| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tranilast_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.162727 |
| CADM2 | cell adhesion molecule 2 | 0.090067 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0663919 |
| NTM | neurotrimin | 0.0544588 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0531753 |
| ITGAV | integrin, alpha V | 0.0499389 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0490106 |
| LRRC4C | leucine rich repeat containing 4C | 0.0466844 |
| VIM | vimentin | 0.0446623 |
| DST | dystonin | 0.0427926 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.04252 |
| HMCN1 | hemicentin 1 | 0.0381132 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0378464 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0365819 |
| RPS8 | ribosomal protein S8 | 0.0363329 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0361233 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0357013 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0336892 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0328178 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0327854 |
| NEBL | nebulette | 0.030681 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0306479 |
| RPS16 | ribosomal protein S16 | 0.0292968 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0291973 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0287375 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0287365 |
| UPP1 | uridine phosphorylase 1 | 0.0287046 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0285952 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0283785 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0275305 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0272424 |
| PHIP | pleckstrin homology domain interacting protein | 0.026962 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0264467 |
| RPS12 | ribosomal protein S12 | 0.0260789 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0259798 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0256446 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0252148 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0242147 |
| RPS6 | ribosomal protein S6 | 0.023788 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0236833 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0236104 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0232492 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0232479 |
| FMNL2 | formin-like 2 | 0.0230831 |
| RDX | radixin | 0.0228178 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0225232 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0223386 |
| PRTG | protogenin | 0.0220892 |
| JMJD1C | jumonji domain containing 1C | 0.0217518 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0215865 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0212353 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0212141 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0208714 |
| WASF2 | WAS protein family, member 2 | 0.020816 |
| FBXO17 | F-box protein 17 | 0.0207973 |
| SNX6 | sorting nexin 6 | 0.020639 |
| TPM3 | tropomyosin 3 | 0.0206175 |
| MAP4 | microtubule-associated protein 4 | 0.0205437 |
| TENM3 | teneurin transmembrane protein 3 | 0.0204939 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0204652 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0203969 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0203482 |
| CUX1 | cut-like homeobox 1 | 0.0203411 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0203304 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0199198 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0198874 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0197512 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0196284 |
| CFL2 | cofilin 2 (muscle) | 0.0196009 |
| RTN4 | reticulon 4 | 0.0195164 |
| KIF13A | kinesin family member 13A | 0.0194595 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0193062 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0192453 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0192126 |
| VMP1 | vacuole membrane protein 1 | 0.0191455 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0191089 |
| SNX3 | sorting nexin 3 | 0.0188537 |
| APOE | apolipoprotein E | 0.0187095 |
| SET | SET nuclear proto-oncogene | 0.0186619 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0186425 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0183609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0181984 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0181955 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0181932 |
| ETV1 | ets variant 1 | 0.0180667 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0180658 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0180631 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0179483 |
| FGF13 | fibroblast growth factor 13 | 0.0178204 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0177389 |
| SFTPA2 | surfactant protein A2 | 0.0176748 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0176358 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0175486 |
| CCN2 | cellular communication network factor 2 | 0.0175024 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0174374 |
| PCDH9 | protocadherin 9 | 0.0174287 |
| MCL1 | myeloid cell leukemia 1 | 0.0173982 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0173471 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0173213 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0171068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.106049 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0745455 |
| CENPF | centromere protein F, 350/400kDa | -0.0534447 |
| ZNF292 | zinc finger protein 292 | -0.0421642 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0417146 |
| GPC3 | glypican 3 | -0.040755 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0404158 |
| MKI67 | marker of proliferation Ki-67 | -0.0389693 |
| PEG10 | paternally expressed 10 | -0.037679 |
| FOXP2 | forkhead box P2 | -0.0376471 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0368727 |
| CENPE | centromere protein E, 312kDa | -0.0362248 |
| KIF4A | kinesin family member 4A | -0.0355588 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0348592 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0334374 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0330845 |
| MED13L | mediator complex subunit 13-like | -0.0329635 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.03196 |
| RPS3 | ribosomal protein S3 | -0.0312012 |
| SGO2 | shugoshin 2 | -0.0282914 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0282895 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0273149 |
| SMC4 | structural maintenance of chromosomes 4 | -0.027199 |
| RLF | rearranged L-myc fusion | -0.0271314 |
| TPX2 | TPX2, microtubule-associated | -0.026461 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0263971 |
| FIGN | fidgetin | -0.0263742 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0263493 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0258732 |
| ANLN | anillin, actin binding protein | -0.0255517 |
| BBX | bobby sox homolog (Drosophila) | -0.0254545 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0244 |
| PRKD1 | protein kinase D1 | -0.0226356 |
| ZNF385D | zinc finger protein 385D | -0.022595 |
| HMGB2 | high mobility group box 2 | -0.0215072 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0212502 |
| MTF2 | metal response element binding transcription factor 2 | -0.0209382 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0205825 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0203433 |
| USP3 | ubiquitin specific peptidase 3 | -0.0199306 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0196052 |
| ABI2 | abl-interactor 2 | -0.019463 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0193852 |
| ACTG1 | actin gamma 1 | -0.0191681 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0191643 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.019103 |
| KIF2C | kinesin family member 2C | -0.0190026 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0187676 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0186306 |
| PRR11 | proline rich 11 | -0.0182887 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0181508 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0181116 |
| ANXA2 | annexin A2 | -0.0180728 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0177593 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0175693 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0172186 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0171855 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0171835 |
| GOLGA4 | golgin A4 | -0.017073 |
| PHF3 | PHD finger protein 3 | -0.0169129 |
| PDGFC | platelet derived growth factor C | -0.0168385 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0168297 |
| H2AZ2 | H2A.Z variant histone 2 | -0.0167795 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0161356 |
| YAP1 | Yes-associated protein 1 | -0.0161234 |
| FBXO11 | F-box protein 11 | -0.0160193 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0160071 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0158623 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.015699 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0154189 |
| TRERF1 | transcriptional regulating factor 1 | -0.0154084 |
| CEP350 | centrosomal protein 350kDa | -0.015366 |
| CDC73 | cell division cycle 73 | -0.0152368 |
| WDR70 | WD repeat domain 70 | -0.0151884 |
| MEMO1 | mediator of cell motility 1 | -0.0151691 |
| ECT2 | epithelial cell transforming 2 | -0.0150527 |
| PTK2 | protein tyrosine kinase 2 | -0.0148083 |
| TTK | TTK protein kinase | -0.0147749 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0147672 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0147637 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0147331 |
| RPL19 | ribosomal protein L19 | -0.0145194 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0144951 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0144932 |
| ZNF217 | zinc finger protein 217 | -0.014412 |
| FTL | ferritin, light polypeptide | -0.014391 |
| TPI1 | triosephosphate isomerase 1 | -0.0141186 |
| DIAPH3 | diaphanous-related formin 3 | -0.0139964 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | -0.0139161 |
| USP22 | ubiquitin specific peptidase 22 | -0.013859 |
| RTN3 | reticulon 3 | -0.0138498 |
| RPLP1 | ribosomal protein, large, P1 | -0.0137218 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | -0.0137124 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0136806 |
| TUBA1B | tubulin, alpha 1b | -0.0135378 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0134801 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0134486 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0134257 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0133965 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0133727 |
