Trachoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea. (Human Disease Ontology, DOID_11265)
External Link https://www.disgenet.org/browser/0/1/0/C0040592
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Genes

36 genes associated with the disease Trachoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
CCL2 chemokine (C-C motif) ligand 2
CRP C-reactive protein, pentraxin-related
CXCL8 chemokine (C-X-C motif) ligand 8
EBI3 Epstein-Barr virus induced 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXP3 forkhead box P3
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL17A interleukin 17A
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLRC2 killer cell lectin-like receptor subfamily C, member 2
LMLN leishmanolysin-like (metallopeptidase M8 family)
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
OR10A4 olfactory receptor, family 10, subfamily A, member 4
RBM45 RNA binding motif protein 45
SEPTIN1 septin 1
TMPRSS13 transmembrane protease, serine 13
TNF tumor necrosis factor