Triamcinolone_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Triamcinolone perturbation in SW 1088 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Triamcinolone_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.168091
HIP1 huntingtin interacting protein 1 0.0863084
MYH9 myosin, heavy chain 9, non-muscle 0.0801982
TGFBI transforming growth factor, beta-induced, 68kDa 0.0774342
HIPK2 homeodomain interacting protein kinase 2 0.0703079
COL5A1 collagen, type V, alpha 1 0.0686028
EGFR epidermal growth factor receptor 0.0678465
FN1 fibronectin 1 0.0514906
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.04997
PRELID2 PRELI domain containing 2 0.0486868
NAV2 neuron navigator 2 0.0482111
KYNU kynureninase 0.0465671
CDH13 cadherin 13 0.0453759
ABLIM3 actin binding LIM protein family, member 3 0.0441427
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0434414
HMGA2 high mobility group AT-hook 2 0.0430465
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0421788
INTS6 integrator complex subunit 6 0.0414302
ZMYND8 zinc finger, MYND-type containing 8 0.0408312
FNIP1 folliculin interacting protein 1 0.0406919
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0406474
SND1 staphylococcal nuclease and tudor domain containing 1 0.0385372
NRXN3 neurexin 3 0.0382125
PLEC plectin 0.0371252
PRKCA protein kinase C, alpha 0.0367529
FLNA filamin A, alpha 0.0360458
PDLIM5 PDZ and LIM domain 5 0.0358126
GLUL glutamate-ammonia ligase 0.0350407
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.0345073
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0344048
FKBP5 FK506 binding protein 5 0.0331308
N4BP2L2 NEDD4 binding protein 2-like 2 0.0327616
AKAP12 A kinase (PRKA) anchor protein 12 0.0327466
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0313841
ZSWIM6 zinc finger, SWIM-type containing 6 0.0310928
TTC3 tetratricopeptide repeat domain 3 0.0306344
MACF1 microtubule-actin crosslinking factor 1 0.0300691
VEGFA vascular endothelial growth factor A 0.0291238
NCOR2 nuclear receptor corepressor 2 0.0289998
SEC24A SEC24 family member A 0.0288048
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0282991
PTPRM protein tyrosine phosphatase, receptor type, M 0.0277463
DPYD dihydropyrimidine dehydrogenase 0.0276143
ARHGAP24 Rho GTPase activating protein 24 0.0274206
TSC22D3 TSC22 domain family, member 3 0.0271286
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0266522
VCL vinculin 0.0266272
TNIP1 TNFAIP3 interacting protein 1 0.026517
PGM3 phosphoglucomutase 3 0.0265125
ATXN1 ataxin 1 0.0264122
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0263447
CTNND1 catenin (cadherin-associated protein), delta 1 0.0263044
ANLN anillin, actin binding protein 0.0262344
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0261687
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0261073
SAMD4A sterile alpha motif domain containing 4A 0.0258233
JPH2 junctophilin 2 0.0254966
MBNL2 muscleblind-like splicing regulator 2 0.0251126
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0248794
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0247951
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0244058
NAV1 neuron navigator 1 0.024388
GPATCH2L G patch domain containing 2-like 0.0243391
CHD9 chromodomain helicase DNA binding protein 9 0.0243098
KMT2C lysine (K)-specific methyltransferase 2C 0.0238095
UBAP2 ubiquitin associated protein 2 0.0236863
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0234852
EPS8 epidermal growth factor receptor pathway substrate 8 0.0229113
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0229084
ZNF644 zinc finger protein 644 0.0226904
TIMP3 TIMP metallopeptidase inhibitor 3 0.0226702
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.0226349
DST dystonin 0.0225364
COL6A2 collagen, type VI, alpha 2 0.0224317
KDM4B lysine (K)-specific demethylase 4B 0.0224262
FUS FUS RNA binding protein 0.0219954
NBAS neuroblastoma amplified sequence 0.0216831
SOD2 superoxide dismutase 2, mitochondrial 0.0216281
UBE3C ubiquitin protein ligase E3C 0.0216015
AGO3 argonaute RISC catalytic component 3 0.0214027
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0213404
PCNX4 pecanex 4 0.0213158
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0212891
SEC24D SEC24 family member D 0.0211025
MYOF myoferlin 0.0209118
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.0208468
COL7A1 collagen, type VII, alpha 1 0.0208392
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0207603
KAZN kazrin, periplakin interacting protein 0.0207131
FBXO32 F-box protein 32 0.0207112
COPB1 coatomer protein complex, subunit beta 1 0.0206794
ACTN4 actinin, alpha 4 0.0205887
FAM107B family with sequence similarity 107, member B 0.0204538
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0204465
DPYSL2 dihydropyrimidinase-like 2 0.020296
IRS2 insulin receptor substrate 2 0.0202932
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.0202557
ARHGAP5 Rho GTPase activating protein 5 0.0202483
HDAC9 histone deacetylase 9 0.0201327
SEPTIN2 septin 2 0.0200072

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.35976
VIM vimentin -0.147335
TMSB10 thymosin beta 10 -0.132132
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.100354
B2M beta-2-microglobulin -0.0867841
MT2A metallothionein 2A -0.0857475
COL1A1 collagen, type I, alpha 1 -0.0833513
FTL ferritin, light polypeptide -0.0722848
SDC4 syndecan 4 -0.0655972
PTMA prothymosin, alpha -0.0652231
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.062946
ENO1 enolase 1, (alpha) -0.0629046
COL1A2 collagen, type I, alpha 2 -0.0619876
CCNI cyclin I -0.061804
KMT2E lysine (K)-specific methyltransferase 2E -0.0617301
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0592582
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0573256
LDHA lactate dehydrogenase A -0.0550716
IGFBP3 insulin-like growth factor binding protein 3 -0.0540535
CADM1 cell adhesion molecule 1 -0.0536455
ELL2 elongation factor, RNA polymerase II, 2 -0.0523667
UBC ubiquitin C -0.0522472
IL6 interleukin 6 -0.0498455
NAMPT nicotinamide phosphoribosyltransferase -0.0478919
PKM pyruvate kinase, muscle -0.0464279
RTN4 reticulon 4 -0.0453402
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0450161
SMAD3 SMAD family member 3 -0.0445556
ZNF395 zinc finger protein 395 -0.0439661
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0423076
PIAS1 protein inhibitor of activated STAT, 1 -0.0420641
TRIO trio Rho guanine nucleotide exchange factor -0.0414741
RPLP1 ribosomal protein, large, P1 -0.0407593
STC1 stanniocalcin 1 -0.0407276
RPL34 ribosomal protein L34 -0.0371889
NDRG1 N-myc downstream regulated 1 -0.0358231
ECE1 endothelin converting enzyme 1 -0.0353595
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -0.0349379
TXNIP thioredoxin interacting protein -0.0345824
SEPTIN7 septin 7 -0.0345221
CALR calreticulin -0.03445
CD99 CD99 molecule -0.0343684
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0341706
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0338934
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0338308
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.033638
GNAS GNAS complex locus -0.033625
MAP1B microtubule-associated protein 1B -0.0333871
ARRDC3 arrestin domain containing 3 -0.0333401
H3-3B H3.3 histone B -0.0325034
LOX lysyl oxidase -0.0323741
PSD3 pleckstrin and Sec7 domain containing 3 -0.0321502
PCBP2 poly(rC) binding protein 2 -0.0319143
SEC31A SEC31 homolog A (S. cerevisiae) -0.0317178
JUN jun proto-oncogene -0.031573
RAB1A RAB1A, member RAS oncogene family -0.0308218
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0307474
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.030559
ANXA5 annexin A5 -0.0302665
F3 coagulation factor III (thromboplastin, tissue factor) -0.0294642
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0293362
PGK1 phosphoglycerate kinase 1 -0.0291595
CDK6 cyclin-dependent kinase 6 -0.0287028
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0279768
MEF2A myocyte enhancer factor 2A -0.0278509
PTN pleiotrophin -0.0277684
HMGB1 high mobility group box 1 -0.0277482
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0276856
EGR1 early growth response 1 -0.027117
RPL32 ribosomal protein L32 -0.0268059
RSAD2 radical S-adenosyl methionine domain containing 2 -0.026442
DEPP1 DEPP autophagy regulator 1 -0.0262624
SEC23A Sec23 homolog A (S. cerevisiae) -0.0262008
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0259601
ZNF292 zinc finger protein 292 -0.0258831
MARCHF6 membrane associated ring-CH-type finger 6 -0.0252962
SPAG9 sperm associated antigen 9 -0.0252183
NOP58 NOP58 ribonucleoprotein -0.024686
NDUFA4 NDUFA4, mitochondrial complex associated -0.024514
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0244002
RLF rearranged L-myc fusion -0.0243477
RIGI RNA sensor RIG-I -0.0243336
RPS6 ribosomal protein S6 -0.0242658
CD44 CD44 molecule (Indian blood group) -0.0241772
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0241403
BSG basigin (Ok blood group) -0.0241324
VDAC1 voltage-dependent anion channel 1 -0.0240705
POMP proteasome maturation protein -0.0235871
COL6A1 collagen, type VI, alpha 1 -0.023533
ACTG1 actin gamma 1 -0.0234542
BASP1 brain abundant, membrane attached signal protein 1 -0.0232135
CAV1 caveolin 1, caveolae protein, 22kDa -0.0228593
RPS25 ribosomal protein S25 -0.0226201
RRBP1 ribosome binding protein 1 -0.0225991
NF1 neurofibromin 1 -0.0224612
ARID4B AT rich interactive domain 4B (RBP1-like) -0.022405
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0222657
CBX3 chromobox homolog 3 -0.0220893
TUBB tubulin, beta class I -0.0220808
SERF2 small EDRK-rich factor 2 -0.0220683