| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tranilast_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.107481 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.068681 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0606352 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0604822 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0570093 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0535455 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0478036 |
| CD109 | CD109 molecule | 0.0431239 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0414331 |
| SMYD3 | SET and MYND domain containing 3 | 0.0408081 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0390938 |
| PTMA | prothymosin, alpha | 0.0384563 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0382903 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.037486 |
| CADM1 | cell adhesion molecule 1 | 0.0366018 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0364459 |
| ABI1 | abl-interactor 1 | 0.035501 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.035491 |
| HELZ | helicase with zinc finger | 0.0354173 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0346506 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0344821 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0338485 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0337486 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0332137 |
| NBAS | neuroblastoma amplified sequence | 0.0330706 |
| RORA | RAR-related orphan receptor A | 0.0330603 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0319532 |
| TAGLN2 | transgelin 2 | 0.0316031 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.031598 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.031188 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0311015 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0310497 |
| GLG1 | golgi glycoprotein 1 | 0.0309813 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0308365 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0308243 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0303878 |
| RBM25 | RNA binding motif protein 25 | 0.0303522 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0303314 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0301959 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0299543 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0299393 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0296262 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0293691 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0293678 |
| PGK1 | phosphoglycerate kinase 1 | 0.0292101 |
| CENPF | centromere protein F, 350/400kDa | 0.0289103 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0281591 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0280922 |
| TPD52 | tumor protein D52 | 0.028032 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0279121 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0278369 |
| OTUD4 | OTU deubiquitinase 4 | 0.0276634 |
| DTNA | dystrobrevin, alpha | 0.0275067 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0272359 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0270825 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0267875 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0267872 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0265604 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0264727 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0264578 |
| PRELID2 | PRELI domain containing 2 | 0.0263341 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0258799 |
| VIM | vimentin | 0.0258068 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.025786 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0257433 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0255197 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0254253 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0253865 |
| RBM39 | RNA binding motif protein 39 | 0.0251528 |
| NUP58 | nucleoporin 58 | 0.0251499 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0250083 |
| ZNF407 | zinc finger protein 407 | 0.0249847 |
| NEMF | nuclear export mediator factor | 0.0249557 |
| NCKAP5 | NCK-associated protein 5 | 0.0248304 |
| NRG1 | neuregulin 1 | 0.024726 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0246957 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0245801 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0244125 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0244051 |
| CABIN1 | calcineurin binding protein 1 | 0.02438 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0242083 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0240248 |
| PDS5B | PDS5 cohesin associated factor B | 0.023987 |
| CDC73 | cell division cycle 73 | 0.0239389 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0238755 |
| SERINC3 | serine incorporator 3 | 0.0234659 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0234418 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0233178 |
| NAV2 | neuron navigator 2 | 0.0233153 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0232589 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0232076 |
| GPC6 | glypican 6 | 0.0231539 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0231091 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0230571 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0229018 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0227428 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0226878 |
| CANX | calnexin | 0.0225949 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0225786 |
| ATP13A3 | ATPase type 13A3 | 0.0224861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101093 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0988107 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0975652 |
| KRT17 | keratin 17, type I | -0.0902015 |
| NDRG1 | N-myc downstream regulated 1 | -0.0857309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0849745 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.082096 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0739408 |
| LAMC2 | laminin, gamma 2 | -0.0738461 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.073716 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0733905 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.070575 |
| ASPH | aspartate beta-hydroxylase | -0.0675319 |
| LAMB3 | laminin, beta 3 | -0.0585304 |
| STC1 | stanniocalcin 1 | -0.056122 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0560462 |
| POTEF | POTE ankyrin domain family, member F | -0.0527552 |
| FTL | ferritin, light polypeptide | -0.0523682 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0515001 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0509734 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0507045 |
| ANXA2 | annexin A2 | -0.0497108 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0496279 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0482045 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0466078 |
| LMO7 | LIM domain 7 | -0.0459178 |
| ATOSA | atos homolog A | -0.0437615 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.042969 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.042255 |
| MUC16 | mucin 16, cell surface associated | -0.0415449 |
| TPM4 | tropomyosin 4 | -0.0410618 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0408308 |
| SVIL | supervillin | -0.040102 |
| PARD3 | par-3 family cell polarity regulator | -0.0400322 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0393569 |
| MYO1E | myosin IE | -0.039318 |
| S100A6 | S100 calcium binding protein A6 | -0.0389737 |
| RPLP0 | ribosomal protein, large, P0 | -0.0388952 |
| EZR | ezrin | -0.0386044 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0377266 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0372856 |
| RPS16 | ribosomal protein S16 | -0.0371111 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0366039 |
| ACTG1 | actin gamma 1 | -0.0361848 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0358192 |
| PRKCA | protein kinase C, alpha | -0.0348327 |
| OSMR | oncostatin M receptor | -0.0343909 |
| ABHD17C | abhydrolase domain containing 17C | -0.0338806 |
| ANXA1 | annexin A1 | -0.0338621 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0336595 |
| ERBIN | erbb2 interacting protein | -0.0336314 |
| RPS12 | ribosomal protein S12 | -0.0329881 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0327396 |
| RPS20 | ribosomal protein S20 | -0.0322114 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0322043 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0321118 |
| RPL12 | ribosomal protein L12 | -0.031449 |
| RPLP1 | ribosomal protein, large, P1 | -0.0313149 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0306604 |
| RPS24 | ribosomal protein S24 | -0.0302417 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0301973 |
| EGFR | epidermal growth factor receptor | -0.0298891 |
| USP34 | ubiquitin specific peptidase 34 | -0.029851 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0288731 |
| CNKSR3 | CNKSR family member 3 | -0.0288259 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0288236 |
| THOC2 | THO complex 2 | -0.0286789 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0283991 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0283777 |
| CCDC91 | coiled-coil domain containing 91 | -0.0281651 |
| RCOR1 | REST corepressor 1 | -0.0277722 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0277518 |
| RPL37A | ribosomal protein L37a | -0.0275439 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0269702 |
| RPS25 | ribosomal protein S25 | -0.0267298 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0266887 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0266502 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.026462 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0257367 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0255928 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0253796 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0252559 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0251891 |
| SBF2 | SET binding factor 2 | -0.0251738 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0251212 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0250935 |
| RPL19 | ribosomal protein L19 | -0.0250904 |
| NPTN | neuroplastin | -0.0250098 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0248316 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0245385 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0243583 |
| MAP7 | microtubule-associated protein 7 | -0.0241728 |
| ZNF217 | zinc finger protein 217 | -0.0239067 |
| RPL31 | ribosomal protein L31 | -0.0238714 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0237028 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0236043 |
| CSTB | cystatin B (stefin B) | -0.0235646 |
| IGF2 | insulin-like growth factor 2 | -0.023561 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0230465 |
| CDCP1 | CUB domain containing protein 1 | -0.0228825 |
