Triamcinolone_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Triamcinolone perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Triamcinolone_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EEF2 eukaryotic translation elongation factor 2 0.0631505
HDAC9 histone deacetylase 9 0.0580087
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0516824
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0501245
NONO non-POU domain containing, octamer-binding 0.0432613
AMOTL2 angiomotin like 2 0.0429276
ZFAND3 zinc finger, AN1-type domain 3 0.0425951
ENO2 enolase 2 (gamma, neuronal) 0.0393865
FOXP1 forkhead box P1 0.0391027
NAV2 neuron navigator 2 0.0386507
PLXNA1 plexin A1 0.0340099
MYH9 myosin, heavy chain 9, non-muscle 0.0339074
TSC22D1 TSC22 domain family, member 1 0.0325553
IGF2 insulin-like growth factor 2 0.0319419
PTPRF protein tyrosine phosphatase, receptor type, F 0.0313921
RPS3 ribosomal protein S3 0.0312655
KMT2D lysine (K)-specific methyltransferase 2D 0.0309278
FLNA filamin A, alpha 0.0297005
AKAP12 A kinase (PRKA) anchor protein 12 0.0288311
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.0288107
SEPTIN9 septin 9 0.0286397
ARID1A AT rich interactive domain 1A (SWI-like) 0.0280341
RPS10 ribosomal protein S10 0.0276466
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0271279
FBLN2 fibulin 2 0.0263852
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.0261672
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0253418
CSNK1A1 casein kinase 1, alpha 1 0.0252715
CCNY cyclin Y 0.0252666
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.025198
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0249709
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0246925
N4BP2L2 NEDD4 binding protein 2-like 2 0.0246296
PTPRG protein tyrosine phosphatase, receptor type, G 0.0242238
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0239792
PRRC2A proline-rich coiled-coil 2A 0.0239743
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0235975
SETX senataxin 0.0235753
PUM1 pumilio RNA-binding family member 1 0.0229179
SRSF5 serine/arginine-rich splicing factor 5 0.022834
VEGFA vascular endothelial growth factor A 0.022568
MACF1 microtubule-actin crosslinking factor 1 0.022263
PLK2 polo-like kinase 2 0.0221856
PDGFC platelet derived growth factor C 0.0220668
FER1L6 fer-1-like family member 6 0.0220417
USP25 ubiquitin specific peptidase 25 0.021735
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0215354
BPTF bromodomain PHD finger transcription factor 0.0215294
TMEM131 transmembrane protein 131 0.0214584
CEP250 centrosomal protein 250kDa 0.0212915
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.0212324
CEP112 centrosomal protein 112kDa 0.0210371
FN1 fibronectin 1 0.0210319
TACC2 transforming, acidic coiled-coil containing protein 2 0.0209472
ARHGAP25 Rho GTPase activating protein 25 0.0209429
KLC1 kinesin light chain 1 0.0208968
PDE4D phosphodiesterase 4D, cAMP-specific 0.0208886
CALR calreticulin 0.0208507
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0205099
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0204618
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.0203908
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0203761
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0202776
MKI67 marker of proliferation Ki-67 0.0198102
TPI1 triosephosphate isomerase 1 0.0197967
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0194389
IGFBP3 insulin-like growth factor binding protein 3 0.0192073
JUN jun proto-oncogene 0.0191947
MT2A metallothionein 2A 0.0191457
YLPM1 YLP motif containing 1 0.0190325
ATXN1 ataxin 1 0.0188844
FMNL2 formin-like 2 0.0187462
PDS5B PDS5 cohesin associated factor B 0.0186213
KMT2E lysine (K)-specific methyltransferase 2E 0.0186096
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.018365
SFSWAP splicing factor, suppressor of white-apricot family 0.0183409
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0182082
PITPNB phosphatidylinositol transfer protein, beta 0.0181416
WAC WW domain containing adaptor with coiled-coil 0.0181087
TM4SF1 transmembrane 4 L six family member 1 0.0180859
IRS1 insulin receptor substrate 1 0.0180008
RBMX RNA binding motif protein, X-linked 0.0178589
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.017821
RAB27B RAB27B, member RAS oncogene family 0.0177959
CCDC12 coiled-coil domain containing 12 0.0177906
TOB1 transducer of ERBB2, 1 0.0176872
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0175752
WSB1 WD repeat and SOCS box containing 1 0.0174189
HIRA histone cell cycle regulator 0.0173683
MRTFA myocardin related transcription factor A 0.0172423
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.017213
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0171985
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.0171843
RBM6 RNA binding motif protein 6 0.0171624
SETD5 SET domain containing 5 0.0170912
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0169764
RPL30 ribosomal protein L30 0.0168962
FUS FUS RNA binding protein 0.0168505
KDM4B lysine (K)-specific demethylase 4B 0.0167889
PTK2 protein tyrosine kinase 2 0.0167291

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.210274
AHNAK AHNAK nucleoprotein -0.196173
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.176009
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.12939
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0942595
PTMA prothymosin, alpha -0.0939527
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0930013
RPS6 ribosomal protein S6 -0.0919969
NBEA neurobeachin -0.0824952
GOLGA4 golgin A4 -0.0797136
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0748727
S100A6 S100 calcium binding protein A6 -0.0674715
PGK1 phosphoglycerate kinase 1 -0.0667872
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0646704
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -0.0630429
RPLP1 ribosomal protein, large, P1 -0.0627513
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0611946
LDHA lactate dehydrogenase A -0.0562032
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0558845
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0555799
PKM pyruvate kinase, muscle -0.0546947
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.0540686
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0536708
NFIA nuclear factor I/A -0.0520909
RBM39 RNA binding motif protein 39 -0.051206
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0484895
TMSB4X thymosin beta 4, X-linked -0.0478302
CCND1 cyclin D1 -0.047756
ADAM10 ADAM metallopeptidase domain 10 -0.047548
LCORL ligand dependent nuclear receptor corepressor-like -0.0468294
FLNB filamin B, beta -0.0467688
RPL13A ribosomal protein L13a -0.0461592
NAP1L1 nucleosome assembly protein 1-like 1 -0.0461193
TTC28 tetratricopeptide repeat domain 28 -0.0453725
PNISR PNN-interacting serine/arginine-rich protein -0.0445171
EIF4A2 eukaryotic translation initiation factor 4A2 -0.0430789
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.0418352
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -0.0414936
DLG1 discs, large homolog 1 (Drosophila) -0.041122
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0407577
VCL vinculin -0.0403693
PDE4B phosphodiesterase 4B, cAMP-specific -0.0400032
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0386084
RPL4 ribosomal protein L4 -0.0385407
TMEM135 transmembrane protein 135 -0.0379723
RPL19 ribosomal protein L19 -0.037011
RTN4 reticulon 4 -0.0367225
KPNB1 karyopherin (importin) beta 1 -0.0358296
SENP6 SUMO1/sentrin specific peptidase 6 -0.035688
TPT1 tumor protein, translationally-controlled 1 -0.0353507
NBAS neuroblastoma amplified sequence -0.0352703
TCF12 transcription factor 12 -0.0350596
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0349754
SMNDC1 survival motor neuron domain containing 1 -0.0347726
RPS25 ribosomal protein S25 -0.034572
USP3 ubiquitin specific peptidase 3 -0.034137
RPL31 ribosomal protein L31 -0.034136
CAMKMT calmodulin-lysine N-methyltransferase -0.0333116
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0328308
FHIT fragile histidine triad -0.0327933
RBM25 RNA binding motif protein 25 -0.032775
RPL28 ribosomal protein L28 -0.0327669
ZMYM2 zinc finger, MYM-type 2 -0.0325749
RPS19 ribosomal protein S19 -0.0322749
ANKRD12 ankyrin repeat domain 12 -0.0313428
ACTG1 actin gamma 1 -0.0312376
KDM3A lysine (K)-specific demethylase 3A -0.0311818
NAMPT nicotinamide phosphoribosyltransferase -0.0307785
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0307175
RPL35A ribosomal protein L35a -0.030635
GLS2 glutaminase 2 (liver, mitochondrial) -0.030496
SLC38A2 solute carrier family 38, member 2 -0.0304852
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0302606
RPL34 ribosomal protein L34 -0.029802
PUM2 pumilio RNA-binding family member 2 -0.0297579
TBC1D22A TBC1 domain family, member 22A -0.0297054
MYOF myoferlin -0.0296708
MORF4L2 mortality factor 4 like 2 -0.0296609
SQSTM1 sequestosome 1 -0.0294666
GNAS GNAS complex locus -0.0292836
CALU calumenin -0.0292479
METTL15 methyltransferase like 15 -0.0291061
PICALM phosphatidylinositol binding clathrin assembly protein -0.0287949
COG5 component of oligomeric golgi complex 5 -0.0284384
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0283271
ENO1 enolase 1, (alpha) -0.028285
RRBP1 ribosome binding protein 1 -0.0280898
TAS2R14 taste receptor, type 2, member 14 -0.028026
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0272557
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0271139
SMC5 structural maintenance of chromosomes 5 -0.0269239
PRRC1 proline-rich coiled-coil 1 -0.0268944
MATR3 matrin 3 -0.0266687
SEC24D SEC24 family member D -0.0264868
ASPH aspartate beta-hydroxylase -0.0263059
CDC73 cell division cycle 73 -0.026208
MXI1 MAX interactor 1, dimerization protein -0.0257362
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.025495
ZC3H13 zinc finger CCCH-type containing 13 -0.0252472
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0251125