| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tranilast_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.114091 |
| COL6A3 | collagen, type VI, alpha 3 | 0.111519 |
| CDH13 | cadherin 13 | 0.111342 |
| COL1A1 | collagen, type I, alpha 1 | 0.0999934 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0776 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0761058 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0753631 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0702733 |
| COL5A1 | collagen, type V, alpha 1 | 0.0673129 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0523971 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.050329 |
| GLIS3 | GLIS family zinc finger 3 | 0.0491829 |
| FBN1 | fibrillin 1 | 0.048723 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0459096 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0392516 |
| CADM1 | cell adhesion molecule 1 | 0.0388406 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0378518 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0375195 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0360931 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0359771 |
| SMYD3 | SET and MYND domain containing 3 | 0.0350477 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0336543 |
| GOLGB1 | golgin B1 | 0.0336261 |
| NAV1 | neuron navigator 1 | 0.0327725 |
| CALD1 | caldesmon 1 | 0.0325604 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0312289 |
| DST | dystonin | 0.0305298 |
| VCL | vinculin | 0.029999 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0296192 |
| PDE10A | phosphodiesterase 10A | 0.0289821 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.02795 |
| PRELID2 | PRELI domain containing 2 | 0.0278228 |
| ATXN1 | ataxin 1 | 0.0275332 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0265215 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.026486 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0261534 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0261186 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0257007 |
| CMIP | c-Maf inducing protein | 0.0256426 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0255535 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0255418 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.025387 |
| FNIP1 | folliculin interacting protein 1 | 0.0252522 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0246679 |
| VMP1 | vacuole membrane protein 1 | 0.0244824 |
| HM13 | histocompatibility (minor) 13 | 0.0243058 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0238588 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0236272 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.023534 |
| HMGA2 | high mobility group AT-hook 2 | 0.0230649 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0229776 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0224751 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.022147 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0220986 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0218533 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0217278 |
| RUNX1 | runt-related transcription factor 1 | 0.021692 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0212243 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0210441 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0209681 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0208642 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0208463 |
| ZNF644 | zinc finger protein 644 | 0.0208244 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0206888 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0205632 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201074 |
| CUX1 | cut-like homeobox 1 | 0.0200225 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0199518 |
| NAV2 | neuron navigator 2 | 0.0199465 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0199158 |
| FAT1 | FAT atypical cadherin 1 | 0.0196694 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0194645 |
| CPQ | carboxypeptidase Q | 0.0193465 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0192474 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0189094 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0187804 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0187127 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0186181 |
| FRMD4A | FERM domain containing 4A | 0.0185924 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0182422 |
| CDK13 | cyclin-dependent kinase 13 | 0.0179357 |
| ASPH | aspartate beta-hydroxylase | 0.0179256 |
| ANKRD17 | ankyrin repeat domain 17 | 0.017741 |
| DGKI | diacylglycerol kinase, iota | 0.0176234 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0173667 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.017253 |
| PGM3 | phosphoglucomutase 3 | 0.0172432 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0171508 |
| PLEC | plectin | 0.0171175 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0171163 |
| EGFR | epidermal growth factor receptor | 0.0171157 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0170547 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.016774 |
| FMNL2 | formin-like 2 | 0.0167714 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0166948 |
| EBF1 | early B-cell factor 1 | 0.0166843 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0165978 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0165959 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0165114 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0164653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.246877 |
| MT2A | metallothionein 2A | -0.23691 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.206618 |
| VIM | vimentin | -0.206487 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.164096 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.141047 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.130746 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0962227 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0942143 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0923995 |
| NDRG1 | N-myc downstream regulated 1 | -0.0872381 |
| MT1X | metallothionein 1X | -0.0745156 |
| CD44 | CD44 molecule (Indian blood group) | -0.0736667 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0704337 |
| LDHA | lactate dehydrogenase A | -0.070041 |
| B2M | beta-2-microglobulin | -0.0690395 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0647312 |
| TMSB10 | thymosin beta 10 | -0.0587604 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0572085 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0525764 |
| PTMA | prothymosin, alpha | -0.052452 |
| STC1 | stanniocalcin 1 | -0.0521589 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0498889 |
| YBX1 | Y box binding protein 1 | -0.0485873 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0479937 |
| PFN1 | profilin 1 | -0.0451758 |
| RPS6 | ribosomal protein S6 | -0.0446474 |
| CALR | calreticulin | -0.0433583 |
| PKM | pyruvate kinase, muscle | -0.0425036 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0405909 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0405322 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0403511 |
| HMGA1 | high mobility group AT-hook 1 | -0.0401804 |
| ARRDC3 | arrestin domain containing 3 | -0.0400948 |
| SEPTIN7 | septin 7 | -0.037956 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0371485 |
| ANXA2 | annexin A2 | -0.0370985 |
| RPL8 | ribosomal protein L8 | -0.0368358 |
| ZNF292 | zinc finger protein 292 | -0.0362875 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0350511 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0346852 |
| RPLP0 | ribosomal protein, large, P0 | -0.0338453 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0338332 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0337734 |
| USP3 | ubiquitin specific peptidase 3 | -0.0337377 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0337253 |
| RPL19 | ribosomal protein L19 | -0.0332882 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0325795 |
| DSTN | destrin (actin depolymerizing factor) | -0.0324699 |
| AXL | AXL receptor tyrosine kinase | -0.0324509 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0323975 |
| TMSB4X | thymosin beta 4, X-linked | -0.0322938 |
| S100A10 | S100 calcium binding protein A10 | -0.0321471 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0320767 |
| MAP1B | microtubule-associated protein 1B | -0.0320041 |
| RPS8 | ribosomal protein S8 | -0.0313341 |
| RPL18 | ribosomal protein L18 | -0.0311359 |
| WASF2 | WAS protein family, member 2 | -0.0303667 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0303045 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0302404 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0301888 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0299843 |
| TAGLN2 | transgelin 2 | -0.0298841 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0296759 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.029605 |
| RPL12 | ribosomal protein L12 | -0.0294909 |
| FOSL1 | FOS-like antigen 1 | -0.029335 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0293007 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0292692 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0290544 |
| RPS19 | ribosomal protein S19 | -0.0284241 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0282041 |
| KLF6 | Kruppel-like factor 6 | -0.0281332 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0278953 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0275884 |
| TPI1 | triosephosphate isomerase 1 | -0.0273052 |
| SPAG9 | sperm associated antigen 9 | -0.0270512 |
| RASA2 | RAS p21 protein activator 2 | -0.0270004 |
| SRGN | serglycin | -0.0269719 |
| GNAS | GNAS complex locus | -0.0267831 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0262626 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0259331 |
| SQLE | squalene epoxidase | -0.0258923 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0257046 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0250252 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0246212 |
| TRAM1 | translocation associated membrane protein 1 | -0.0245972 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0244776 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.024278 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0241653 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0241642 |
| COL1A2 | collagen, type I, alpha 2 | -0.0238952 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | -0.0235122 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0234186 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0231655 |
| ECE1 | endothelin converting enzyme 1 | -0.0231287 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0231023 |
| PTN | pleiotrophin | -0.0228071 |
| ATL1 | atlastin GTPase 1 | -0.0226378 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0225594 |
