuclear RNA associated 1.414
AIF1 allograft inflammatory factor 1 1.414
PRDM13 PR domain containing 13 1.406
STAT2 signal transducer and activator of transcription 2, 113kDa 1.406
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.406
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.405
GABARAPL1 GABA(A) receptor-associated protein like 1 1.403
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 1.402
MAPK3 mitogen-activated protein kinase 3 1.401
ENO2 enolase 2 (gamma, neuronal) 1.401
IL10RA interleukin 10 receptor, alpha 1.398
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.395
TYK2 tyrosine kinase 2 1.393
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.392
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.39
IRGC immunity-related GTPase family, cinema 1.389
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.389
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.389
CBS cystathionine-beta-synthase 1.387
AOC3 amine oxidase, copper containing 3 1.387
CD1C CD1c molecule 1.386
ATG5 autophagy related 5 1.386
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.385
AFP alpha-fetoprotein 1.382
TLR1 toll-like receptor 1 1.382
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.381
NLRP12 NLR family, pyrin domain containing 12 1.38
CD27 CD27 molecule 1.38
DNAH8 dynein, axonemal, heavy chain 8 1.379
IFNA17 interferon, alpha 17 1.377
SOCS3 suppressor of cytokine signaling 3 1.371
ATG7 autophagy related 7 1.37
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.364
CCL11 chemokine (C-C motif) ligand 11 1.364
CISH cytokine inducible SH2-containing protein 1.362
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.359
CD276 CD276 molecule 1.358
EOMES eomesodermin 1.358
PRKG1 protein kinase, cGMP-dependent, type I 1.357
CD163 CD163 molecule 1.357
IL12RB2 interleukin 12 receptor, beta 2 1.354
CXCL11 chemokine (C-X-C motif) ligand 11 1.352
MYO1C myosin IC 1.351
CD5 CD5 molecule 1.347
DHODH dihydroorotate dehydrogenase (quinone) 1.344
IFNA4 interferon, alpha 4 1.344
BECN1 beclin 1, autophagy related 1.344
ERAP1 endoplasmic reticulum aminopeptidase 1 1.342
CALML3 calmodulin-like 3 1.341
CP ceruloplasmin (ferroxidase) 1.341
HP haptoglobin 1.339
CYCS cytochrome c, somatic 1.338
IFNA8 interferon, alpha 8 1.336
IFNA6 interferon, alpha 6 1.335
PRDM1 PR domain containing 1, with ZNF domain 1.334
VCAM1 vascular cell adhesion molecule 1 1.333
TH tyrosine hydroxylase 1.331
IFNA14 interferon, alpha 14 1.33
CALML6 calmodulin-like 6 1.33
NTPCR nucleoside-triphosphatase, cancer-related 1.329
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 1.328
IFNA5 interferon, alpha 5 1.328
IFNA13 interferon, alpha 13 1.327
CALML5 calmodulin-like 5 1.327
IFNA16 interferon, alpha 16 1.324
IFNA10 interferon, alpha 10 1.323
IFNA7 interferon, alpha 7 1.323
CALML4 calmodulin-like 4 1.323
IFNA21 interferon, alpha 21 1.323
CD59 CD59 molecule, complement regulatory protein 1.323
IFIH1 interferon induced with helicase C domain 1 1.323
LTA lymphotoxin alpha 1.323
GYPC glycophorin C (Gerbich blood group) 1.322
BATF3 basic leucine zipper transcription factor, ATF-like 3 1.321
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.32
GBP3 guanylate binding protein 3 1.32
MAPK14 mitogen-activated protein kinase 14 1.319
RAG1 recombination activating gene 1 1.317
LGI1 leucine-rich, glioma inactivated 1 1.316
CD1B CD1b molecule 1.315
JAK2 Janus kinase 2 1.315
TLR8 toll-like receptor 8 1.313
C3 complement component 3 1.312
GFAP glial fibrillary acidic protein 1.311
HAVCR2 hepatitis A virus cellular receptor 2 1.31
IL3 interleukin 3 1.309
CSF1 colony stimulating factor 1 (macrophage) 1.308
HDAC9 histone deacetylase 9 1.307
RAG2 recombination activating gene 2 1.306
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 1.305
CD1A CD1a molecule 1.303
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.302
IL17RA interleukin 17 receptor A 1.299
EGF epidermal growth factor 1.297
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.297
IL21R interleukin 21 receptor 1.296
CD1E CD1e molecule 1.294
DHPS deoxyhypusine synthase 1.291
IL17F interleukin 17F 1.29
EGFR epidermal growth factor receptor 1.29
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.289
CYBB cytochrome b-245, beta polypeptide 1.289
BCL6 B-cell CLL/lymphoma 6 1.287
TXN thioredoxin 1.287
CAMLG calcium modulating ligand 1.286
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.285
CLEC7A C-type lectin domain family 7, member A 1.285
CXCL13 chemokine (C-X-C motif) ligand 13 1.285
TRIM21 tripartite motif containing 21 1.284
TLR6 toll-like receptor 6 1.284
HDAC3 histone deacetylase 3 1.283
MME membrane metallo-endopeptidase 1.281
GLB1 galactosidase, beta 1 1.281
CTSS cathepsin S 1.28
HLA-C major histocompatibility complex, class I, C 1.276
STX11 syntaxin 11 1.275
PRL prolactin 1.275
NLRP13 NLR family, pyrin domain containing 13 1.273
OCLN occludin 1.272
GJB6 gap junction protein, beta 6, 30kDa 1.269
NLRP6 NLR family, pyrin domain containing 6 1.269
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.269
CXCR5 chemokine (C-X-C motif) receptor 5 1.268
CGAS cyclic GMP-AMP synthase 1.267
ACE2 angiotensin I converting enzyme 2 1.265
ICOS inducible T-cell co-stimulator 1.262
UNC13D unc-13 homolog D (C. elegans) 1.26
TSPYL2 TSPY-like 2 1.26
ULK1 unc-51 like autophagy activating kinase 1 1.257
CD38 CD38 molecule 1.256
NOD1 nucleotide-binding oligomerization domain containing 1 1.255
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.253
MRC1 mannose receptor, C type 1 1.252
ACR acrosin 1.251
DERL1 derlin 1 1.251
NLRP8 NLR family, pyrin domain containing 8 1.25
IRF4 interferon regulatory factor 4 1.249
CD79A CD79a molecule, immunoglobulin-associated alpha 1.245
GGPS1 geranylgeranyl diphosphate synthase 1 1.245
NRL neural retina leucine zipper 1.243
BDNF brain-derived neurotrophic factor 1.243
POMC proopiomelanocortin 1.242
CCR1 chemokine (C-C motif) receptor 1 1.24
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.24
IRAK1 interleukin-1 receptor-associated kinase 1 1.24
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.239
H2AC20 H2A clustered histone 20 1.238
H2AC18 H2A clustered histone 18 1.237
AMPH amphiphysin 1.237
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.236
TOX thymocyte selection-associated high mobility group box 1.235
NCR1 natural cytotoxicity triggering receptor 1 1.235
ROM1 retinal outer segment membrane protein 1 1.234
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.234
ARG2 arginase 2 1.233
ADCY10 adenylate cyclase 10 (soluble) 1.231
FN1 fibronectin 1 1.229
NAIP NLR family, apoptosis inhibitory protein 1.229
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.227
UPP2 uridine phosphorylase 2 1.224
CD2 CD2 molecule 1.224
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.222
IRF7 interferon regulatory factor 7 1.222
CXCL12 chemokine (C-X-C motif) ligand 12 1.221
OR10H5 olfactory receptor, family 10, subfamily H, member 5 1.22
PLP1 proteolipid protein 1 1.22
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.217
PNMA2 paraneoplastic Ma antigen 2 1.216
RAB5A RAB5A, member RAS oncogene family 1.213
CTSC cathepsin C 1.211
LAG3 lymphocyte-activation gene 3 1.206
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.204
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.203
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.202
IRAK4 interleukin-1 receptor-associated kinase 4 1.202
RBP3 retinol binding protein 3, interstitial 1.2
ANXA5 annexin A5 1.199
DPYSL5 dihydropyrimidinase-like 5 1.196
SOCS2 suppressor of cytokine signaling 2 1.196
LCK LCK proto-oncogene, Src family tyrosine kinase 1.195
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.193
G6PD glucose-6-phosphate dehydrogenase 1.192
CXCR2 chemokine (C-X-C motif) receptor 2 1.191
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.189
SAG S-antigen; retina and pineal gland (arrestin) 1.185
AHR aryl hydrocarbon receptor 1.183
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.181
IL23R interleukin 23 receptor 1.181
NT5E 5'-nucleotidase, ecto (CD73) 1.18
CTSB cathepsin B 1.179
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.179
OXT oxytocin/neurophysin I prepropeptide 1.179
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.176
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 1.175
CST2 cystatin SA 1.174
ADK adenosine kinase 1.174
BIN1 bridging integrator 1 1.173
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 1.17
GSDMD gasdermin D 1.169
BST2 bone marrow stromal cell antigen 2 1.169
SCARB1 scavenger receptor class B, member 1 1.169
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 1.167
AARS1 alanyl-tRNA synthetase 1 1.166
DERA deoxyribose-phosphate aldolase (putative) 1.165
LTF lactotransferrin 1.162
CCK cholecystokinin 1.162
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 1.159
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.159
PTH parathyroid hormone 1.156
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.155
IL2RA interleukin 2 receptor, alpha 1.154
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.154
CORO7-PAM16 CORO7-PAM16 readthrough 1.154
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.153
IL27 interleukin 27 1.151
SORT1 sortilin 1 1.149
STXBP2 syntaxin binding protein 2 1.147
MX1 MX dynamin-like GTPase 1 1.144
RAB11A RAB11A, member RAS oncogene family 1.144
DRD1 dopamine receptor D1 1.143
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.142
BEST1 bestrophin 1 1.14
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.14
IRF9 interferon regulatory factor 9 1.14
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.139
LY75-CD302 LY75-CD302 readthrough 1.139
STAT5B signal transducer and activator of transcription 5B 1.137
RCVRN recoverin 1.136
TBK1 TANK-binding kinase 1 1.134
NGF nerve growth factor (beta polypeptide) 1.134
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.132
BTK Bruton agammaglobulinemia tyrosine kinase 1.132
SCARB2 scavenger receptor class B, member 2 1.132
TFRC transferrin receptor 1.131
FAS Fas cell surface death receptor 1.13
CNTNAP2 contactin associated protein-like 2 1.129
ATG12 autophagy related 12 1.128
CCL19 chemokine (C-C motif) ligand 19 1.126
GATA3 GATA binding protein 3 1.126
MXRA8 matrix-remodelling associated 8 1.124
KAT2A K(lysine) acetyltransferase 2A 1.124
HLA-DRA major histocompatibility complex, class II, DR alpha 1.123
TOR1B torsin family 1, member B (torsin B) 1.122
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.122
PLCE1 phospholipase C, epsilon 1 1.122
CIITA class II, major histocompatibility complex, transactivator 1.121
EPO erythropoietin 1.119
CCL22 chemokine (C-C motif) ligand 22 1.119
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.119
LY75 lymphocyte antigen 75 1.119
SDC1 syndecan 1 1.118
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.115
ADAR adenosine deaminase, RNA-specific 1.115
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.114
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.114
CCL20 chemokine (C-C motif) ligand 20 1.113
CD52 CD52 molecule 1.111
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.111
TYMS thymidylate synthetase 1.11
CD36 CD36 molecule (thrombospondin receptor) 1.11
CXCL2 chemokine (C-X-C motif) ligand 2 1.108
EIF4A2 eukaryotic translation initiation factor 4A2 1.108
PECAM1 platelet/endothelial cell adhesion molecule 1 1.107
CD200 CD200 molecule 1.105
SASS6 spindle assembly 6 homolog (C. elegans) 1.101
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.101
PYCARD PYD and CARD domain containing 1.1
PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.098
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.098
TDO2 tryptophan 2,3-dioxygenase 1.097
H4C7 H4 clustered histone 7 1.096
TIMP1 TIMP metallopeptidase inhibitor 1 1.095
PKM pyruvate kinase, muscle 1.095
EIF4A1 eukaryotic translation initiation factor 4A1 1.094
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.09
C4A complement component 4A (Rodgers blood group) 1.086
PAX5 paired box 5 1.084
MAVS mitochondrial antiviral signaling protein 1.083
PPARG peroxisome proliferator-activated receptor gamma 1.083
ELANE elastase, neutrophil expressed 1.08
MAPK8 mitogen-activated protein kinase 8 1.08
S100A11 S100 calcium binding protein A11 1.08
H4C6 H4 clustered histone 6 1.08
USP17L24 ubiquitin specific peptidase 17-like family member 24 1.079
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.078
FOXE3 forkhead box E3 1.076
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.075
YME1L1 YME1-like 1 ATPase 1.075
FOS FBJ murine osteosarcoma viral oncogene homolog 1.074
CCL7 chemokine (C-C motif) ligand 7 1.072
PNP purine nucleoside phosphorylase 1.072
MYORG myogenesis regulating glycosidase (putative) 1.071
MEFV Mediterranean fever 1.071
CD63 CD63 molecule 1.07
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.068
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.068
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.063
H3-3B H3.3 histone B 1.062
RIPK3 receptor-interacting serine-threonine kinase 3 1.06
ADCY9 adenylate cyclase 9 1.06
PDCD1LG2 programmed cell death 1 ligand 2 1.059
LRR1 leucine rich repeat protein 1 1.058
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.057
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.057
APOE apolipoprotein E 1.057
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.056
FDXR ferredoxin reductase 1.056
GBP6 guanylate binding protein family, member 6 1.056
KLK3 kallikrein-related peptidase 3 1.055
KAT2B K(lysine) acetyltransferase 2B 1.055
CXCL5 chemokine (C-X-C motif) ligand 5 1.052
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.052
IL23A interleukin 23, alpha subunit p19 1.052
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.051
TPI1 triosephosphate isomerase 1 1.051
H3C13 H3 clustered histone 13 1.05
H3-4 H3.4 histone, cluster member 1.049
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.049
IL1RN interleukin 1 receptor antagonist 1.049
UPP1 uridine phosphorylase 1 1.048
DRD5 dopamine receptor D5 1.047
TG thyroglobulin 1.046
STAT5A signal transducer and activator of transcription 5A 1.046
IGF1 insulin-like growth factor 1 (somatomedin C) 1.046
CIDEB cell death-inducing DFFA-like effector b 1.044
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta 1.044
COL4A1 collagen, type IV, alpha 1 1.042
H3-5 H3.5 histone 1.042
CENPA centromere protein A 1.04
CD33 CD33 molecule 1.039
HLA-E major histocompatibility complex, class I, E 1.039
IL26 interleukin 26 1.038
CARD9 caspase recruitment domain family, member 9 1.038
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.038
ATL1 atlastin GTPase 1 1.037
EPRS1 glutamyl-prolyl-tRNA synthetase 1 1.036
CALR calreticulin 1.036
PGK2 phosphoglycerate kinase 2 1.035
CARD8 caspase recruitment domain family, member 8 1.034
ESR1 estrogen receptor 1 1.034
APP amyloid beta (A4) precursor protein 1.034
SH2D1A SH2 domain containing 1A 1.033
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.031
CCL21 chemokine (C-C motif) ligand 21 1.031
NPIPB9 nuclear pore complex interacting protein family, member B9 1.03
PGAM2 phosphoglycerate mutase 2 (muscle) 1.03
H3C12 H3 clustered histone 12 1.03
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.03
HSPA1B heat shock 70kDa protein 1B 1.029
RSAD2 radical S-adenosyl methionine domain containing 2 1.028
PANX1 pannexin 1 1.027
MYOF myoferlin 1.027
MAOA monoamine oxidase A 1.025
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.024
IFITM1 interferon induced transmembrane protein 1 1.023
GMFB glia maturation factor, beta 1.022
IL33R interleukin 33 receptor 1.018
LGALSL lectin, galactoside-binding-like 1.017
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.017
SKA3 spindle and kinetochore associated complex subunit 3 1.016
MPPE1 metallophosphoesterase 1 1.016
BCL2L1 BCL2-like 1 1.016
IL4R interleukin 4 receptor 1.016
TUBE1 tubulin, epsilon 1 1.016
IFI16 interferon, gamma-inducible protein 16 1.015
IL17RC interleukin 17 receptor C 1.014
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.013
RAB30 RAB30, member RAS oncogene family 1.013
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.01
DRD2 dopamine receptor D2 1.009
LGALS3 lectin, galactoside-binding, soluble, 3 1.009
BATF basic leucine zipper transcription factor, ATF-like 1.007
IFITM3 interferon induced transmembrane protein 3 1.006
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.005
SPN sialophorin 1.001
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 1.001
SKP1 S-phase kinase-associated protein 1 1.001
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.0
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.0