Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-2173793
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Genes

51 proteins participating in the Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
CCNC cyclin C
CCNK cyclin K
CCNT1 cyclin T1
CCNT2 cyclin T2
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
COL1A2 collagen, type I, alpha 2
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
EP300 E1A binding protein p300
FURIN furin (paired basic amino acid cleaving enzyme)
HDAC1 histone deacetylase 1
JUNB jun B proto-oncogene
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MEN1 multiple endocrine neoplasia I
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
RBL1 retinoblastoma-like 1
RNF111 ring finger protein 111
RPS27A ribosomal protein S27a
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNW1 SNW domain containing 1
SP1 Sp1 transcription factor
STAT1 signal transducer and activator of transcription 1, 91kDa
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGIF1 TGFB-induced factor homeobox 1
TGIF2 TGFB-induced factor homeobox 2
TRIM33 tripartite motif containing 33
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D3 ubiquitin-conjugating enzyme E2D 3
USP9X ubiquitin specific peptidase 9, X-linked
WWTR1 WW domain containing transcription regulator 1
YBX1 Y box binding protein 1