| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tranilast_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0910447 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0782026 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0732843 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0706308 |
| MEIS2 | Meis homeobox 2 | 0.0599686 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.050374 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.048744 |
| TMSB10 | thymosin beta 10 | 0.046386 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.045173 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0428337 |
| LOX | lysyl oxidase | 0.0402934 |
| THBS2 | thrombospondin 2 | 0.0384277 |
| AHNAK | AHNAK nucleoprotein | 0.0337054 |
| MED13L | mediator complex subunit 13-like | 0.0311129 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0290462 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0281338 |
| TNS3 | tensin 3 | 0.0280811 |
| MSI2 | musashi RNA-binding protein 2 | 0.0278782 |
| FN1 | fibronectin 1 | 0.0270952 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0262055 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0255505 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0252203 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0251529 |
| TPM1 | tropomyosin 1 (alpha) | 0.0248968 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0242758 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0237958 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0234318 |
| JAZF1 | JAZF zinc finger 1 | 0.0223825 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0221124 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0217211 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0206447 |
| FBN1 | fibrillin 1 | 0.020407 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0201091 |
| EGR1 | early growth response 1 | 0.0199597 |
| PLXNA2 | plexin A2 | 0.0196463 |
| VEGFC | vascular endothelial growth factor C | 0.0195655 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.019486 |
| RASAL2 | RAS protein activator like 2 | 0.0191412 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0189565 |
| DCLK2 | doublecortin-like kinase 2 | 0.0188081 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0186671 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0183574 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.018339 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0179365 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0176676 |
| PRSS23 | protease, serine, 23 | 0.0174756 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0174541 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0174334 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0171902 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0167757 |
| SUCNR1 | succinate receptor 1 | 0.0166877 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0166778 |
| TUBB | tubulin, beta class I | 0.0162211 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0156639 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0155964 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0155637 |
| JUN | jun proto-oncogene | 0.0154886 |
| CDH13 | cadherin 13 | 0.0154446 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0154043 |
| CEP112 | centrosomal protein 112kDa | 0.0152709 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0152686 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0150605 |
| QKI | QKI, KH domain containing, RNA binding | 0.0147172 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0145802 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0145194 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0141647 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.014076 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0138093 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0134977 |
| FGF13 | fibroblast growth factor 13 | 0.0134092 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0132876 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0131671 |
| COPA | coatomer protein complex, subunit alpha | 0.0131635 |
| FTL | ferritin, light polypeptide | 0.0131371 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0130572 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0127731 |
| PRRX1 | paired related homeobox 1 | 0.0126373 |
| PDE10A | phosphodiesterase 10A | 0.0123413 |
| RIGI | RNA sensor RIG-I | 0.0122828 |
| IL7R | interleukin 7 receptor | 0.0121212 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.011979 |
| DMD | dystrophin | 0.0119014 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0117725 |
| GDI1 | GDP dissociation inhibitor 1 | 0.0117435 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0117118 |
| PRKD1 | protein kinase D1 | 0.011401 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0113478 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0113357 |
| GASK1B | golgi associated kinase 1B | 0.0112972 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0112836 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0112812 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0112316 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0109912 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0109415 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0108796 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0107921 |
| BSG | basigin (Ok blood group) | 0.010706 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0106682 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.0106583 |
| TFG | TRK-fused gene | 0.0106185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.217763 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.202744 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124852 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.120648 |
| PLAT | plasminogen activator, tissue | -0.0865926 |
| NDRG1 | N-myc downstream regulated 1 | -0.0826179 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0795697 |
| STC1 | stanniocalcin 1 | -0.078913 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0744364 |
| CD44 | CD44 molecule (Indian blood group) | -0.0734753 |
| MT2A | metallothionein 2A | -0.0704418 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0681254 |
| SQSTM1 | sequestosome 1 | -0.0660778 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0635839 |
| FLNB | filamin B, beta | -0.0607525 |
| SBF2 | SET binding factor 2 | -0.0606367 |
| MYADM | myeloid-associated differentiation marker | -0.0593101 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0568592 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0563696 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0551375 |
| SEPTIN9 | septin 9 | -0.0537864 |
| NAV2 | neuron navigator 2 | -0.0529883 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527671 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0525108 |
| OPTN | optineurin | -0.0523404 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.048599 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0474246 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0469093 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0467498 |
| ARFGEF3 | ARFGEF family member 3 | -0.0456291 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.045148 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0444706 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0425057 |
| CSTB | cystatin B (stefin B) | -0.04207 |
| CENPF | centromere protein F, 350/400kDa | -0.0419406 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0416287 |
| TMSB4X | thymosin beta 4, X-linked | -0.0410083 |
| LDHA | lactate dehydrogenase A | -0.0402487 |
| PRELID2 | PRELI domain containing 2 | -0.0398399 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0384024 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0382791 |
| LOXL2 | lysyl oxidase-like 2 | -0.038054 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0374483 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0372798 |
| APP | amyloid beta (A4) precursor protein | -0.0368818 |
| MYO9A | myosin IXA | -0.0366644 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0364524 |
| CANX | calnexin | -0.0363592 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0363376 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0362704 |
| FAM107B | family with sequence similarity 107, member B | -0.0361282 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0354326 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0353182 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.034924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0344213 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0340334 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0335402 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0333395 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0328596 |
| MYOF | myoferlin | -0.0327121 |
| SMYD3 | SET and MYND domain containing 3 | -0.0324099 |
| RPS2 | ribosomal protein S2 | -0.0322252 |
| SETD5 | SET domain containing 5 | -0.0319546 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0315469 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0315223 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0312589 |
| VEGFA | vascular endothelial growth factor A | -0.031257 |
| MYO9B | myosin IXB | -0.0307716 |
| MSN | moesin | -0.0305646 |
| STK10 | serine/threonine kinase 10 | -0.0305599 |
| B2M | beta-2-microglobulin | -0.0304002 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0302786 |
| TPM3 | tropomyosin 3 | -0.0302431 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.0301517 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0301169 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0300518 |
| TPM4 | tropomyosin 4 | -0.0295536 |
| SVIL | supervillin | -0.0294465 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0291601 |
| BPTF | bromodomain PHD finger transcription factor | -0.02906 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.028771 |
| NGLY1 | N-glycanase 1 | -0.0285209 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0279693 |
| PTMA | prothymosin, alpha | -0.0278465 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0277818 |
| RBM25 | RNA binding motif protein 25 | -0.0273944 |
| ZNF292 | zinc finger protein 292 | -0.0272941 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0271107 |
| S100A6 | S100 calcium binding protein A6 | -0.0268289 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | -0.0268172 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0267184 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0266492 |
| ANO6 | anoctamin 6 | -0.0265227 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0264273 |
| SP3 | Sp3 transcription factor | -0.0263574 |
| SEPTIN7 | septin 7 | -0.0263385 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0263288 |
| YEATS2 | YEATS domain containing 2 | -0.0259787 |
| COL3A1 | collagen, type III, alpha 1 | -0.0256528 |
| CTSB | cathepsin B | -0.0255948 |
