| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tranilast_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.270923 |
| APOB | apolipoprotein B | 0.135309 |
| FN1 | fibronectin 1 | 0.0772579 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0408209 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0393045 |
| SVIL | supervillin | 0.0357282 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0346 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0324002 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0309659 |
| DSPP | dentin sialophosphoprotein | 0.028701 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0269453 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0261563 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0260534 |
| ITGAV | integrin, alpha V | 0.0257482 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0253314 |
| A2M | alpha-2-macroglobulin | 0.0234019 |
| H1-0 | H1.0 linker histone | 0.0227677 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0224814 |
| FAT1 | FAT atypical cadherin 1 | 0.0222702 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0219287 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0216296 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0211899 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0205163 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0200421 |
| MATR3 | matrin 3 | 0.0200149 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0195457 |
| RPL3 | ribosomal protein L3 | 0.0194701 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0191956 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0191307 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0191106 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0189731 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0189047 |
| C3 | complement component 3 | 0.0187707 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0185124 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0184422 |
| CORO1C | coronin, actin binding protein, 1C | 0.0183268 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0180833 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.017773 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0176128 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0175269 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.017392 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0173449 |
| VCL | vinculin | 0.0173072 |
| NBAS | neuroblastoma amplified sequence | 0.0172046 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0171804 |
| SKIL | SKI-like proto-oncogene | 0.0168502 |
| XPO1 | exportin 1 | 0.0168073 |
| BCL2L1 | BCL2-like 1 | 0.0167191 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0167142 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0164106 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0163481 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0160829 |
| MTSS1 | metastasis suppressor 1 | 0.0160711 |
| OGA | O-GlcNAcase | 0.0155347 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0154246 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0153856 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0152612 |
| DENND5A | DENN/MADD domain containing 5A | 0.0152378 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0152107 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.015075 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0150414 |
| NRDC | nardilysin convertase | 0.0149703 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0149374 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0148754 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0147369 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0146985 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0145695 |
| FERMT2 | fermitin family member 2 | 0.0145577 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0144294 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0143667 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0143596 |
| IPO7 | importin 7 | 0.0143567 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0143304 |
| ETNK1 | ethanolamine kinase 1 | 0.0143185 |
| KYNU | kynureninase | 0.0142231 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0140484 |
| GLG1 | golgi glycoprotein 1 | 0.0139154 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.013904 |
| DIAPH1 | diaphanous-related formin 1 | 0.0138771 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0138523 |
| USP34 | ubiquitin specific peptidase 34 | 0.0137787 |
| ANXA5 | annexin A5 | 0.0137508 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.01359 |
| EEA1 | early endosome antigen 1 | 0.0135812 |
| WWOX | WW domain containing oxidoreductase | 0.0134908 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0133718 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0133446 |
| CFB | complement factor B | 0.0133335 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.013328 |
| CLTB | clathrin, light chain B | 0.0132764 |
| KIF1B | kinesin family member 1B | 0.0132358 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0131891 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0131443 |
| PLAC8 | placenta-specific 8 | 0.0130799 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0129694 |
| SERINC1 | serine incorporator 1 | 0.012845 |
| RUNX1 | runt-related transcription factor 1 | 0.0128302 |
| PDZD8 | PDZ domain containing 8 | 0.0128269 |
| ADAR | adenosine deaminase, RNA-specific | 0.0123802 |
| MRTFA | myocardin related transcription factor A | 0.0122517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.433782 |
| MT2A | metallothionein 2A | -0.117218 |
| RPL37A | ribosomal protein L37a | -0.101362 |
| RPS12 | ribosomal protein S12 | -0.0904731 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0881425 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0853376 |
| APOA2 | apolipoprotein A-II | -0.0814428 |
| RPS6 | ribosomal protein S6 | -0.0761911 |
| RPL23 | ribosomal protein L23 | -0.0636521 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0623845 |
| EHBP1 | EH domain binding protein 1 | -0.0620887 |
| RPL26 | ribosomal protein L26 | -0.0603237 |
| RPL31 | ribosomal protein L31 | -0.0591823 |
| RPS3 | ribosomal protein S3 | -0.0548678 |
| GPC6 | glypican 6 | -0.0544915 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0543637 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0514463 |
| TMSB10 | thymosin beta 10 | -0.0506926 |
| RPS19 | ribosomal protein S19 | -0.048696 |
| RPS29 | ribosomal protein S29 | -0.04868 |
| RPL11 | ribosomal protein L11 | -0.0485318 |
| RPLP2 | ribosomal protein, large, P2 | -0.0482377 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0473948 |
| AHSG | alpha-2-HS-glycoprotein | -0.0473387 |
| RPL9 | ribosomal protein L9 | -0.0473175 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0468024 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0465758 |
| RPS8 | ribosomal protein S8 | -0.0448405 |
| RPS13 | ribosomal protein S13 | -0.0443623 |
| RNASET2 | ribonuclease T2 | -0.0437461 |
| RPS23 | ribosomal protein S23 | -0.0405313 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0399239 |
| RPL36 | ribosomal protein L36 | -0.0396047 |
| CP | ceruloplasmin (ferroxidase) | -0.0388197 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0385809 |
| RPS17 | ribosomal protein S17 | -0.0361801 |
| RPS27A | ribosomal protein S27a | -0.0350568 |
| RPL32 | ribosomal protein L32 | -0.0346507 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0340415 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0337663 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0336068 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0334351 |
| HMGA1 | high mobility group AT-hook 1 | -0.0333023 |
| TMEM123 | transmembrane protein 123 | -0.0326792 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0315039 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0308274 |
| RPL12 | ribosomal protein L12 | -0.0307102 |
| PTMA | prothymosin, alpha | -0.0306321 |
| FTL | ferritin, light polypeptide | -0.0304071 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0302375 |
| RPS24 | ribosomal protein S24 | -0.0300081 |
| ZFHX3 | zinc finger homeobox 3 | -0.0299982 |
| RPL38 | ribosomal protein L38 | -0.0294866 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0287708 |
| RPL13A | ribosomal protein L13a | -0.0283796 |
| RPL18 | ribosomal protein L18 | -0.0281891 |
| RPL27 | ribosomal protein L27 | -0.027569 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0274523 |
| RPS21 | ribosomal protein S21 | -0.0274484 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027435 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0271202 |
| RPL36A | ribosomal protein L36a | -0.026418 |
| PERP | PERP, TP53 apoptosis effector | -0.0262016 |
| RPS25 | ribosomal protein S25 | -0.026186 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0260191 |
| ENO1 | enolase 1, (alpha) | -0.0255508 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0251285 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0250942 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0250838 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.024769 |
| RPL7A | ribosomal protein L7a | -0.0246417 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0246105 |
| RPS10 | ribosomal protein S10 | -0.0244057 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0243514 |
| RPL35A | ribosomal protein L35a | -0.0241841 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0241662 |
| RPS11 | ribosomal protein S11 | -0.0240656 |
| GK | glycerol kinase | -0.0238446 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0238381 |
| HMGA2 | high mobility group AT-hook 2 | -0.0232746 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.0229101 |
| FAM135A | family with sequence similarity 135, member A | -0.0228163 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.022647 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0224814 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0224036 |
| PEG3 | paternally expressed 3 | -0.0222146 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0221273 |
| TPM4 | tropomyosin 4 | -0.0220987 |
| TF | transferrin | -0.0218146 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0216065 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0215862 |
| RPL28 | ribosomal protein L28 | -0.0213869 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0212147 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0211306 |
| LDHA | lactate dehydrogenase A | -0.0211064 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0210723 |
| RPL8 | ribosomal protein L8 | -0.0210595 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0209075 |
| HLA-A | major histocompatibility complex, class I, A | -0.0208969 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0208573 |
