Triamcinolone_HepG2/C3A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Triamcinolone perturbation in HepG2/C3A cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Triamcinolone_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
IGF2 insulin-like growth factor 2 0.190824
APOB apolipoprotein B 0.144008
ERRFI1 ERBB receptor feedback inhibitor 1 0.108385
FN1 fibronectin 1 0.0999397
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0933208
DSPP dentin sialophosphoprotein 0.0901035
VEGFA vascular endothelial growth factor A 0.0821807
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0804338
IGFBP1 insulin-like growth factor binding protein 1 0.0672347
MYH9 myosin, heavy chain 9, non-muscle 0.0642001
EEF2 eukaryotic translation elongation factor 2 0.0616951
MACF1 microtubule-actin crosslinking factor 1 0.0548396
EPAS1 endothelial PAS domain protein 1 0.0540226
BHLHE40 basic helix-loop-helix family, member e40 0.0538478
ELL2 elongation factor, RNA polymerase II, 2 0.0529517
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0506967
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0489085
PLEC plectin 0.0484185
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0473619
TNS1 tensin 1 0.0462434
SMAD3 SMAD family member 3 0.0417515
AFDN afadin, adherens junction formation factor 0.0416989
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0413246
A2M alpha-2-macroglobulin 0.0386147
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0374092
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0362712
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0354984
C3 complement component 3 0.0353974
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.0345266
DDIT4 DNA-damage-inducible transcript 4 0.0326585
KDM3A lysine (K)-specific demethylase 3A 0.0313215
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0308952
SOD2 superoxide dismutase 2, mitochondrial 0.0294801
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0287786
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.0283545
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0279907
DOCK5 dedicator of cytokinesis 5 0.0277434
RBM39 RNA binding motif protein 39 0.0270548
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.0269871
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.0268101
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0263351
RPL3 ribosomal protein L3 0.0257632
EIF4B eukaryotic translation initiation factor 4B 0.0254618
CFB complement factor B 0.0251625
FAM13A family with sequence similarity 13, member A 0.0250949
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0250149
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0243357
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0240529
IQSEC1 IQ motif and Sec7 domain 1 0.023829
ARHGAP9 Rho GTPase activating protein 9 0.0236112
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0235501
JUN jun proto-oncogene 0.0234688
NAMPT nicotinamide phosphoribosyltransferase 0.0231712
CAMTA1 calmodulin binding transcription activator 1 0.0230197
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0225302
KCMF1 potassium channel modulatory factor 1 0.022314
DNAH5 dynein, axonemal, heavy chain 5 0.0221283
NFE2L1 nuclear factor, erythroid 2-like 1 0.0214743
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0214417
CEP250 centrosomal protein 250kDa 0.0213595
RAD21 RAD21 homolog (S. pombe) 0.0213402
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0212606
FAT1 FAT atypical cadherin 1 0.021061
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.0209301
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0207412
JAK1 Janus kinase 1 0.0207235
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0206062
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.020587
SOS1 son of sevenless homolog 1 (Drosophila) 0.0201905
RRBP1 ribosome binding protein 1 0.0200761
TNIP1 TNFAIP3 interacting protein 1 0.0198609
SPAG9 sperm associated antigen 9 0.0198326
HLF hepatic leukemia factor 0.0197058
CCNY cyclin Y 0.0194824
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.019247
HSPA12A heat shock 70kDa protein 12A 0.0190978
HOOK2 hook microtubule-tethering protein 2 0.0190951
SVIL supervillin 0.018713
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.018492
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.0184868
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.0184352
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0184165
DSCAM Down syndrome cell adhesion molecule 0.0184149
PDZD8 PDZ domain containing 8 0.0183136
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0182278
SYNE1 spectrin repeat containing, nuclear envelope 1 0.0181753
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.0181744
SHB Src homology 2 domain containing adaptor protein B 0.0181615
RPL38 ribosomal protein L38 0.0177132
NONO non-POU domain containing, octamer-binding 0.0175305
MTUS1 microtubule associated tumor suppressor 1 0.0174262
APP amyloid beta (A4) precursor protein 0.0173921
MATR3 matrin 3 0.0172489
PER2 period circadian clock 2 0.0170381
HSPA8 heat shock 70kDa protein 8 0.0169758
NKD1 naked cuticle homolog 1 (Drosophila) 0.0169715
TF transferrin 0.0166611
WAPL WAPL cohesin release factor 0.0164247
SRRM2 serine/arginine repetitive matrix 2 0.0162999
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.0161912

decreased expression

Symbol Name Standardized Value
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.225781
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.193325
AKAP12 A kinase (PRKA) anchor protein 12 -0.133622
APOA2 apolipoprotein A-II -0.132938
HMGA1 high mobility group AT-hook 1 -0.120252
MT2A metallothionein 2A -0.115251
TMSB10 thymosin beta 10 -0.11348
TPT1 tumor protein, translationally-controlled 1 -0.0940004
PLIN2 perilipin 2 -0.0856834
FRMD5 FERM domain containing 5 -0.0835241
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0831023
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0799717
RPS6 ribosomal protein S6 -0.078597
ENO1 enolase 1, (alpha) -0.0773472
ZBTB20 zinc finger and BTB domain containing 20 -0.0739059
AHSG alpha-2-HS-glycoprotein -0.0728911
MAML2 mastermind-like 2 (Drosophila) -0.0724708
GMDS GDP-mannose 4,6-dehydratase -0.0679844
VCL vinculin -0.065955
EHBP1 EH domain binding protein 1 -0.0645133
RPS24 ribosomal protein S24 -0.0640069
ASPH aspartate beta-hydroxylase -0.0622542
TIMP1 TIMP metallopeptidase inhibitor 1 -0.059976
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0542517
ITGAV integrin, alpha V -0.0537216
FTL ferritin, light polypeptide -0.0518215
SLC38A2 solute carrier family 38, member 2 -0.0515713
DST dystonin -0.0484728
PTCHD4 patched domain containing 4 -0.0479503
RPL23 ribosomal protein L23 -0.0475509
RPL35A ribosomal protein L35a -0.0467816
RPS19 ribosomal protein S19 -0.046729
RPL37A ribosomal protein L37a -0.0461247
SOX5 SRY (sex determining region Y)-box 5 -0.0447685
TMEM123 transmembrane protein 123 -0.0430269
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.0413466
PARD3 par-3 family cell polarity regulator -0.0409481
NPAS2 neuronal PAS domain protein 2 -0.0407665
RPS21 ribosomal protein S21 -0.0405514
TM4SF1 transmembrane 4 L six family member 1 -0.0401779
RPL11 ribosomal protein L11 -0.0399475
RPL31 ribosomal protein L31 -0.0397006
PDLIM5 PDZ and LIM domain 5 -0.0396394
TPM4 tropomyosin 4 -0.0390723
PERP PERP, TP53 apoptosis effector -0.0390431
RPS8 ribosomal protein S8 -0.03819
RPL34 ribosomal protein L34 -0.0378464
ISG15 ISG15 ubiquitin-like modifier -0.0376281
POTEF POTE ankyrin domain family, member F -0.0364901
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0358662
LYZ lysozyme -0.0351881
RPS14 ribosomal protein S14 -0.0349216
RPLP2 ribosomal protein, large, P2 -0.0346488
ATXN1 ataxin 1 -0.0344626
IFITM1 interferon induced transmembrane protein 1 -0.0339302
GNAS GNAS complex locus -0.0332675
RPL9 ribosomal protein L9 -0.033184
S100A9 S100 calcium binding protein A9 -0.0323823
MAP1B microtubule-associated protein 1B -0.0320376
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0318215
IFI6 interferon, alpha-inducible protein 6 -0.0317099
RPL28 ribosomal protein L28 -0.031666
AMBP alpha-1-microglobulin/bikunin precursor -0.0312336
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0309484
UBC ubiquitin C -0.030833
CNKSR3 CNKSR family member 3 -0.0307215
RPS12 ribosomal protein S12 -0.0305136
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0305064
HLA-A major histocompatibility complex, class I, A -0.0303496
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0298712
PRKCA protein kinase C, alpha -0.0291479
RPS5 ribosomal protein S5 -0.0281287
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0277243
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0276418
RPL12 ribosomal protein L12 -0.0274445
DLC1 DLC1 Rho GTPase activating protein -0.0274355
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0273403
PFN1 profilin 1 -0.0270024
FMNL2 formin-like 2 -0.0267738
GK glycerol kinase -0.0266754
RPS23 ribosomal protein S23 -0.0265978
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0265517
RPS29 ribosomal protein S29 -0.0264136
ACTG1 actin gamma 1 -0.0262516
RPS27A ribosomal protein S27a -0.0260516
PTMA prothymosin, alpha -0.0258738
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0257239
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0256874
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0256784
PKM pyruvate kinase, muscle -0.0256085
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0254259
DTNA dystrobrevin, alpha -0.0253766
RPLP1 ribosomal protein, large, P1 -0.0253024
TRAM1 translocation associated membrane protein 1 -0.0252246
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.0252118
RPL27 ribosomal protein L27 -0.0248725
SOX4 SRY (sex determining region Y)-box 4 -0.0246948
RPS3 ribosomal protein S3 -0.0246268
GPC3 glypican 3 -0.0245811
NHSL1 NHS-like 1 -0.0241009