| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tranilast perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tranilast_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.174603 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.129277 |
| TXNRD1 | thioredoxin reductase 1 | 0.106437 |
| EZR | ezrin | 0.0949405 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0883281 |
| AHNAK | AHNAK nucleoprotein | 0.0868002 |
| EGFR | epidermal growth factor receptor | 0.0851985 |
| FLNB | filamin B, beta | 0.0687884 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0665648 |
| S100A6 | S100 calcium binding protein A6 | 0.0572659 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0557368 |
| NBEA | neurobeachin | 0.0519281 |
| RTN4 | reticulon 4 | 0.0512678 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0499823 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0493206 |
| PRELID2 | PRELI domain containing 2 | 0.0469633 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0469481 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0468669 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0461386 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0437506 |
| ATP9B | ATPase, class II, type 9B | 0.0435149 |
| LDHA | lactate dehydrogenase A | 0.0427234 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0425557 |
| SRPK2 | SRSF protein kinase 2 | 0.0416754 |
| PKM | pyruvate kinase, muscle | 0.0416073 |
| EFNA5 | ephrin-A5 | 0.0411139 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0409134 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0406503 |
| RBM39 | RNA binding motif protein 39 | 0.0395113 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0394373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.039363 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0391044 |
| TMEM41B | transmembrane protein 41B | 0.0383506 |
| CLTC | clathrin, heavy chain (Hc) | 0.0379877 |
| POTEF | POTE ankyrin domain family, member F | 0.037624 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0370204 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0361169 |
| PYGB | phosphorylase, glycogen; brain | 0.0355093 |
| ECT2 | epithelial cell transforming 2 | 0.0349076 |
| DSTN | destrin (actin depolymerizing factor) | 0.0344768 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0340595 |
| ANK2 | ankyrin 2, neuronal | 0.0340243 |
| ENO1 | enolase 1, (alpha) | 0.0339362 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0332465 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0331988 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0329036 |
| TMEM65 | transmembrane protein 65 | 0.0327936 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0322044 |
| CD47 | CD47 molecule | 0.0320361 |
| VCL | vinculin | 0.0320311 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.031716 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0317057 |
| RNF145 | ring finger protein 145 | 0.0315596 |
| TJP1 | tight junction protein 1 | 0.0315167 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0313216 |
| TMSB4X | thymosin beta 4, X-linked | 0.0312203 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0306327 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0303292 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0302905 |
| JMJD1C | jumonji domain containing 1C | 0.0300705 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0296447 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0295992 |
| METTL15 | methyltransferase like 15 | 0.0294233 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0291632 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 0.028528 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0285126 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0282453 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0277851 |
| ZNF292 | zinc finger protein 292 | 0.0275375 |
| NUP58 | nucleoporin 58 | 0.0274842 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0272176 |
| GOLGA4 | golgin A4 | 0.0271731 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0270597 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0267238 |
| COG5 | component of oligomeric golgi complex 5 | 0.0262643 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0261233 |
| BRD2 | bromodomain containing 2 | 0.026056 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0259115 |
| SON | SON DNA binding protein | 0.0252116 |
| SBF2 | SET binding factor 2 | 0.0248002 |
| PLK2 | polo-like kinase 2 | 0.0245875 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0245103 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0243197 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0241149 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0239837 |
| TCF12 | transcription factor 12 | 0.0239404 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0237011 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0236999 |
| MAP4 | microtubule-associated protein 4 | 0.023675 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0236442 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0236441 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0235597 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0235444 |
| ARRDC3 | arrestin domain containing 3 | 0.023286 |
| COG6 | component of oligomeric golgi complex 6 | 0.0232826 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0232786 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0228891 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0228789 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0227274 |
| CCNL1 | cyclin L1 | 0.0226238 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.159737 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.105482 |
| RPS8 | ribosomal protein S8 | -0.0787655 |
| RPS6 | ribosomal protein S6 | -0.0760136 |
| RPL35A | ribosomal protein L35a | -0.0749838 |
| BMP10 | bone morphogenetic protein 10 | -0.0607873 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0598325 |
| RPL37A | ribosomal protein L37a | -0.0592619 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0545766 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0531723 |
| RPL34 | ribosomal protein L34 | -0.049795 |
| RPLP2 | ribosomal protein, large, P2 | -0.0484388 |
| RPL26 | ribosomal protein L26 | -0.0466458 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0455297 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.044289 |
| RPS27A | ribosomal protein S27a | -0.0439402 |
| RPL31 | ribosomal protein L31 | -0.0438724 |
| RPS3 | ribosomal protein S3 | -0.0424304 |
| BMP2K | BMP2 inducible kinase | -0.0417258 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0403081 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0385543 |
| RPS12 | ribosomal protein S12 | -0.0382206 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.036046 |
| RPL9 | ribosomal protein L9 | -0.0354382 |
| NAV2 | neuron navigator 2 | -0.0352998 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.035207 |
| RPL13A | ribosomal protein L13a | -0.0344649 |
| RPL12 | ribosomal protein L12 | -0.0337986 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0323181 |
| RPL30 | ribosomal protein L30 | -0.0322959 |
| RACK1 | receptor for activated C kinase 1 | -0.0314577 |
| RPL11 | ribosomal protein L11 | -0.031323 |
| RPL19 | ribosomal protein L19 | -0.0312846 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0310643 |
| RPL7A | ribosomal protein L7a | -0.0309995 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0302623 |
| MYOF | myoferlin | -0.0302404 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0292138 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0291571 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0277267 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0276218 |
| RPS10 | ribosomal protein S10 | -0.0270423 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0270086 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0269443 |
| RPS19 | ribosomal protein S19 | -0.0263784 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0260924 |
| RPL23 | ribosomal protein L23 | -0.0259721 |
| GNAS | GNAS complex locus | -0.0259679 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259513 |
| RPL5 | ribosomal protein L5 | -0.0259113 |
| RPS27 | ribosomal protein S27 | -0.0252853 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0252681 |
| BCOR | BCL6 corepressor | -0.0251291 |
| RPL38 | ribosomal protein L38 | -0.0251206 |
| RPLP0 | ribosomal protein, large, P0 | -0.0245679 |
| FN1 | fibronectin 1 | -0.0240286 |
| NPAS2 | neuronal PAS domain protein 2 | -0.023945 |
| RPS13 | ribosomal protein S13 | -0.0238395 |
| RPS17 | ribosomal protein S17 | -0.0236608 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0233516 |
| CUX1 | cut-like homeobox 1 | -0.0226627 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0222844 |
| INHBA | inhibin, beta A | -0.0220061 |
| RPS24 | ribosomal protein S24 | -0.0218616 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0218569 |
| ACTG1 | actin gamma 1 | -0.0217422 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0215 |
| PGK1 | phosphoglycerate kinase 1 | -0.0213766 |
| RPL36A | ribosomal protein L36a | -0.0208574 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0207238 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0206698 |
| RPS23 | ribosomal protein S23 | -0.020559 |
| RPS25 | ribosomal protein S25 | -0.0202134 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0201556 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0196498 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0196089 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0194431 |
| TMSB10 | thymosin beta 10 | -0.0192454 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0187379 |
| IRX2 | iroquois homeobox 2 | -0.0182953 |
| GTF2I | general transcription factor IIi | -0.0182347 |
| RPL8 | ribosomal protein L8 | -0.0177301 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0177053 |
| UBB | ubiquitin B | -0.0177053 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0175626 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0175514 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0174577 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0172319 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0167299 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0167062 |
| TPI1 | triosephosphate isomerase 1 | -0.0166536 |
| FOXP1 | forkhead box P1 | -0.0165891 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0165871 |
| RPL37 | ribosomal protein L37 | -0.0165438 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0164951 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0164882 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.016429 |
| VIM | vimentin | -0.0163622 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0163526 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0163353 |
