| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triamcinolone perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triamcinolone_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.238674 |
| MT2A | metallothionein 2A | 0.131509 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0846678 |
| VEGFA | vascular endothelial growth factor A | 0.0778778 |
| PLEC | plectin | 0.0647948 |
| MT1X | metallothionein 1X | 0.0571479 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0544568 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0403463 |
| FLNA | filamin A, alpha | 0.0380746 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0377411 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0346659 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.032209 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0302024 |
| PRELID2 | PRELI domain containing 2 | 0.0298003 |
| RPL37A | ribosomal protein L37a | 0.0287151 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.028332 |
| ANGPTL4 | angiopoietin-like 4 | 0.0263639 |
| NAV2 | neuron navigator 2 | 0.026164 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0261296 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0261153 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.025325 |
| EGR1 | early growth response 1 | 0.0243413 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0228073 |
| TOP1 | topoisomerase (DNA) I | 0.0224145 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0216141 |
| HDAC9 | histone deacetylase 9 | 0.0206103 |
| MYO1B | myosin IB | 0.0205784 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0205627 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0201689 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0197856 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.019626 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0196235 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.01917 |
| APP | amyloid beta (A4) precursor protein | 0.0190151 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.01895 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0189408 |
| SEPTIN9 | septin 9 | 0.0188782 |
| RPL11 | ribosomal protein L11 | 0.018522 |
| PRRC2C | proline-rich coiled-coil 2C | 0.018338 |
| RPS3 | ribosomal protein S3 | 0.0183058 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0181132 |
| RPL26 | ribosomal protein L26 | 0.0180736 |
| INTS6 | integrator complex subunit 6 | 0.0180323 |
| YAP1 | Yes-associated protein 1 | 0.0180002 |
| RACK1 | receptor for activated C kinase 1 | 0.0178847 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0174421 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0170617 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.016945 |
| IL6ST | interleukin 6 signal transducer | 0.0164731 |
| RCC1 | regulator of chromosome condensation 1 | 0.0164076 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0163193 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0162997 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0162871 |
| ANKRD28 | ankyrin repeat domain 28 | 0.016272 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0158313 |
| KLC1 | kinesin light chain 1 | 0.0155832 |
| EFNA5 | ephrin-A5 | 0.0155576 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0154342 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0152475 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0147901 |
| CDK19 | cyclin-dependent kinase 19 | 0.0147788 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0147444 |
| GLRX | glutaredoxin (thioltransferase) | 0.0146289 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0144544 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0142123 |
| RPS8 | ribosomal protein S8 | 0.0140812 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0139681 |
| RPS12 | ribosomal protein S12 | 0.0139224 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0138706 |
| SON | SON DNA binding protein | 0.0138509 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.013814 |
| STC2 | stanniocalcin 2 | 0.0137668 |
| RPL9 | ribosomal protein L9 | 0.0137038 |
| GOLGA3 | golgin A3 | 0.0136504 |
| NHSL1 | NHS-like 1 | 0.013519 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0135113 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0134964 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0133723 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0132319 |
| GLCCI1 | glucocorticoid induced 1 | 0.0132242 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0132144 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0131742 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0131449 |
| SVIL | supervillin | 0.0131152 |
| RPL23 | ribosomal protein L23 | 0.0130989 |
| DCLK1 | doublecortin-like kinase 1 | 0.0130109 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0129345 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0129261 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0128492 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0128041 |
| RPS10 | ribosomal protein S10 | 0.0127705 |
| BRD4 | bromodomain containing 4 | 0.0126162 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0125822 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.012578 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0125187 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0125123 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0125099 |
| NEK10 | NIMA-related kinase 10 | 0.0124011 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0123923 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0123643 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.441206 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.228706 |
| FN1 | fibronectin 1 | -0.205614 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.151469 |
| VIM | vimentin | -0.148645 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.134177 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122888 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0963241 |
| CD44 | CD44 molecule (Indian blood group) | -0.0921286 |
| FBN1 | fibrillin 1 | -0.0908449 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0848106 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.084476 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0777017 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0694028 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0690336 |
| TPM4 | tropomyosin 4 | -0.0674334 |
| VCAN | versican | -0.066575 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0645514 |
| IER3 | immediate early response 3 | -0.0617191 |
| COL1A1 | collagen, type I, alpha 1 | -0.0581879 |
| ATP13A3 | ATPase type 13A3 | -0.0577732 |
| PDE10A | phosphodiesterase 10A | -0.0569853 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0558291 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0537419 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0505193 |
| ENO1 | enolase 1, (alpha) | -0.0477255 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0472807 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0447224 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0444888 |
| MAP1B | microtubule-associated protein 1B | -0.0443307 |
| CANX | calnexin | -0.042727 |
| COL1A2 | collagen, type I, alpha 2 | -0.0421534 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0419464 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0413873 |
| CADM1 | cell adhesion molecule 1 | -0.0406033 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.040096 |
| MAP4 | microtubule-associated protein 4 | -0.0395207 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0386384 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0385762 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0382511 |
| GOLGA4 | golgin A4 | -0.0364584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0357621 |
| GLIS3 | GLIS family zinc finger 3 | -0.0353025 |
| MTSS1 | metastasis suppressor 1 | -0.0351381 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0344434 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0330654 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0330631 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0322457 |
| EGFR | epidermal growth factor receptor | -0.0322447 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0321426 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0320181 |
| BNC2 | basonuclin 2 | -0.0319006 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0318124 |
| DSTN | destrin (actin depolymerizing factor) | -0.0315124 |
| PGK1 | phosphoglycerate kinase 1 | -0.0310308 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0302733 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0302027 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.029562 |
| NDRG1 | N-myc downstream regulated 1 | -0.0294275 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0287336 |
| INHBA | inhibin, beta A | -0.0281592 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0277258 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0276687 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0274218 |
| AHNAK | AHNAK nucleoprotein | -0.0268596 |
| STC1 | stanniocalcin 1 | -0.0265548 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0263594 |
| ZNF292 | zinc finger protein 292 | -0.0261564 |
| CALD1 | caldesmon 1 | -0.0261131 |
| CDH13 | cadherin 13 | -0.0258524 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0257037 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0256133 |
| FTL | ferritin, light polypeptide | -0.0255318 |
| TRAM1 | translocation associated membrane protein 1 | -0.0253722 |
| LOXL2 | lysyl oxidase-like 2 | -0.0253387 |
| RRBP1 | ribosome binding protein 1 | -0.0252805 |
| SQLE | squalene epoxidase | -0.0251454 |
| CALU | calumenin | -0.0248892 |
| SETD5 | SET domain containing 5 | -0.0248476 |
| ANXA2 | annexin A2 | -0.0248242 |
| SMYD3 | SET and MYND domain containing 3 | -0.0243848 |
| SBF2 | SET binding factor 2 | -0.0241097 |
| NAV1 | neuron navigator 1 | -0.0240652 |
| EPHB1 | EPH receptor B1 | -0.0236668 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0232014 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0231201 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0228144 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0222684 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0222512 |
| USP3 | ubiquitin specific peptidase 3 | -0.0222287 |
| ARRDC3 | arrestin domain containing 3 | -0.0222192 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0218679 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0217174 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0216906 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.021516 |
| PALLD | palladin, cytoskeletal associated protein | -0.0213855 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0210773 |
| SEPTIN7 | septin 7 | -0.0208394 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0207681 |
| TMEM263 | transmembrane protein 263 | -0.0205508 |
