| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/5526 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Tranexamic acid relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC158 | coiled-coil domain containing 158 | 1.36 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 1.36 |
| C7 | complement component 7 | 1.18 |
| MYO7B | myosin VIIB | 0.94 |
| RPS25 | ribosomal protein S25 | 0.64 |
| NOP10 | NOP10 ribonucleoprotein | 0.63 |
| CETN1 | centrin, EF-hand protein, 1 | 0.55 |
| YY1AP1 | YY1 associated protein 1 | 0.54 |
| RPS21 | ribosomal protein S21 | 0.52 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.51 |
| ZIC2 | Zic family member 2 | 0.5 |
| C8ORF76 | chromosome 8 open reading frame 76 | 0.49 |
| ZFHX3 | zinc finger homeobox 3 | 0.48 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 0.46 |
| MIER2 | mesoderm induction early response 1, family member 2 | 0.44 |
| MAGEA2 | melanoma antigen family A2 | 0.42 |
| ZNF431 | zinc finger protein 431 | 0.41 |
| GAS6 | growth arrest-specific 6 | 0.4 |
| LSM11 | LSM11, U7 small nuclear RNA associated | 0.4 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C | 0.39 |
| HIST1H1T | histone cluster 1, H1t | 0.39 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.39 |
| ENO1 | enolase 1, (alpha) | 0.37 |
| MAGEA12 | melanoma antigen family A12 | 0.36 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.36 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.35 |
| LDB1 | LIM domain binding 1 | 0.35 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.35 |
| MRPL35 | mitochondrial ribosomal protein L35 | 0.35 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.34 |
| TMC4 | transmembrane channel-like 4 | 0.34 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | 0.34 |
| LIN7A | lin-7 homolog A (C. elegans) | 0.33 |
| RWDD1 | RWD domain containing 1 | 0.32 |
| ZNF526 | zinc finger protein 526 | 0.32 |
| TPM2 | tropomyosin 2 (beta) | 0.31 |
| NCOR1 | nuclear receptor corepressor 1 | 0.31 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.31 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.31 |
| USP22 | ubiquitin specific peptidase 22 | 0.3 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.3 |
| ELK1 | ELK1, member of ETS oncogene family | 0.3 |
| GATD1 | glutamine amidotransferase class 1 domain containing 1 | 0.3 |
| ZNF462 | zinc finger protein 462 | 0.3 |
| NOP16 | NOP16 nucleolar protein | 0.3 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.3 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.3 |
| TRIM23 | tripartite motif containing 23 | 0.3 |
| SET | SET nuclear proto-oncogene | 0.3 |
| CAPRIN1 | cell cycle associated protein 1 | 0.3 |
| ACTBL2 | actin, beta-like 2 | 0.29 |
| SNX16 | sorting nexin 16 | 0.29 |
| FAM241B | family with sequence similarity 241 member B | 0.29 |
| TMPO | thymopoietin | 0.29 |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 0.29 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.29 |
| FN1 | fibronectin 1 | 0.28 |
| RTN2 | reticulon 2 | 0.28 |
| HIST2H2AA3 | histone cluster 2, H2aa3 | 0.28 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.28 |
| GPN1 | GPN-loop GTPase 1 | 0.28 |
| MSX2 | msh homeobox 2 | 0.28 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.28 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.28 |
| RPL37A | ribosomal protein L37a | 0.28 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.27 |
| ZNF567 | zinc finger protein 567 | 0.27 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.27 |
| ZNF428 | zinc finger protein 428 | 0.27 |
| CBX3 | chromobox homolog 3 | 0.27 |
| TRIM44 | tripartite motif containing 44 | 0.27 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.27 |
| SNX33 | sorting nexin 33 | 0.27 |
| HIST2H2BF | histone cluster 2, H2bf | 0.26 |
| PLK1 | polo-like kinase 1 | 0.26 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.26 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.26 |
| USB1 | U6 snRNA biogenesis 1 | 0.25 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.25 |
| TMEM222 | transmembrane protein 222 | 0.25 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.25 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.25 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.25 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.25 |
| PEX1 | peroxisomal biogenesis factor 1 | 0.25 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.25 |
| CDC34 | cell division cycle 34 | 0.25 |
| STRAP | serine/threonine kinase receptor associated protein | 0.25 |
| RPL27 | ribosomal protein L27 | 0.25 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.24 |
| APOBEC3D | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D | 0.24 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.24 |
| MANEA | mannosidase, endo-alpha | 0.24 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | 0.24 |
| CENPO | centromere protein O | 0.24 |
| CENPJ | centromere protein J | 0.24 |
| S100A4 | S100 calcium binding protein A4 | 0.24 |
| SELENOW | selenoprotein W | 0.24 |
| CENPP | centromere protein P | 0.23 |
| FAM192A | family with sequence similarity 192, member A | 0.23 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PIP | prolactin-induced protein | -0.94 |
| DAP | death-associated protein | -0.81 |
| GATA2 | GATA binding protein 2 | -0.68 |
| PLPP6 | phospholipid phosphatase 6 | -0.66 |
| MEGF6 | multiple EGF-like-domains 6 | -0.65 |
| RNF181 | ring finger protein 181 | -0.65 |
| LIPH | lipase, member H | -0.58 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | -0.58 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.54 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.53 |
| ZNF655 | zinc finger protein 655 | -0.53 |
| PHF1 | PHD finger protein 1 | -0.52 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.5 |
| DISP2 | dispatched homolog 2 (Drosophila) | -0.49 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | -0.49 |
| TBC1D16 | TBC1 domain family, member 16 | -0.48 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 | -0.48 |
| FZD2 | frizzled class receptor 2 | -0.48 |
| TREX1 | three prime repair exonuclease 1 | -0.48 |
| SH2B2 | SH2B adaptor protein 2 | -0.47 |
| CCDC167 | coiled-coil domain containing 167 | -0.47 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | -0.47 |
| MEX3C | mex-3 RNA binding family member C | -0.46 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | -0.45 |
| CLTCL1 | clathrin, heavy chain-like 1 | -0.45 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -0.45 |
| KIAA0825 | KIAA0825 | -0.44 |
| DNAH8 | dynein, axonemal, heavy chain 8 | -0.44 |
| GRAMD2A | GRAM domain containing 2A | -0.44 |
| KANK3 | KN motif and ankyrin repeat domains 3 | -0.44 |
| HMBOX1 | homeobox containing 1 | -0.44 |
| LINS1 | lines homolog 1 | -0.43 |
| VMA21 | VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) | -0.42 |
| NENF | neudesin neurotrophic factor | -0.42 |
| HGH1 | HGH1 homolog (S. cerevisiae) | -0.41 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.41 |
| FAT3 | FAT atypical cadherin 3 | -0.41 |
| MFSD6 | major facilitator superfamily domain containing 6 | -0.4 |
| ZSWIM7 | zinc finger, SWIM-type containing 7 | -0.4 |
| FGF19 | fibroblast growth factor 19 | -0.4 |
| NUCB2 | nucleobindin 2 | -0.4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.39 |
| CTSL | cathepsin L | -0.39 |
| EMC10 | ER membrane protein complex subunit 10 | -0.39 |
| TCAIM | T cell activation inhibitor, mitochondrial | -0.38 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -0.38 |
| ADCY6 | adenylate cyclase 6 | -0.38 |
| PTRHD1 | peptidyl-tRNA hydrolase domain containing 1 | -0.38 |
| RIBC2 | RIB43A domain with coiled-coils 2 | -0.38 |
| MPZL2 | myelin protein zero-like 2 | -0.38 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.37 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.37 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.37 |
| KRT8 | keratin 8, type II | -0.37 |
| ST5 | suppression of tumorigenicity 5 | -0.37 |
| N4BP3 | NEDD4 binding protein 3 | -0.36 |
| RNF135 | ring finger protein 135 | -0.36 |
| CBR1 | carbonyl reductase 1 | -0.36 |
| PTK6 | protein tyrosine kinase 6 | -0.35 |
| HPS4 | Hermansky-Pudlak syndrome 4 | -0.35 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.35 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.34 |
| FAM189B | family with sequence similarity 189, member B | -0.34 |
| FGGY | FGGY carbohydrate kinase domain containing | -0.34 |
| HAS3 | hyaluronan synthase 3 | -0.34 |
| ZBTB49 | zinc finger and BTB domain containing 49 | -0.34 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.33 |
| TMEM87B | transmembrane protein 87B | -0.33 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -0.33 |
| S100A11 | S100 calcium binding protein A11 | -0.33 |
| PHLDB3 | pleckstrin homology-like domain, family B, member 3 | -0.32 |
| GLRX | glutaredoxin (thioltransferase) | -0.32 |
| TSPAN3 | tetraspanin 3 | -0.31 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.31 |
| ARPIN | actin-related protein 2/3 complex inhibitor | -0.31 |
| CABLES2 | Cdk5 and Abl enzyme substrate 2 | -0.31 |
| SPPL3 | signal peptide peptidase like 3 | -0.3 |
| KPTN | kaptin (actin binding protein) | -0.3 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 | -0.3 |
| ABITRAM | actin binding transcription modulator | -0.3 |
| VGLL4 | vestigial-like family member 4 | -0.3 |
| PFDN1 | prefoldin subunit 1 | -0.3 |
| BOLA1 | bolA family member 1 | -0.3 |
| ANGPTL4 | angiopoietin-like 4 | -0.3 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.29 |
| ADPRH | ADP-ribosylarginine hydrolase | -0.29 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.29 |
| ZNF430 | zinc finger protein 430 | -0.29 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.29 |
| UBQLN1 | ubiquilin 1 | -0.29 |
| LRP11 | low density lipoprotein receptor-related protein 11 | -0.29 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.29 |
| TMEM231 | transmembrane protein 231 | -0.29 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.29 |
| ATE1 | arginyltransferase 1 | -0.28 |
| FKTN | fukutin | -0.28 |
| ANKRD12 | ankyrin repeat domain 12 | -0.28 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | -0.28 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.28 |
