| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triamcinolone perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triamcinolone_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.23325 |
| PM20D1 | peptidase M20 domain containing 1 | 0.202878 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.106109 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.105111 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.101477 |
| NNMT | nicotinamide N-methyltransferase | 0.0783461 |
| MT1X | metallothionein 1X | 0.0687179 |
| PLEC | plectin | 0.0660852 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0557151 |
| UTRN | utrophin | 0.0553173 |
| FGA | fibrinogen alpha chain | 0.0530549 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0505613 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0497999 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0488248 |
| EFNA5 | ephrin-A5 | 0.0488079 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0483829 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0479693 |
| FUS | FUS RNA binding protein | 0.0468422 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0466474 |
| KYNU | kynureninase | 0.0462683 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0456063 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0437508 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0406759 |
| FLNA | filamin A, alpha | 0.0405593 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0404381 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.040064 |
| ANGPTL4 | angiopoietin-like 4 | 0.0392794 |
| AHNAK | AHNAK nucleoprotein | 0.0382473 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0373022 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0368891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0366307 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0346118 |
| SRGN | serglycin | 0.0335576 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0328032 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0324258 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320726 |
| CTBP2 | C-terminal binding protein 2 | 0.0317489 |
| APP | amyloid beta (A4) precursor protein | 0.0313818 |
| PDE10A | phosphodiesterase 10A | 0.0311097 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0302672 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0297376 |
| CUX1 | cut-like homeobox 1 | 0.0291796 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0282265 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0277881 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0277719 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0272796 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0270573 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0268462 |
| COPA | coatomer protein complex, subunit alpha | 0.0265054 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0264207 |
| FAM135A | family with sequence similarity 135, member A | 0.0262627 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0260322 |
| NEBL | nebulette | 0.0258749 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0257594 |
| PRRC2A | proline-rich coiled-coil 2A | 0.025688 |
| POU5F1 | POU class 5 homeobox 1 | 0.0252449 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0249302 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0249145 |
| TOP1 | topoisomerase (DNA) I | 0.0246955 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0245251 |
| PHF20 | PHD finger protein 20 | 0.0244873 |
| USP36 | ubiquitin specific peptidase 36 | 0.0241366 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0238313 |
| NTN4 | netrin 4 | 0.0233891 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0232418 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0231536 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0230428 |
| HDAC4 | histone deacetylase 4 | 0.0223825 |
| ATF6 | activating transcription factor 6 | 0.0220494 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0219793 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0219071 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0217106 |
| CEP250 | centrosomal protein 250kDa | 0.0217078 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0216828 |
| ZFHX3 | zinc finger homeobox 3 | 0.0216483 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0216016 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0213254 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0210696 |
| INTS6 | integrator complex subunit 6 | 0.0210048 |
| RNF213 | ring finger protein 213 | 0.0209987 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0208478 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0208317 |
| EGFR | epidermal growth factor receptor | 0.0207634 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0205347 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0205143 |
| FOXO3 | forkhead box O3 | 0.0204353 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0203363 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0202408 |
| MYO1E | myosin IE | 0.0200277 |
| HLA-B | major histocompatibility complex, class I, B | 0.0199637 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0198792 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0195452 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0194574 |
| CYTH1 | cytohesin 1 | 0.0194437 |
| KLF6 | Kruppel-like factor 6 | 0.0194115 |
| RPL23 | ribosomal protein L23 | 0.0194092 |
| PER1 | period circadian clock 1 | 0.0192925 |
| DCTN1 | dynactin 1 | 0.0189681 |
| MED15 | mediator complex subunit 15 | 0.0188941 |
| FAT1 | FAT atypical cadherin 1 | 0.0188425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.245361 |
| VIM | vimentin | -0.220722 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.199838 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.177655 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.163036 |
| FTL | ferritin, light polypeptide | -0.157929 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.152871 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.124896 |
| TXNRD1 | thioredoxin reductase 1 | -0.116256 |
| POTEF | POTE ankyrin domain family, member F | -0.0988721 |
| IER3 | immediate early response 3 | -0.0833329 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0827992 |
| RTN4 | reticulon 4 | -0.0773197 |
| S100A6 | S100 calcium binding protein A6 | -0.0727834 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0713271 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0606154 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0551236 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0533944 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.053326 |
| PFN1 | profilin 1 | -0.0532741 |
| TMSB10 | thymosin beta 10 | -0.0525181 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0525087 |
| RPS2 | ribosomal protein S2 | -0.051265 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0486831 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0485478 |
| ASPH | aspartate beta-hydroxylase | -0.0484719 |
| RPL19 | ribosomal protein L19 | -0.0473062 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.046207 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0440383 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0429208 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0428526 |
| RPS6 | ribosomal protein S6 | -0.0426546 |
| PTMA | prothymosin, alpha | -0.041821 |
| NAV3 | neuron navigator 3 | -0.0416612 |
| HMGA1 | high mobility group AT-hook 1 | -0.039551 |
| IL6 | interleukin 6 | -0.0391436 |
| STC1 | stanniocalcin 1 | -0.0386209 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0379763 |
| RBM25 | RNA binding motif protein 25 | -0.037783 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0374731 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0372448 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.037086 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0365066 |
| PRDX1 | peroxiredoxin 1 | -0.0364296 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0363877 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0360454 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0360401 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0358842 |
| TPM4 | tropomyosin 4 | -0.0356137 |
| RPL7 | ribosomal protein L7 | -0.0354537 |
| PKM | pyruvate kinase, muscle | -0.0351188 |
| PFDN2 | prefoldin subunit 2 | -0.0337759 |
| S100A11 | S100 calcium binding protein A11 | -0.0335343 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0331778 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0330566 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0327627 |
| RPS25 | ribosomal protein S25 | -0.0322423 |
| KIF5B | kinesin family member 5B | -0.0320837 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0319603 |
| DENND4A | DENN/MADD domain containing 4A | -0.0318316 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.031432 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0314068 |
| MAP1B | microtubule-associated protein 1B | -0.0313554 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0307963 |
| CDCP1 | CUB domain containing protein 1 | -0.0305835 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0300072 |
| CENPF | centromere protein F, 350/400kDa | -0.0299262 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0298398 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0279511 |
| RPLP1 | ribosomal protein, large, P1 | -0.0276873 |
| SERF2 | small EDRK-rich factor 2 | -0.0270847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0267805 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0264186 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0263285 |
| SPAG9 | sperm associated antigen 9 | -0.0262144 |
| RPS12 | ribosomal protein S12 | -0.0257558 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0253566 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0250376 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0247656 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0247389 |
| RPS16 | ribosomal protein S16 | -0.0242474 |
| GRAMD1B | GRAM domain containing 1B | -0.0242465 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0241593 |
| GOLGA4 | golgin A4 | -0.0241184 |
| CLTC | clathrin, heavy chain (Hc) | -0.0240532 |
| LDHB | lactate dehydrogenase B | -0.0234948 |
| AREG | amphiregulin | -0.0232209 |
| USP3 | ubiquitin specific peptidase 3 | -0.0231293 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0230547 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0225873 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0225025 |
| DEK | DEK proto-oncogene | -0.0223201 |
| UPP1 | uridine phosphorylase 1 | -0.0221768 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0218178 |
| RPL4 | ribosomal protein L4 | -0.0218163 |
| LYPLA1 | lysophospholipase I | -0.021764 |
| ZNF292 | zinc finger protein 292 | -0.0216555 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0215485 |
| VMP1 | vacuole membrane protein 1 | -0.0213945 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0211683 |
