Transplanted Heart Complication_Myocardial tissue_GSE582 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE582
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Genes

600 genes differentially expressed during Transplanted Heart Complication_Myocardial tissue_GSE582 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 5.08738
RNH1 ribonuclease/angiogenin inhibitor 1 4.15365
ACSL4 acyl-CoA synthetase long-chain family member 4 4.07626
USP6NL USP6 N-terminal like 3.8108
MYO1F myosin IF 3.5971
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 3.32493
SGPL1 sphingosine-1-phosphate lyase 1 3.26654
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 3.209
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 3.17
SF3A1 splicing factor 3a, subunit 1, 120kDa 3.16307
RRP1B ribosomal RNA processing 1B 3.10042
COPB1 coatomer protein complex, subunit beta 1 3.0751
HAX1 HCLS1 associated protein X-1 3.01142
SFR1 SWI5-dependent recombination repair 1 2.94582
GSK3A glycogen synthase kinase 3 alpha 2.91589
SCPEP1 serine carboxypeptidase 1 2.89773
PRDX5 peroxiredoxin 5 2.82983
SLC16A6 solute carrier family 16, member 6 2.77473
RSL1D1 ribosomal L1 domain containing 1 2.77061
PUF60 poly-U binding splicing factor 60KDa 2.76301
FTH1 ferritin, heavy polypeptide 1 2.69117
BECN1 beclin 1, autophagy related 2.66342
UBQLN1 ubiquilin 1 2.64192
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.6199
CDC25C cell division cycle 25C 2.59794
AK2 adenylate kinase 2 2.57994
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.5697
PHF23 PHD finger protein 23 2.56379
MERTK MER proto-oncogene, tyrosine kinase 2.56318
UBE2K ubiquitin-conjugating enzyme E2K 2.54652
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 2.53657
CTSZ cathepsin Z 2.53601
TIPRL TOR signaling pathway regulator 2.45027
RPN1 ribophorin I 2.42081
KIAA1191 KIAA1191 2.39588
EIF6 eukaryotic translation initiation factor 6 2.38198
RPL6 ribosomal protein L6 2.37909
PELO pelota homolog (Drosophila) 2.37311
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.36187
VARS valyl-tRNA synthetase 2.36004
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.35614
CCAR1 cell division cycle and apoptosis regulator 1 2.34864
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.2973
TARS threonyl-tRNA synthetase 2.29592
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 2.28776
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 2.2876
TMEM11 transmembrane protein 11 2.28099
ADRBK1 adrenergic, beta, receptor kinase 1 2.26947
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 2.26329
ETHE1 ethylmalonic encephalopathy 1 2.25521
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.25239
TXNRD1 thioredoxin reductase 1 2.23852
BCAP31 B-cell receptor-associated protein 31 2.23573
USP10 ubiquitin specific peptidase 10 2.23177
TALDO1 transaldolase 1 2.20424
LDHA lactate dehydrogenase A 2.2034
CDK4 cyclin-dependent kinase 4 2.20249
BTG1 B-cell translocation gene 1, anti-proliferative 2.20198
PDCD6 programmed cell death 6 2.17935
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.17841
RPL21 ribosomal protein L21 2.17457
EMC8 ER membrane protein complex subunit 8 2.17348
PRKCSH protein kinase C substrate 80K-H 2.17333
VTI1B vesicle transport through interaction with t-SNAREs 1B 2.17297
CHD7 chromodomain helicase DNA binding protein 7 2.16623
LGALS3 lectin, galactoside-binding, soluble, 3 2.15494
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.13899
CLK3 CDC-like kinase 3 2.13452
SMAP2 small ArfGAP2 2.13419
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.12532
DTYMK deoxythymidylate kinase (thymidylate kinase) 2.12259
WDR26 WD repeat domain 26 2.11554
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.10046
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.06939
GLRX glutaredoxin (thioltransferase) 2.04397
GCH1 GTP cyclohydrolase 1 2.04256
HPCAL1 hippocalcin-like 1 2.03688
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2.03657
ARF1 ADP-ribosylation factor 1 2.03159
EZR ezrin 2.00541
LRRC59 leucine rich repeat containing 59 1.99779
ARHGAP1 Rho GTPase activating protein 1 1.98342
MXI1 MAX interactor 1, dimerization protein 1.98121
MARS methionyl-tRNA synthetase 1.9658
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.96309
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 1.94971
RAB10 RAB10, member RAS oncogene family 1.94881
GSR glutathione reductase 1.9449
DGCR2 DiGeorge syndrome critical region gene 2 1.9189
GNPDA1 glucosamine-6-phosphate deaminase 1 1.91118
IL11 interleukin 11 1.90492
PGK1 phosphoglycerate kinase 1 1.89974
CLK2 CDC-like kinase 2 1.89908
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 1.89339
RUNX2 runt-related transcription factor 2 1.89296
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.89169
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.88603
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 1.88325
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 1.87855
EDN1 endothelin 1 1.85475
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.84446
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.841
ADAM10 ADAM metallopeptidase domain 10 1.83418
SNX4 sorting nexin 4 1.82561
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 1.82012
RPS2 ribosomal protein S2 1.81699
TSSC4 tumor suppressing subtransferable candidate 4 1.81425
MTPN myotrophin 1.81332
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 1.80307
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 1.79773
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.79686
GRB2 growth factor receptor-bound protein 2 1.79332
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 1.78797
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 1.78589
SEC61G Sec61 gamma subunit 1.77603
RPL24 ribosomal protein L24 1.77364
STXBP1 syntaxin binding protein 1 1.77024
PGAM1 phosphoglycerate mutase 1 (brain) 1.76884
RP1L1 retinitis pigmentosa 1-like 1 1.76487
RPL7A ribosomal protein L7a 1.75938
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.75797
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 1.74796
RGS16 regulator of G-protein signaling 16 1.74495
C3ORF38 chromosome 3 open reading frame 38 1.74346
MRPS18B mitochondrial ribosomal protein S18B 1.74154
RBM42 RNA binding motif protein 42 1.74066
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.73349
UPP1 uridine phosphorylase 1 1.72598
NEU1 sialidase 1 (lysosomal sialidase) 1.72573
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.72543
TMEM30A transmembrane protein 30A 1.71087
TBK1 TANK-binding kinase 1 1.70476
FUBP1 far upstream element (FUSE) binding protein 1 1.69845
CLP1 cleavage and polyadenylation factor I subunit 1 1.69837
NFIL3 nuclear factor, interleukin 3 regulated 1.69705
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.69502
TXN thioredoxin 1.68333
FNBP4 formin binding protein 4 1.68331
MAN2B1 mannosidase, alpha, class 2B, member 1 1.68007
SIN3B SIN3 transcription regulator family member B 1.67972
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 1.67944
MTMR9 myotubularin related protein 9 1.6724
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1.67129
DDA1 DET1 and DDB1 associated 1 1.67078
MED23 mediator complex subunit 23 1.67043
UBA5 ubiquitin-like modifier activating enzyme 5 1.66959
RALY RALY heterogeneous nuclear ribonucleoprotein 1.66457
ZIC4 Zic family member 4 1.66451
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.65955
HTT huntingtin 1.65755
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.65337
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.6504
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.64901
RBM8A RNA binding motif protein 8A 1.64677
NAMPT nicotinamide phosphoribosyltransferase 1.64389
TMEM14C transmembrane protein 14C 1.6403
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.63799
ACTG1 actin gamma 1 1.63679
USP34 ubiquitin specific peptidase 34 1.63321
C6ORF62 chromosome 6 open reading frame 62 1.63161
ZNF326 zinc finger protein 326 1.62725
TTC4 tetratricopeptide repeat domain 4 1.62282
FGR FGR proto-oncogene, Src family tyrosine kinase 1.61986
METTL1 methyltransferase like 1 1.61647
NSD1 nuclear receptor binding SET domain protein 1 1.61406
SUSD6 sushi domain containing 6 1.60782
SRM spermidine synthase 1.60693
ESD esterase D 1.60384
ALLC allantoicase 1.60328
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.58648
CRELD2 cysteine-rich with EGF-like domains 2 1.58615
CTBP1 C-terminal binding protein 1 1.58384
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 1.57889
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.57804
MAPK6 mitogen-activated protein kinase 6 1.57613
TBC1D21 TBC1 domain family, member 21 1.55936
RPL5 ribosomal protein L5 1.55847
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.55467
HCRT hypocretin (orexin) neuropeptide precursor 1.55436
PARP2 poly (ADP-ribose) polymerase 2 1.55413
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.5496
CSTB cystatin B (stefin B) 1.5474
PEX13 peroxisomal biogenesis factor 13 1.54026
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.53947
CDAN1 codanin 1 1.53696
UBAP2 ubiquitin associated protein 2 1.53511
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.5296
PDCD6IP programmed cell death 6 interacting protein 1.52776
ATXN7L3 ataxin 7-like 3 1.51923
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 1.51289
SLC44A2 solute carrier family 44 (choline transporter), member 2 1.51052
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 1.50861
FAM32A family with sequence similarity 32, member A 1.50355
LZTFL1 leucine zipper transcription factor-like 1 1.49381
USP3 ubiquitin specific peptidase 3 1.49158
ZNF703 zinc finger protein 703 1.48175
PPP1R7 protein phosphatase 1, regulatory subunit 7 1.48005
MCM5 minichromosome maintenance complex component 5 1.47677
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.47494
PDE4B phosphodiesterase 4B, cAMP-specific 1.47251
PCBP2 poly(rC) binding protein 2 1.47115
ACTL6A actin-like 6A 1.46965
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.468
TRAF3IP2 TRAF3 interacting protein 2 1.46385
FKBP2 FK506 binding protein 2, 13kDa 1.46049
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.4577
CTSA cathepsin A 1.45357
N4BP1 NEDD4 binding protein 1 1.44543
PRELID1 PRELI domain containing 1 1.44029
ACOT7 acyl-CoA thioesterase 7 1.43941
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 1.43503
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.43439
NCAPH2 non-SMC condensin II complex, subunit H2 1.43233
TPI1 triosephosphate isomerase 1 1.42542
BAX BCL2-associated X protein 1.42453
SCAND1 SCAN domain containing 1 1.42121
XPO6 exportin 6 1.42028
ZCCHC7 zinc finger, CCHC domain containing 7 1.41982
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.4186
RNPS1 RNA binding protein S1, serine-rich domain 1.41723
PPT2 palmitoyl-protein thioesterase 2 1.40883
RPN2 ribophorin II 1.40768
RAP1A RAP1A, member of RAS oncogene family 1.40528
PPP1R15B protein phosphatase 1, regulatory subunit 15B 1.4039
PKM pyruvate kinase, muscle 1.4033
MTM1 myotubularin 1 1.39963
PRDX1 peroxiredoxin 1 1.39806
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 1.3917
ZNF239 zinc finger protein 239 1.39074
MMP7 matrix metallopeptidase 7 1.3906
CXORF38 chromosome X open reading frame 38 1.38756
SMAD2 SMAD family member 2 1.38727
MRPS14 mitochondrial ribosomal protein S14 1.38576
MOGS mannosyl-oligosaccharide glucosidase 1.38395
RAB3A RAB3A, member RAS oncogene family 1.38304
NPEPPS aminopeptidase puromycin sensitive 1.38165
WTAP Wilms tumor 1 associated protein 1.3813
TLX2 T-cell leukemia homeobox 2 1.38069
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 1.37865
AK4 adenylate kinase 4 1.37839
NCOR2 nuclear receptor corepressor 2 1.378
TBXAS1 thromboxane A synthase 1 (platelet) 1.37611
RPS28 ribosomal protein S28 1.37597
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.37566
RPL7 ribosomal protein L7 1.36945
MPP1 membrane protein, palmitoylated 1, 55kDa 1.36926
ERP29 endoplasmic reticulum protein 29 1.3545
TPD52 tumor protein D52 1.35269
ERO1L ERO1-like (S. cerevisiae) 1.3524
LOC81691 exonuclease NEF-sp 1.34495
RUVBL2 RuvB-like AAA ATPase 2 1.34479
WDR1 WD repeat domain 1 1.33614
ACTN4 actinin, alpha 4 1.33437
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 1.33327
SEC23B Sec23 homolog B (S. cerevisiae) 1.33266
BOP1 block of proliferation 1 1.33222
POFUT2 protein O-fucosyltransferase 2 1.33169
AGFG1 ArfGAP with FG repeats 1 1.32946
G6PD glucose-6-phosphate dehydrogenase 1.32934
THOC3 THO complex 3 1.32913
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.32838
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1.32828
WSB2 WD repeat and SOCS box containing 2 1.32599
RAE1 ribonucleic acid export 1 1.32316
TRAPPC4 trafficking protein particle complex 4 1.32258
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.32229
PCDHB11 protocadherin beta 11 1.32185
MRPS7 mitochondrial ribosomal protein S7 1.31982
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.31587
SYS1 Sys1 golgi trafficking protein 1.31469
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.31272
THUMPD1 THUMP domain containing 1 1.31236
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.30568
TRPV2 transient receptor potential cation channel, subfamily V, member 2 1.30151
RAN RAN, member RAS oncogene family 1.29895
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.2988
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.29731
TMEM97 transmembrane protein 97 1.29481
MTMR7 myotubularin related protein 7 1.29459
SEC24C SEC24 family member C 1.29362
DNASE1L1 deoxyribonuclease I-like 1 1.29312
CD164 CD164 molecule, sialomucin 1.29236
NDRG1 N-myc downstream regulated 1 1.28894
KLK8 kallikrein-related peptidase 8 1.28869
BAK1 BCL2-antagonist/killer 1 1.28738
PROCR protein C receptor, endothelial 1.28628
MSR1 macrophage scavenger receptor 1 1.2836
CDC42SE1 CDC42 small effector 1 1.2836
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.28312
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 1.28241
CNOT8 CCR4-NOT transcription complex, subunit 8 1.28059
RGS14 regulator of G-protein signaling 14 1.28055
DRG1 developmentally regulated GTP binding protein 1 1.28035
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.27772
GCLC glutamate-cysteine ligase, catalytic subunit 1.27734
C1ORF158 chromosome 1 open reading frame 158 1.27544
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 1.27522
CYFIP1 cytoplasmic FMR1 interacting protein 1 1.27084
TXNDC9 thioredoxin domain containing 9 1.27
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.26825

decreased expression

Symbol Name Standardized Value
SMO smoothened, frizzled class receptor -3.64242
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -3.38378
SBF2 SET binding factor 2 -3.34098
LYRM2 LYR motif containing 2 -3.31876
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -3.27584
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -3.11576
SPTSSA serine palmitoyltransferase, small subunit A -3.07767
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -3.0626
RNF11 ring finger protein 11 -3.01552
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -2.97111
RAB3D RAB3D, member RAS oncogene family -2.96112
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.93151
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.83777
MRPS31 mitochondrial ribosomal protein S31 -2.71071
BRD8 bromodomain containing 8 -2.67119
SERF2 small EDRK-rich factor 2 -2.5056
SCN1B sodium channel, voltage gated, type I beta subunit -2.449
GPAM glycerol-3-phosphate acyltransferase, mitochondrial -2.44507
SPARCL1 SPARC-like 1 (hevin) -2.41333
IL6ST interleukin 6 signal transducer -2.37487
RPL22 ribosomal protein L22 -2.36607
SFXN4 sideroflexin 4 -2.34183
PRKACB protein kinase, cAMP-dependent, catalytic, beta -2.28954
FBXW4 F-box and WD repeat domain containing 4 -2.28924
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.27793
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -2.238
CANX calnexin -2.22708
KDR kinase insert domain receptor -2.22436
CD81 CD81 molecule -2.21401
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K -2.18909
CTSF cathepsin F -2.16599
NAGK N-acetylglucosamine kinase -2.15958
C12ORF57 chromosome 12 open reading frame 57 -2.15248
CFH complement factor H -2.14999
GOLGA3 golgin A3 -2.13326
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.11545
EMC10 ER membrane protein complex subunit 10 -2.11233
ZEB1 zinc finger E-box binding homeobox 1 -2.09671
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.08123
OSBPL1A oxysterol binding protein-like 1A -2.06206
SSBP2 single-stranded DNA binding protein 2 -2.05966
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.04023
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -2.04
EI24 etoposide induced 2.4 -2.03999
CD99L2 CD99 molecule-like 2 -2.00935
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.00039
WBP1 WW domain binding protein 1 -1.99685
KLHL9 kelch-like family member 9 -1.99634
CLTC clathrin, heavy chain (Hc) -1.99311
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -1.97501
ZNF106 zinc finger protein 106 -1.97453
GSTZ1 glutathione S-transferase zeta 1 -1.96314
ADARB1 adenosine deaminase, RNA-specific, B1 -1.9623
LENG9 leukocyte receptor cluster (LRC) member 9 -1.9415
LUM lumican -1.92303
EBF3 early B-cell factor 3 -1.90881
DCN decorin -1.90824
STK40 serine/threonine kinase 40 -1.89516
TMEM150A transmembrane protein 150A -1.89053
GFER growth factor, augmenter of liver regeneration -1.88038
NFE2L1 nuclear factor, erythroid 2-like 1 -1.8802
LTBP4 latent transforming growth factor beta binding protein 4 -1.8723
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 -1.85764
C3 complement component 3 -1.85006
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -1.84108
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -1.83126
IGSF10 immunoglobulin superfamily, member 10 -1.80737
NOTCH3 notch 3 -1.80116
SOD3 superoxide dismutase 3, extracellular -1.79876
TMEM205 transmembrane protein 205 -1.79177
SDHAF1 succinate dehydrogenase complex assembly factor 1 -1.7898
ICA1 islet cell autoantigen 1, 69kDa -1.78448
GAS6 growth arrest-specific 6 -1.78186
ANKRD46 ankyrin repeat domain 46 -1.77692
TTC30B tetratricopeptide repeat domain 30B -1.76616
C1R complement component 1, r subcomponent -1.75844
CST3 cystatin C -1.75146
RNGTT RNA guanylyltransferase and 5'-phosphatase -1.74617
RABAC1 Rab acceptor 1 (prenylated) -1.74466
TBCK TBC1 domain containing kinase -1.7358
BMP6 bone morphogenetic protein 6 -1.7291
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -1.72773
SNRK SNF related kinase -1.72762
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -1.72501
RNMTL1 RNA methyltransferase like 1 -1.72377
PIGR polymeric immunoglobulin receptor -1.72298
UNC50 unc-50 homolog (C. elegans) -1.71468
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -1.71371
PNRC2 proline-rich nuclear receptor coactivator 2 -1.70415
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -1.7033
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -1.70009
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -1.69727
SELK selenoprotein K -1.69554
EIF3K eukaryotic translation initiation factor 3, subunit K -1.68683
KCTD20 potassium channel tetramerization domain containing 20 -1.68018
MYO6 myosin VI -1.6724
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -1.67162
RNF141 ring finger protein 141 -1.66075
TXNDC16 thioredoxin domain containing 16 -1.65328
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -1.64789
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -1.63372
YPEL3 yippee-like 3 (Drosophila) -1.62896
TCF12 transcription factor 12 -1.605
FABP4 fatty acid binding protein 4, adipocyte -1.60162
MRPL3 mitochondrial ribosomal protein L3 -1.59817
WNT6 wingless-type MMTV integration site family, member 6 -1.59321
MXD4 MAX dimerization protein 4 -1.58899
NPDC1 neural proliferation, differentiation and control, 1 -1.58115
COL14A1 collagen, type XIV, alpha 1 -1.57918
GPC4 glypican 4 -1.57554
BET1 Bet1 golgi vesicular membrane trafficking protein -1.57291
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -1.56698
RNF167 ring finger protein 167 -1.56656
PCOLCE procollagen C-endopeptidase enhancer -1.56566
MSLN mesothelin -1.56305
TMEM176B transmembrane protein 176B -1.55746
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -1.55624
ATRAID all-trans retinoic acid-induced differentiation factor -1.54827
HIST1H3C histone cluster 1, H3c -1.53022
C14ORF1 chromosome 14 open reading frame 1 -1.53019
PDCL3 phosducin-like 3 -1.52799
CYB561 cytochrome b561 -1.5227
ZNF644 zinc finger protein 644 -1.51678
SMAGP small cell adhesion glycoprotein -1.51545
GUK1 guanylate kinase 1 -1.51239
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 -1.51082
ANXA6 annexin A6 -1.49922
SCMH1 sex comb on midleg homolog 1 (Drosophila) -1.49671
TEF thyrotrophic embryonic factor -1.49153
IGF2R insulin-like growth factor 2 receptor -1.48724
SRP9 signal recognition particle 9kDa -1.48459
FAM101B family with sequence similarity 101, member B -1.46865
TEK TEK tyrosine kinase, endothelial -1.45766
TMEM160 transmembrane protein 160 -1.45548
EIF4A2 eukaryotic translation initiation factor 4A2 -1.44134
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 -1.42755
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -1.42305
UBA7 ubiquitin-like modifier activating enzyme 7 -1.40994
CDH22 cadherin 22, type 2 -1.40795
UROD uroporphyrinogen decarboxylase -1.40712
ADIPOR2 adiponectin receptor 2 -1.38489
GPX2 glutathione peroxidase 2 -1.3831
ADCY2 adenylate cyclase 2 (brain) -1.37773
TMEM141 transmembrane protein 141 -1.37614
ITPKB inositol-trisphosphate 3-kinase B -1.37529
HPS4 Hermansky-Pudlak syndrome 4 -1.37166
DDAH2 dimethylarginine dimethylaminohydrolase 2 -1.37054
SKI SKI proto-oncogene -1.35984
SAP18 Sin3A-associated protein, 18kDa -1.35899
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -1.35856
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -1.35789
ANAPC11 anaphase promoting complex subunit 11 -1.3554
C5ORF51 chromosome 5 open reading frame 51 -1.35112
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) -1.34385
WNT2B wingless-type MMTV integration site family, member 2B -1.34314
GHR growth hormone receptor -1.34017
MRPL38 mitochondrial ribosomal protein L38 -1.33994
CPNE3 copine III -1.33601
HOMER2 homer scaffolding protein 2 -1.33532
LOXL1 lysyl oxidase-like 1 -1.33411
PC pyruvate carboxylase -1.33405
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) -1.32875
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -1.32409
GABARAPL1 GABA(A) receptor-associated protein like 1 -1.32407
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 -1.32144
ZMYND11 zinc finger, MYND-type containing 11 -1.32036
SERINC3 serine incorporator 3 -1.31614
NPEPL1 aminopeptidase-like 1 -1.31142
TCF15 transcription factor 15 (basic helix-loop-helix) -1.31038
GSTM1 glutathione S-transferase mu 1 -1.30927
EMCN endomucin -1.30861
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -1.30797
TCF4 transcription factor 4 -1.30519
IFNAR1 interferon (alpha, beta and omega) receptor 1 -1.30512
AGRN agrin -1.30216
PMP22 peripheral myelin protein 22 -1.30212
SESN1 sestrin 1 -1.30012
TGFB2 transforming growth factor, beta 2 -1.29825
WDR7 WD repeat domain 7 -1.29811
CNPY2 canopy FGF signaling regulator 2 -1.29639
TMEM168 transmembrane protein 168 -1.29457
JTB jumping translocation breakpoint -1.29331
EPC1 enhancer of polycomb homolog 1 (Drosophila) -1.29288
TTC33 tetratricopeptide repeat domain 33 -1.28963
KLF9 Kruppel-like factor 9 -1.28776
IL27RA interleukin 27 receptor, alpha -1.28734
UBTF upstream binding transcription factor, RNA polymerase I -1.28556
CKM creatine kinase, muscle -1.28378
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -1.28172
TEX261 testis expressed 261 -1.28043
PLK3 polo-like kinase 3 -1.27908
ERF Ets2 repressor factor -1.27598
NFS1 NFS1 cysteine desulfurase -1.27591
MKRN2 makorin ring finger protein 2 -1.27534
STRN4 striatin, calmodulin binding protein 4 -1.27381
FAM134A family with sequence similarity 134, member A -1.27095
GPX3 glutathione peroxidase 3 -1.27085
MECR mitochondrial trans-2-enoyl-CoA reductase -1.26911
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -1.26867
GOLGA4 golgin A4 -1.2655
HAGH hydroxyacylglutathione hydrolase -1.26008
FBXW2 F-box and WD repeat domain containing 2 -1.25121
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.25037
ADK adenosine kinase -1.24823
SYK spleen tyrosine kinase -1.24732
TMOD3 tropomodulin 3 (ubiquitous) -1.24709
ITFG1 integrin alpha FG-GAP repeat containing 1 -1.24528
SAR1A secretion associated, Ras related GTPase 1A -1.24347
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -1.24323
CP ceruloplasmin (ferroxidase) -1.23773
GALR2 galanin receptor 2 -1.23289
DPF2 D4, zinc and double PHD fingers family 2 -1.2308
YES1 YES proto-oncogene 1, Src family tyrosine kinase -1.23033
MPDZ multiple PDZ domain protein -1.22847
FDX1 ferredoxin 1 -1.22577
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -1.22387
SDPR serum deprivation response -1.2223
GALK2 galactokinase 2 -1.22104
LAMA5 laminin, alpha 5 -1.21897
PTPRU protein tyrosine phosphatase, receptor type, U -1.21895
PRDX3 peroxiredoxin 3 -1.21805
CD34 CD34 molecule -1.21468
MFGE8 milk fat globule-EGF factor 8 protein -1.21427
LRRC58 leucine rich repeat containing 58 -1.21294
ITM2B integral membrane protein 2B -1.21237
CDADC1 cytidine and dCMP deaminase domain containing 1 -1.21122
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -1.20881
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -1.20625
TSFM Ts translation elongation factor, mitochondrial -1.20523
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled -1.20322
CSAD cysteine sulfinic acid decarboxylase -1.20218
ROGDI rogdi homolog (Drosophila) -1.20025
IMMT inner membrane protein, mitochondrial -1.19995
ATG12 autophagy related 12 -1.19886
GKAP1 G kinase anchoring protein 1 -1.1966
ATP9A ATPase, class II, type 9A -1.19581
TSEN15 TSEN15 tRNA splicing endonuclease subunit -1.19557
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -1.19528
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -1.19461
ZBTB17 zinc finger and BTB domain containing 17 -1.19293
RPL37A ribosomal protein L37a -1.19252
SPRYD7 SPRY domain containing 7 -1.19079
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -1.19048
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 -1.18924
MFAP5 microfibrillar associated protein 5 -1.18885
SMC6 structural maintenance of chromosomes 6 -1.18593
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -1.18456
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -1.18265
VAMP5 vesicle-associated membrane protein 5 -1.18111
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -1.17957
UBTD2 ubiquitin domain containing 2 -1.17869
FAM103A1 family with sequence similarity 103, member A1 -1.17803
UBL5 ubiquitin-like 5 -1.17676
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -1.17644
DYNLRB1 dynein, light chain, roadblock-type 1 -1.17585
KIAA0100 KIAA0100 -1.17299
HIST1H2BJ histone cluster 1, H2bj -1.17266
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -1.16865
TMEM123 transmembrane protein 123 -1.16841
GCK glucokinase (hexokinase 4) -1.16795
ANK1 ankyrin 1, erythrocytic -1.16496
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -1.16285
NR1D1 nuclear receptor subfamily 1, group D, member 1 -1.16219
MYH4 myosin, heavy chain 4, skeletal muscle -1.15717
ROMO1 reactive oxygen species modulator 1 -1.15443
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -1.14903
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 -1.14712
STRA6 stimulated by retinoic acid 6 -1.14236
ZNF23 zinc finger protein 23 -1.14054
PDE8A phosphodiesterase 8A -1.13984
SELV selenoprotein V -1.13976
RSPH1 radial spoke head 1 homolog (Chlamydomonas) -1.13953
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -1.13925
ZNF322 zinc finger protein 322 -1.13774
MAU2 MAU2 sister chromatid cohesion factor -1.13379
GOLIM4 golgi integral membrane protein 4 -1.13358
RNF10 ring finger protein 10 -1.13332
SMAD1 SMAD family member 1 -1.1328
MYBPC3 myosin binding protein C, cardiac -1.13262
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -1.13176
LBP lipopolysaccharide binding protein -1.1313
HINT2 histidine triad nucleotide binding protein 2 -1.13129
ARTN artemin -1.1286
CDK11A cyclin-dependent kinase 11A -1.1259
IVD isovaleryl-CoA dehydrogenase -1.12513
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -1.12505
ARPC5L actin related protein 2/3 complex, subunit 5-like -1.12421
ZHX1 zinc fingers and homeoboxes 1 -1.12417
MEF2A myocyte enhancer factor 2A -1.12335
SYNGR1 synaptogyrin 1 -1.12054
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -1.12001
OSBPL5 oxysterol binding protein-like 5 -1.11853
WWTR1 WW domain containing transcription regulator 1 -1.11732
BGN biglycan -1.11705
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -1.11204
MYO5B myosin VB -1.11104
DPP8 dipeptidyl-peptidase 8 -1.11012
BAG1 BCL2-associated athanogene -1.10942
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -1.10906
PRRT4 proline-rich transmembrane protein 4 -1.10727