| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tranilast_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0405945 |
| VCL | vinculin | 0.0283355 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0133321 |
| GOLGB1 | golgin B1 | 0.0130905 |
| MYO1E | myosin IE | 0.0129656 |
| RPL3 | ribosomal protein L3 | 0.0129141 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0115644 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0112362 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0111983 |
| LAMA4 | laminin, alpha 4 | 0.0106423 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00936257 |
| MUC13 | mucin 13, cell surface associated | 0.00897801 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0087677 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00839104 |
| VEGFA | vascular endothelial growth factor A | 0.00827565 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00801587 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.00768592 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00765984 |
| INTS6 | integrator complex subunit 6 | 0.0074949 |
| MCL1 | myeloid cell leukemia 1 | 0.00744581 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.00739214 |
| NABP1 | nucleic acid binding protein 1 | 0.00711076 |
| MUC3B | mucin 3B, cell surface associated | 0.00697815 |
| EGR1 | early growth response 1 | 0.00696511 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.00685444 |
| AREG | amphiregulin | 0.00668527 |
| LRATD1 | LRAT domain containing 1 | 0.00664224 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00657632 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00650468 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.00642105 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0062774 |
| PFKL | phosphofructokinase, liver | 0.00613283 |
| PALLD | palladin, cytoskeletal associated protein | 0.00603654 |
| POTEF | POTE ankyrin domain family, member F | 0.00589172 |
| PRR5L | proline rich 5 like | 0.00575853 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.00570597 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00567858 |
| CFAP44 | cilia and flagella associated protein 44 | 0.00562774 |
| TMF1 | TATA element modulatory factor 1 | 0.00555993 |
| PCNX4 | pecanex 4 | 0.00551488 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00550241 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00546462 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.00542712 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00535636 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00529422 |
| ZFP36 | ZFP36 ring finger protein | 0.00524579 |
| SETX | senataxin | 0.00513693 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00511531 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00508197 |
| LYST | lysosomal trafficking regulator | 0.00496843 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.00496117 |
| FBXW10B | F-box and WD repeat domain containing 10B | 0.00495718 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.004938 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.00491731 |
| DSTN | destrin (actin depolymerizing factor) | 0.00491444 |
| RIGI | RNA sensor RIG-I | 0.00487074 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00483077 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.00481562 |
| ANXA3 | annexin A3 | 0.00472828 |
| HDGF | hepatoma-derived growth factor | 0.00465775 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.00463419 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.00458611 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.00455156 |
| IFI44 | interferon-induced protein 44 | 0.00454753 |
| ZNF75D | zinc finger protein 75D | 0.00451137 |
| SETD1B | SET domain containing 1B | 0.00450459 |
| RPL21 | ribosomal protein L21 | 0.00449394 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.00449351 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.00448313 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00446347 |
| BAG6 | BCL2-associated athanogene 6 | 0.00442794 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00442008 |
| HNF4G | hepatocyte nuclear factor 4, gamma | 0.00438127 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.00436805 |
| MSN | moesin | 0.00434645 |
| UBAP2 | ubiquitin associated protein 2 | 0.00434345 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.00434075 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00434029 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00431053 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00430524 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.00427912 |
| MBD6 | methyl-CpG binding domain protein 6 | 0.00427615 |
| KIAA2026 | KIAA2026 | 0.00426075 |
| CHMP4C | charged multivesicular body protein 4C | 0.00424026 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.00420256 |
| CFAP161 | cilia and flagella associated protein 161 | 0.00420255 |
| SNX3 | sorting nexin 3 | 0.00420125 |
| GTPBP1 | GTP binding protein 1 | 0.00419028 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 0.00418834 |
| CYTH2 | cytohesin 2 | 0.00416273 |
| RAB8A | RAB8A, member RAS oncogene family | 0.00413719 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00413401 |
| GLRX | glutaredoxin (thioltransferase) | 0.00411698 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.00408998 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.00408082 |
| TLNRD1 | talin rod domain containing 1 | 0.00407974 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00407695 |
| TOB1 | transducer of ERBB2, 1 | 0.00407082 |
| ZNF432 | zinc finger protein 432 | 0.00405514 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.00405149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134277 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0864104 |
| TMSB10 | thymosin beta 10 | -0.0850165 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0836942 |
| PTMA | prothymosin, alpha | -0.0654583 |
| PGK1 | phosphoglycerate kinase 1 | -0.0571409 |
| ANXA2 | annexin A2 | -0.0544826 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0483011 |
| ITGA6 | integrin, alpha 6 | -0.0478327 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0452307 |
| MED13L | mediator complex subunit 13-like | -0.0441296 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0425453 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0412848 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0405948 |
| EREG | epiregulin | -0.0404522 |
| AHNAK | AHNAK nucleoprotein | -0.0397435 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.039716 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0394466 |
| EZR | ezrin | -0.0389733 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0387762 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0375943 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0358717 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0358682 |
| RPS6 | ribosomal protein S6 | -0.0357746 |
| FNBP1L | formin binding protein 1-like | -0.0356505 |
| GPHN | gephyrin | -0.0356285 |
| RPLP1 | ribosomal protein, large, P1 | -0.03557 |
| FAM13A | family with sequence similarity 13, member A | -0.0355394 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0351512 |
| RPL35A | ribosomal protein L35a | -0.0347157 |
| LDHA | lactate dehydrogenase A | -0.0345647 |
| ZNF292 | zinc finger protein 292 | -0.0345556 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0340341 |
| KRT18 | keratin 18, type I | -0.0338927 |
| RPS24 | ribosomal protein S24 | -0.0337912 |
| RBM39 | RNA binding motif protein 39 | -0.0336016 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0335973 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0332932 |
| LOC112694756 | uncharaterized LOC112694756 | -0.032544 |
| FLNB | filamin B, beta | -0.0324155 |
| NDRG1 | N-myc downstream regulated 1 | -0.0318487 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0317398 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0312814 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0310572 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0310068 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0302085 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0300345 |
| PIGR | polymeric immunoglobulin receptor | -0.0298077 |
| LMO7 | LIM domain 7 | -0.0296723 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0294672 |
| NPSR1 | neuropeptide S receptor 1 | -0.0293372 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0292152 |
| PARD3 | par-3 family cell polarity regulator | -0.0282236 |
| CD2AP | CD2-associated protein | -0.0279293 |
| CANX | calnexin | -0.0278916 |
| RNF145 | ring finger protein 145 | -0.0272905 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0270388 |
| MED13 | mediator complex subunit 13 | -0.0268894 |
| SERINC5 | serine incorporator 5 | -0.0267569 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267381 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0266253 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0263177 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0262688 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0260598 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0260101 |
| FTL | ferritin, light polypeptide | -0.0258433 |
| OGA | O-GlcNAcase | -0.0258352 |
| HDLBP | high density lipoprotein binding protein | -0.0252514 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0251332 |
| TFG | TRK-fused gene | -0.0251199 |
| NF1 | neurofibromin 1 | -0.0251021 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0250827 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.024973 |
| RREB1 | ras responsive element binding protein 1 | -0.0248007 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0247991 |
| USP3 | ubiquitin specific peptidase 3 | -0.024714 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0246594 |
| ACTG1 | actin gamma 1 | -0.0245729 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0244261 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0240439 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0238609 |
| PUM2 | pumilio RNA-binding family member 2 | -0.02382 |
| ONECUT3 | one cut homeobox 3 | -0.0238179 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0237275 |
| ACTN4 | actinin, alpha 4 | -0.0236131 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0234145 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0233812 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0233584 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0233172 |
| RPL34 | ribosomal protein L34 | -0.0232611 |
| JMJD1C | jumonji domain containing 1C | -0.0230731 |
| CCNY | cyclin Y | -0.0230042 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0228133 |
| S100A6 | S100 calcium binding protein A6 | -0.022418 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0223706 |
| RLF | rearranged L-myc fusion | -0.022269 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0221838 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0221187 |
| RPLP0 | ribosomal protein, large, P0 | -0.0218632 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0218108 |
