| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tranilast_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.118078 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.105011 |
| KIF5B | kinesin family member 5B | 0.0880395 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0839403 |
| PDE10A | phosphodiesterase 10A | 0.0836482 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0831143 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0828849 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0806781 |
| NKTR | natural killer cell triggering receptor | 0.0790642 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0763609 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0746465 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0727474 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0723314 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0708756 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.068728 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0676988 |
| FBXO11 | F-box protein 11 | 0.0650304 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0633942 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0626117 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.0608552 |
| CUX1 | cut-like homeobox 1 | 0.0604204 |
| COG5 | component of oligomeric golgi complex 5 | 0.0583653 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0558799 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0557789 |
| RPL26 | ribosomal protein L26 | 0.0543346 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0538605 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0537222 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.053395 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0530633 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0528247 |
| THOC2 | THO complex 2 | 0.0526685 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0516465 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0516364 |
| FUS | FUS RNA binding protein | 0.0512985 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0508918 |
| USP34 | ubiquitin specific peptidase 34 | 0.0502892 |
| SLC38A2 | solute carrier family 38, member 2 | 0.050163 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0498734 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0498576 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0494779 |
| HDLBP | high density lipoprotein binding protein | 0.0490498 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0486411 |
| MEF2A | myocyte enhancer factor 2A | 0.0482391 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0481372 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0469008 |
| OGA | O-GlcNAcase | 0.0466647 |
| PGK1 | phosphoglycerate kinase 1 | 0.0463321 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0462201 |
| MAP4 | microtubule-associated protein 4 | 0.0458583 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0456649 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0455957 |
| ATXN2 | ataxin 2 | 0.0454887 |
| SBF2 | SET binding factor 2 | 0.0453397 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0451528 |
| SGMS1 | sphingomyelin synthase 1 | 0.0450935 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0444071 |
| NCKAP1 | NCK-associated protein 1 | 0.0442423 |
| NPTN | neuroplastin | 0.044037 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0439194 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0438858 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0433455 |
| GPHN | gephyrin | 0.0430389 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0424396 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.040515 |
| FMNL2 | formin-like 2 | 0.0384484 |
| EFNA5 | ephrin-A5 | 0.0378811 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0369208 |
| TXNRD1 | thioredoxin reductase 1 | 0.0368412 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.036737 |
| CANX | calnexin | 0.0362279 |
| DSPP | dentin sialophosphoprotein | 0.0360051 |
| FOXO3 | forkhead box O3 | 0.0353957 |
| GPC6 | glypican 6 | 0.0348663 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0345932 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0344309 |
| MED13 | mediator complex subunit 13 | 0.0340201 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0339709 |
| CDC73 | cell division cycle 73 | 0.0332999 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0321327 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0321321 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0315581 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0313807 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0310419 |
| ADAR | adenosine deaminase, RNA-specific | 0.0305403 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0302852 |
| WDR45B | WD repeat domain 45B | 0.0300515 |
| MTDH | metadherin | 0.0298889 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0295438 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0294377 |
| AHNAK | AHNAK nucleoprotein | 0.0293835 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0291659 |
| SERINC1 | serine incorporator 1 | 0.0285706 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0282704 |
| LMNA | lamin A/C | 0.0281562 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0280486 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0278144 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0276079 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0274399 |
| RBM39 | RNA binding motif protein 39 | 0.0274236 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0273085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.192322 |
| PTMA | prothymosin, alpha | -0.142712 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134419 |
| TMSB10 | thymosin beta 10 | -0.116069 |
| FN1 | fibronectin 1 | -0.110325 |
| ASPH | aspartate beta-hydroxylase | -0.0882996 |
| EGFR | epidermal growth factor receptor | -0.0835325 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0818829 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0781348 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0727941 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0722013 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.071414 |
| RPS27A | ribosomal protein S27a | -0.0706794 |
| B2M | beta-2-microglobulin | -0.0693628 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0686654 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.06791 |
| RPLP2 | ribosomal protein, large, P2 | -0.0670765 |
| RPL34 | ribosomal protein L34 | -0.0649901 |
| SQSTM1 | sequestosome 1 | -0.0647682 |
| RPL36A | ribosomal protein L36a | -0.0641408 |
| MYO1E | myosin IE | -0.0631315 |
| ACTG1 | actin gamma 1 | -0.0614435 |
| HMGA2 | high mobility group AT-hook 2 | -0.0594871 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0582141 |
| RPL35A | ribosomal protein L35a | -0.0579679 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0577559 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0556399 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0543064 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0538505 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0533082 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0509072 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0507527 |
| RPS6 | ribosomal protein S6 | -0.0502221 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0501844 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0500952 |
| RPL27A | ribosomal protein L27a | -0.0498805 |
| ERBIN | erbb2 interacting protein | -0.0492869 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.04926 |
| RPLP1 | ribosomal protein, large, P1 | -0.0491954 |
| MED13L | mediator complex subunit 13-like | -0.0490887 |
| RTN4 | reticulon 4 | -0.048461 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0482806 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0482781 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0481051 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0477378 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0476571 |
| ENO1 | enolase 1, (alpha) | -0.0468947 |
| CDC27 | cell division cycle 27 | -0.0458267 |
| RACK1 | receptor for activated C kinase 1 | -0.0454933 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0454678 |
| GNAS | GNAS complex locus | -0.0454268 |
| AREG | amphiregulin | -0.0452231 |
| ITGA6 | integrin, alpha 6 | -0.0440442 |
| RPS29 | ribosomal protein S29 | -0.043591 |
| NDRG1 | N-myc downstream regulated 1 | -0.0434959 |
| ATP11A | ATPase, class VI, type 11A | -0.0416258 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0409723 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0406396 |
| FOXP1 | forkhead box P1 | -0.0402375 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0391884 |
| MT2A | metallothionein 2A | -0.0384133 |
| OSMR | oncostatin M receptor | -0.0377635 |
| RPLP0 | ribosomal protein, large, P0 | -0.0377232 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0375396 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0371353 |
| MORF4L2 | mortality factor 4 like 2 | -0.0371042 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0370865 |
| RPL23 | ribosomal protein L23 | -0.03701 |
| RPL37A | ribosomal protein L37a | -0.0367913 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0366984 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.036566 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0362926 |
| SLTM | SAFB-like, transcription modulator | -0.0360745 |
| ANXA2 | annexin A2 | -0.0357517 |
| DENND1A | DENN/MADD domain containing 1A | -0.0353451 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0352373 |
| PTK2 | protein tyrosine kinase 2 | -0.0343948 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0341792 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0339395 |
| RPS8 | ribosomal protein S8 | -0.0328781 |
| RPL15 | ribosomal protein L15 | -0.032662 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0324846 |
| NF1 | neurofibromin 1 | -0.0314199 |
| RFX7 | regulatory factor X, 7 | -0.0313068 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0310017 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0308832 |
| RPL12 | ribosomal protein L12 | -0.0307212 |
| RPS16 | ribosomal protein S16 | -0.0306546 |
| RSF1 | remodeling and spacing factor 1 | -0.0305788 |
| FOXJ3 | forkhead box J3 | -0.0302578 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0294691 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0294457 |
| GSE1 | Gse1 coiled-coil protein | -0.0288209 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0286523 |
| PDE8A | phosphodiesterase 8A | -0.0283192 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0282141 |
| PRKCA | protein kinase C, alpha | -0.0281791 |
| MYOF | myoferlin | -0.0281542 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.027767 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0274656 |
