Toxoplasmosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A coccidiosis that has_material_basis_in protozoan Toxoplasma gondii. The parasite effects most genera of warm-blooded animals, including humans, but the primary host is the felid (cat) family. Animals are infected by eating infected meat, by ingestion of feces of a cat that has itself recently been infected, or transmission_by mother to fetus. The symptoms include bilateral, nontender cervical or axillary lymphadenopathy, fever, malaise, myalgia, hepatosplenomegaly, anemia and leukopenia. (Human Disease Ontology, DOID_9965)
External Link https://www.disgenet.org/browser/0/1/0/C0040558
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Genes

106 genes associated with the disease Toxoplasmosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACO1 aconitase 1, soluble
ALOX12 arachidonate 12-lipoxygenase
BAX BCL2-associated X protein
BRCA1 breast cancer 1, early onset
C3 complement component 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCR1 chemokine (C-C motif) receptor 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CD99 CD99 molecule
CENPV centromere protein V
CHP1 calcineurin-like EF-hand protein 1
COX1
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTSB cathepsin B
CTSC cathepsin C
CXCL8 chemokine (C-X-C motif) ligand 8
DCTN3 dynactin 3 (p22)
DGAT1 diacylglycerol O-acyltransferase 1
DHFR dihydrofolate reductase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EBI3 Epstein-Barr virus induced 3
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
F2R coagulation factor II (thrombin) receptor
FDPS farnesyl diphosphate synthase
FUT2 fucosyltransferase 2 (secretor status included)
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBP5 guanylate binding protein 5
GDF15 growth differentiation factor 15
GGPS1 geranylgeranyl diphosphate synthase 1
GPAT3 glycerol-3-phosphate acyltransferase 3
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HM13 histocompatibility (minor) 13
HMGB1 high mobility group box 1
HSPA14 heat shock 70kDa protein 14
HSPA4 heat shock 70kDa protein 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPG2 heparan sulfate proteoglycan 2
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL10 interleukin 10
IL15 interleukin 15
IL17A interleukin 17A
IL17D interleukin 17D
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL27 interleukin 27
IL4 interleukin 4
IL6 interleukin 6
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IRF3 interferon regulatory factor 3
KEAP1 kelch-like ECH-associated protein 1
MAPK14 mitogen-activated protein kinase 14
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MYO1B myosin IB
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP3 NLR family, pyrin domain containing 3
NOX4 NADPH oxidase 4
OCA2 oculocutaneous albinism II
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PHB2 prohibitin 2
PLP1 proteolipid protein 1
PRDX1 peroxiredoxin 1
PSD pleckstrin and Sec7 domain containing
PTN pleiotrophin
RMC1 regulator of MON1-CCZ1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SKP1 S-phase kinase-associated protein 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
STING1 stimulator of interferon response cGAMP interactor 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TICAM2 toll-like receptor adaptor molecule 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TMPRSS11D transmembrane protease, serine 11D
TNF tumor necrosis factor
TPI1 triosephosphate isomerase 1
TRIM21 tripartite motif containing 21
TYMS thymidylate synthetase
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UNC93B1 unc-93 homolog B1 (C. elegans)