Triamcinolone_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Triamcinolone perturbation in COLO 205 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Triamcinolone_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.246312
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.110344
EGR1 early growth response 1 0.100135
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0895309
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.088103
SHB Src homology 2 domain containing adaptor protein B 0.0830473
MYH9 myosin, heavy chain 9, non-muscle 0.0806377
AKAP13 A kinase (PRKA) anchor protein 13 0.0769866
MYO1E myosin IE 0.0719819
SIPA1L2 signal-induced proliferation-associated 1 like 2 0.0695842
EZR ezrin 0.0693485
MLPH melanophilin 0.068001
EFNB2 ephrin-B2 0.0634995
FAT1 FAT atypical cadherin 1 0.0623721
GCLC glutamate-cysteine ligase, catalytic subunit 0.0613813
SEPTIN9 septin 9 0.0610676
ANXA2 annexin A2 0.0598534
SMAD3 SMAD family member 3 0.0565734
LPP LIM domain containing preferred translocation partner in lipoma 0.055554
VEGFA vascular endothelial growth factor A 0.0531198
AREG amphiregulin 0.0522599
EXT1 exostosin glycosyltransferase 1 0.0495534
RNF213 ring finger protein 213 0.0476024
STK24 serine/threonine kinase 24 0.0470515
ATP11A ATPase, class VI, type 11A 0.0468656
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0462231
ITGA6 integrin, alpha 6 0.0459595
EEF2 eukaryotic translation elongation factor 2 0.0429364
TJP1 tight junction protein 1 0.0420402
EPHB2 EPH receptor B2 0.042031
BCL2L1 BCL2-like 1 0.0420222
DUSP10 dual specificity phosphatase 10 0.0416767
IGF1R insulin-like growth factor 1 receptor 0.040547
DIAPH1 diaphanous-related formin 1 0.0396859
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0396375
JUN jun proto-oncogene 0.0390373
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0387655
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0383265
PADI1 peptidyl arginine deiminase, type I 0.0383106
MYO5B myosin VB 0.0381755
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0379144
DSPP dentin sialophosphoprotein 0.0375367
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0366297
EPHA2 EPH receptor A2 0.0362718
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0359611
APP amyloid beta (A4) precursor protein 0.0353857
SH3PXD2A SH3 and PX domains 2A 0.0350313
PRSS22 protease, serine, 22 0.0349514
STS steroid sulfatase (microsomal), isozyme S 0.0344014
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0342851
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0342242
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0341183
CDHR2 cadherin-related family member 2 0.0340038
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0338963
MPRIP myosin phosphatase Rho interacting protein 0.0334912
C6ORF132 chromosome 6 open reading frame 132 0.0325712
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.032554
MACF1 microtubule-actin crosslinking factor 1 0.0325054
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0322418
FHIT fragile histidine triad 0.0317445
KIF16B kinesin family member 16B 0.0315223
TPM3 tropomyosin 3 0.0313475
BAIAP2L1 BAI1-associated protein 2-like 1 0.0309731
MX2 MX dynamin-like GTPase 2 0.0307497
SRRM2 serine/arginine repetitive matrix 2 0.0303922
TRERF1 transcriptional regulating factor 1 0.029451
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0292729
KRT18 keratin 18, type I 0.029261
MCL1 myeloid cell leukemia 1 0.0287625
PLSCR1 phospholipid scramblase 1 0.0287296
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0281823
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0281169
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0280481
ERN1 endoplasmic reticulum to nucleus signaling 1 0.0280014
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0272299
PDZD8 PDZ domain containing 8 0.0272109
MYH14 myosin, heavy chain 14, non-muscle 0.0271471
DUSP16 dual specificity phosphatase 16 0.0267297
DOCK1 dedicator of cytokinesis 1 0.0265084
PHF3 PHD finger protein 3 0.0264647
FEM1C fem-1 homolog c (C. elegans) 0.0260704
USP9X ubiquitin specific peptidase 9, X-linked 0.0260126
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0256868
TMC5 transmembrane channel-like 5 0.0254871
BTBD9 BTB (POZ) domain containing 9 0.0253767
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0252385
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.0252283
NIBAN2 niban apoptosis regulator 2 0.0252018
MACC1 metastasis associated in colon cancer 1 0.0251
TSC22D1 TSC22 domain family, member 1 0.0248809
RIGI RNA sensor RIG-I 0.0247425
WNK1 WNK lysine deficient protein kinase 1 0.024597
ETV6 ets variant 6 0.0239242
MX1 MX dynamin-like GTPase 1 0.0235767
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0234971
ARGLU1 arginine and glutamate rich 1 0.0234506
NCOR2 nuclear receptor corepressor 2 0.0234219
RBM47 RNA binding motif protein 47 0.0232132
DST dystonin 0.0231743
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0231613

decreased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0995185
TPT1 tumor protein, translationally-controlled 1 -0.0835549
RHOBTB3 Rho-related BTB domain containing 3 -0.0792764
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0789812
PTMA prothymosin, alpha -0.0711778
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0673014
LYZ lysozyme -0.0595211
TXNIP thioredoxin interacting protein -0.0566285
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0551682
UBC ubiquitin C -0.0509362
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0501467
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0495954
ZMYND8 zinc finger, MYND-type containing 8 -0.0420269
FNDC3A fibronectin type III domain containing 3A -0.0416638
PERP PERP, TP53 apoptosis effector -0.0410516
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0364467
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0362345
FTL ferritin, light polypeptide -0.0350038
B2M beta-2-microglobulin -0.0341128
RPS6 ribosomal protein S6 -0.0340402
DSTN destrin (actin depolymerizing factor) -0.0337445
PDIA3 protein disulfide isomerase family A, member 3 -0.0313066
CTSD cathepsin D -0.0311278
RPL34 ribosomal protein L34 -0.0310355
RPS24 ribosomal protein S24 -0.0310236
RPL35A ribosomal protein L35a -0.0308576
GNAS GNAS complex locus -0.0305647
GCC2 GRIP and coiled-coil domain containing 2 -0.030369
FNIP1 folliculin interacting protein 1 -0.0303688
XAF1 XIAP associated factor 1 -0.0301484
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0299405
DIAPH3 diaphanous-related formin 3 -0.0296522
HLA-A major histocompatibility complex, class I, A -0.0296297
S100A6 S100 calcium binding protein A6 -0.0290042
VDAC1 voltage-dependent anion channel 1 -0.0288096
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0285044
TOP2A topoisomerase (DNA) II alpha 170kDa -0.027873
IFI27 interferon, alpha-inducible protein 27 -0.0276221
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0273177
STAT1 signal transducer and activator of transcription 1, 91kDa -0.02726
NCKAP5 NCK-associated protein 5 -0.0271805
SMC4 structural maintenance of chromosomes 4 -0.0269831
WASF2 WAS protein family, member 2 -0.0268199
CD46 CD46 molecule, complement regulatory protein -0.0267834
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.0263319
UBE2B ubiquitin-conjugating enzyme E2B -0.026198
RUNX1 runt-related transcription factor 1 -0.0261375
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0260243
NUCB2 nucleobindin 2 -0.0259163
HLA-E major histocompatibility complex, class I, E -0.0258256
LY6E lymphocyte antigen 6 complex, locus E -0.0257921
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0253413
RPLP1 ribosomal protein, large, P1 -0.0252224
ANKHD1 ankyrin repeat and KH domain containing 1 -0.025013
ZBTB20 zinc finger and BTB domain containing 20 -0.0249608
EIF1 eukaryotic translation initiation factor 1 -0.0248774
SP100 SP100 nuclear antigen -0.0248022
ZNF609 zinc finger protein 609 -0.0244244
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0241464
CSTB cystatin B (stefin B) -0.0240656
HLA-B major histocompatibility complex, class I, B -0.0235498
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0234059
IFI6 interferon, alpha-inducible protein 6 -0.0232568
PIAS1 protein inhibitor of activated STAT, 1 -0.0231977
ARID4B AT rich interactive domain 4B (RBP1-like) -0.023113
RPL12 ribosomal protein L12 -0.0230341
MPHOSPH8 M-phase phosphoprotein 8 -0.0226558
PTEN phosphatase and tensin homolog -0.0226301
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.0225929
HLA-C major histocompatibility complex, class I, C -0.0225744
ABLIM1 actin binding LIM protein 1 -0.0223603
RAB2A RAB2A, member RAS oncogene family -0.0215566
CENPF centromere protein F, 350/400kDa -0.0215283
AGR2 anterior gradient 2 -0.0213511
EPCAM epithelial cell adhesion molecule -0.0213163
EHF ets homologous factor -0.0212635
TMSB10 thymosin beta 10 -0.0212555
TMEM165 transmembrane protein 165 -0.0207009
NPSR1 neuropeptide S receptor 1 -0.0206312
NRIP1 nuclear receptor interacting protein 1 -0.0206123
TSC22D2 TSC22 domain family, member 2 -0.0200172
RBM25 RNA binding motif protein 25 -0.0200065
EPB41 erythrocyte membrane protein band 4.1 -0.0199131
TMEM263 transmembrane protein 263 -0.0196196
HMGB1 high mobility group box 1 -0.0195254
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0195217
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.0194092
RNF149 ring finger protein 149 -0.0193322
H1-0 H1.0 linker histone -0.0193227
MTDH metadherin -0.0191925
H3-3B H3.3 histone B -0.0191787
STAU1 staufen double-stranded RNA binding protein 1 -0.0191612
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.018959
TSHZ2 teashirt zinc finger homeobox 2 -0.0189134
RPS23 ribosomal protein S23 -0.0188924
PRRC1 proline-rich coiled-coil 1 -0.0188811
RTN3 reticulon 3 -0.0186043
ARHGAP12 Rho GTPase activating protein 12 -0.0182967
CD164 CD164 molecule, sialomucin -0.0182589
ZMYM2 zinc finger, MYM-type 2 -0.0182371