Transcriptional regulation by RUNX2 Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-8878166
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Genes

106 proteins participating in the Transcriptional regulation by RUNX2 pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADRM1 adhesion regulating molecule 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
AR androgen receptor
BAX BCL2-associated X protein
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP2 bone morphogenetic protein 2
CBFB core-binding factor, beta subunit
CCNB1 cyclin B1
CCND1 cyclin D1
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL1A1 collagen, type I, alpha 1
CUL1 cullin 1
DLX5 distal-less homeobox 5
DLX6 distal-less homeobox 6
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GSK3B glycogen synthase kinase 3 beta
HAND2 heart and neural crest derivatives expressed 2
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC6 histone deacetylase 6
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IHH indian hedgehog
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LGALS3 lectin, galactoside-binding, soluble, 3
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MMP13 matrix metallopeptidase 13
MSX2 msh homeobox 2
NKX3-2 NK3 homeobox 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
RB1 retinoblastoma 1
RBM14 RNA binding motif protein 14
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SATB2 SATB homeobox 2
SEM1 SEM1 26S proteasome subunit
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMAD1 SMAD family member 1
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SOX9 SRY (sex determining region Y)-box 9
SP7 Sp7 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TWIST1 twist family bHLH transcription factor 1
TWIST2 twist family bHLH transcription factor 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UCMA upper zone of growth plate and cartilage matrix associated
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWTR1 WW domain containing transcription regulator 1
YAP1 Yes-associated protein 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZNF521 zinc finger protein 521