| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triamcinolone perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triamcinolone_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | 0.0890041 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0888803 |
| MT2A | metallothionein 2A | 0.0843663 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0832488 |
| GRAMD1B | GRAM domain containing 1B | 0.0733898 |
| INTS6 | integrator complex subunit 6 | 0.0719162 |
| EGFR | epidermal growth factor receptor | 0.0618668 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.057273 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0526158 |
| IRS2 | insulin receptor substrate 2 | 0.0505998 |
| LMO7 | LIM domain 7 | 0.0479399 |
| S100P | S100 calcium binding protein P | 0.0474769 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0456313 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0448464 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0408725 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0400697 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0367304 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0348275 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.034822 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0346163 |
| FUS | FUS RNA binding protein | 0.033933 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0335138 |
| MCL1 | myeloid cell leukemia 1 | 0.0333064 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0321926 |
| HOMER1 | homer scaffolding protein 1 | 0.0311329 |
| RPS3 | ribosomal protein S3 | 0.0309406 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0300322 |
| AREG | amphiregulin | 0.0298163 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0296519 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0294886 |
| DNER | delta/notch-like EGF repeat containing | 0.0293125 |
| ATF6 | activating transcription factor 6 | 0.0292154 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0285099 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0282654 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0276026 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0272382 |
| RPS17 | ribosomal protein S17 | 0.0264923 |
| RPL37A | ribosomal protein L37a | 0.0263075 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0260337 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.02496 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0247302 |
| HDAC4 | histone deacetylase 4 | 0.0245011 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0240622 |
| RNF213 | ring finger protein 213 | 0.0240584 |
| DSPP | dentin sialophosphoprotein | 0.0239445 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0234329 |
| BRD2 | bromodomain containing 2 | 0.02318 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0227484 |
| RPLP0 | ribosomal protein, large, P0 | 0.0223085 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0220913 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0217685 |
| RPS12 | ribosomal protein S12 | 0.0214075 |
| FNDC3A | fibronectin type III domain containing 3A | 0.021189 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0209724 |
| B2M | beta-2-microglobulin | 0.0206301 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0204097 |
| WWOX | WW domain containing oxidoreductase | 0.0203971 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0203135 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0202139 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0201236 |
| CST3 | cystatin C | 0.0201126 |
| CTBP2 | C-terminal binding protein 2 | 0.0200509 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0200341 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0199862 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0198655 |
| HYOU1 | hypoxia up-regulated 1 | 0.0198555 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0198431 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0197364 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0196336 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0195971 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0194958 |
| VEGFA | vascular endothelial growth factor A | 0.0194509 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0193847 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0193149 |
| MT1X | metallothionein 1X | 0.0190824 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0190304 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.018939 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0188042 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.018772 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0187614 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0185412 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0185103 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0184956 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0184632 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0184502 |
| BMP6 | bone morphogenetic protein 6 | 0.0184016 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.01821 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0181388 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0180265 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0179132 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0176381 |
| WDR1 | WD repeat domain 1 | 0.0176217 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0175032 |
| GALK2 | galactokinase 2 | 0.0173856 |
| RUNX1 | runt-related transcription factor 1 | 0.0173125 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0172875 |
| RAB7A | RAB7A, member RAS oncogene family | 0.017205 |
| HMGA2 | high mobility group AT-hook 2 | 0.0171897 |
| SVIL | supervillin | 0.0171627 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.016989 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.320683 |
| ASPH | aspartate beta-hydroxylase | -0.193881 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0982639 |
| CES1 | carboxylesterase 1 | -0.0595535 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.055913 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0498235 |
| H1-0 | H1.0 linker histone | -0.0493952 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0460511 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0447246 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0435435 |
| TXNRD1 | thioredoxin reductase 1 | -0.0434982 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0427706 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0423061 |
| OSMR | oncostatin M receptor | -0.0418688 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0413332 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0388201 |
| GPC6 | glypican 6 | -0.0382194 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0378647 |
| TPD52 | tumor protein D52 | -0.0374572 |
| ENO1 | enolase 1, (alpha) | -0.0369924 |
| CDCP1 | CUB domain containing protein 1 | -0.0364634 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0358542 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0355189 |
| AHNAK | AHNAK nucleoprotein | -0.034778 |
| MKI67 | marker of proliferation Ki-67 | -0.034706 |
| TMEM165 | transmembrane protein 165 | -0.0344032 |
| NGLY1 | N-glycanase 1 | -0.0334678 |
| PGK1 | phosphoglycerate kinase 1 | -0.0330361 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0321891 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0320421 |
| FAM13A | family with sequence similarity 13, member A | -0.0315875 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0311865 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0305948 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0300884 |
| RASA2 | RAS p21 protein activator 2 | -0.0296965 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0281135 |
| ACTG1 | actin gamma 1 | -0.0280762 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0278898 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0275904 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0275797 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0274989 |
| CD163L1 | CD163 molecule-like 1 | -0.0273647 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0273218 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.027291 |
| NF1 | neurofibromin 1 | -0.0272737 |
| JMJD1C | jumonji domain containing 1C | -0.0268114 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0260576 |
| RIN2 | Ras and Rab interactor 2 | -0.0260427 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0256126 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0256122 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.025593 |
| ANO6 | anoctamin 6 | -0.0255461 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0254387 |
| SPAG9 | sperm associated antigen 9 | -0.0253561 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0253109 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0248971 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0246163 |
| HDLBP | high density lipoprotein binding protein | -0.0243684 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0233682 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0231427 |
| TLK1 | tousled-like kinase 1 | -0.0227148 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0226183 |
| ARRDC3 | arrestin domain containing 3 | -0.0225829 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0223802 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0220963 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0219894 |
| NDRG1 | N-myc downstream regulated 1 | -0.0217901 |
| SBF2 | SET binding factor 2 | -0.0217202 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0217061 |
| LAMC2 | laminin, gamma 2 | -0.0216343 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.021528 |
| LDHA | lactate dehydrogenase A | -0.0214405 |
| PDE8A | phosphodiesterase 8A | -0.0213271 |
| PARD3 | par-3 family cell polarity regulator | -0.0211772 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0210686 |
| UVRAG | UV radiation resistance associated | -0.0206335 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0204252 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0203919 |
| F11R | F11 receptor | -0.0202807 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0196894 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0196452 |
| ARCN1 | archain 1 | -0.0195844 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.01943 |
| RPL4 | ribosomal protein L4 | -0.0191511 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0189998 |
| HMGA1 | high mobility group AT-hook 1 | -0.0189728 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0189364 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0188945 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0188814 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0188008 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0187038 |
| WASF2 | WAS protein family, member 2 | -0.018614 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.018446 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0184271 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0183843 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.018377 |
| MGAT4C | MGAT4 family, member C | -0.0183739 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0182937 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0182187 |
| DSG2 | desmoglein 2 | -0.0180829 |
