Triamcinolone_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Triamcinolone perturbation in SW 1271 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Triamcinolone_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
CEP250 centrosomal protein 250kDa 0.0739968
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0704744
MYH9 myosin, heavy chain 9, non-muscle 0.0674021
RBM39 RNA binding motif protein 39 0.0597135
SMYD3 SET and MYND domain containing 3 0.0589546
SQSTM1 sequestosome 1 0.0573103
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0546001
YAP1 Yes-associated protein 1 0.0545113
FUS FUS RNA binding protein 0.0504918
TNIP1 TNFAIP3 interacting protein 1 0.0483967
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0482348
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.047145
ZNF638 zinc finger protein 638 0.0465367
NUMA1 nuclear mitotic apparatus protein 1 0.0444537
MBNL1 muscleblind-like splicing regulator 1 0.0440393
ZMYND8 zinc finger, MYND-type containing 8 0.0438712
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0435673
NAMPT nicotinamide phosphoribosyltransferase 0.0432894
EEF2 eukaryotic translation elongation factor 2 0.0425646
IGF2 insulin-like growth factor 2 0.0425257
FMNL2 formin-like 2 0.0420178
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0417401
PLEC plectin 0.0414168
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0407748
FAM13A family with sequence similarity 13, member A 0.0399098
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.038197
AKAP12 A kinase (PRKA) anchor protein 12 0.0381077
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0380476
WWOX WW domain containing oxidoreductase 0.0373254
ANXA1 annexin A1 0.0367955
HELZ helicase with zinc finger 0.036607
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0365235
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0364105
GPHN gephyrin 0.0358265
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0355173
DSCAM Down syndrome cell adhesion molecule 0.0350892
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0350401
APLP2 amyloid beta (A4) precursor-like protein 2 0.0350235
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0350214
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0337476
FAF1 Fas (TNFRSF6) associated factor 1 0.0326841
MAP2K1 mitogen-activated protein kinase kinase 1 0.0320779
AKAP10 A kinase (PRKA) anchor protein 10 0.0315465
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0313672
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0312801
TRAM2 translocation associated membrane protein 2 0.030405
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0304033
TASOR2 transcription activation suppressor family member 2 0.0302519
OGA O-GlcNAcase 0.0302241
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0297542
PER1 period circadian clock 1 0.0297204
NONO non-POU domain containing, octamer-binding 0.0293309
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0289626
MON2 MON2 homolog (S. cerevisiae) 0.0286299
FLNA filamin A, alpha 0.0285551
RAB5A RAB5A, member RAS oncogene family 0.0284661
XRN1 5'-3' exoribonuclease 1 0.028427
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.0283669
RPS12 ribosomal protein S12 0.0275921
INTS6 integrator complex subunit 6 0.027314
MFGE8 milk fat globule-EGF factor 8 protein 0.0272981
FNDC3A fibronectin type III domain containing 3A 0.0272052
SOD2 superoxide dismutase 2, mitochondrial 0.026972
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0267934
TPST1 tyrosylprotein sulfotransferase 1 0.0265335
KDM4B lysine (K)-specific demethylase 4B 0.0261185
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0261142
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0258619
MED13 mediator complex subunit 13 0.0258272
RNF216 ring finger protein 216 0.0256352
SETD5 SET domain containing 5 0.025553
LHFPL6 LHFPL tetraspan subfamily member 6 0.025444
FRYL FRY-like 0.0253257
CCND3 cyclin D3 0.0252843
CANX calnexin 0.025124
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0248967
KMT2D lysine (K)-specific methyltransferase 2D 0.0248954
HIPK2 homeodomain interacting protein kinase 2 0.0247849
HSPA8 heat shock 70kDa protein 8 0.0245595
MSI2 musashi RNA-binding protein 2 0.024533
RRM2 ribonucleotide reductase M2 0.0244911
NCAPD2 non-SMC condensin I complex, subunit D2 0.0244735
SRRM2 serine/arginine repetitive matrix 2 0.0244023
RBMX RNA binding motif protein, X-linked 0.0243832
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.024256
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0242405
ARID1A AT rich interactive domain 1A (SWI-like) 0.0240044
MARCHF6 membrane associated ring-CH-type finger 6 0.0239615
PRELID2 PRELI domain containing 2 0.0238668
FUBP1 far upstream element (FUSE) binding protein 1 0.0237238
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0237118
CPNE1 copine I 0.0236298
ANKRD17 ankyrin repeat domain 17 0.023607
FN1 fibronectin 1 0.0235634
RPS23 ribosomal protein S23 0.0235504
EIF4B eukaryotic translation initiation factor 4B 0.0235224
TOP1 topoisomerase (DNA) I 0.0235033
ADM adrenomedullin 0.0233166
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.0232917
MATR3 matrin 3 0.0230657

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.388959
VIM vimentin -0.120698
TMSB10 thymosin beta 10 -0.0988448
CD44 CD44 molecule (Indian blood group) -0.0653555
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.0642598
SLC38A2 solute carrier family 38, member 2 -0.0592132
IGFBP3 insulin-like growth factor binding protein 3 -0.0524184
OSMR oncostatin M receptor -0.0468313
ATXN1 ataxin 1 -0.0462009
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0432342
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0432119
RAI14 retinoic acid induced 14 -0.0409905
TM4SF1 transmembrane 4 L six family member 1 -0.0403747
THSD4 thrombospondin, type I, domain containing 4 -0.0403083
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0401688
SDC4 syndecan 4 -0.0391083
MAP1B microtubule-associated protein 1B -0.0386108
NGLY1 N-glycanase 1 -0.0383596
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.037548
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0368083
TXNIP thioredoxin interacting protein -0.0348611
ASPH aspartate beta-hydroxylase -0.0343403
ZBTB20 zinc finger and BTB domain containing 20 -0.0340222
POTEF POTE ankyrin domain family, member F -0.033966
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0337989
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0329357
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.032469
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0319101
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0316977
ZNF292 zinc finger protein 292 -0.0316188
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0316035
BIRC6 baculoviral IAP repeat containing 6 -0.0312104
PCNX4 pecanex 4 -0.0308507
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0305289
CELF1 CUGBP, Elav-like family member 1 -0.0292654
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0291948
ATG7 autophagy related 7 -0.0284018
RTN4 reticulon 4 -0.0281127
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.027911
PALM2AKAP2 PALM2 and AKAP2 fusion -0.027863
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0273911
COG6 component of oligomeric golgi complex 6 -0.0269519
ITPRID2 ITPR interacting domain containing 2 -0.0268287
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0259775
PTMA prothymosin, alpha -0.0257991
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0254973
HJURP Holliday junction recognition protein -0.0254748
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0254378
PRR16 proline rich 16 -0.0252702
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0250608
NAV2 neuron navigator 2 -0.0249842
PRSS23 protease, serine, 23 -0.0249809
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0247725
PCED1B PC-esterase domain containing 1B -0.0247212
ENO2 enolase 2 (gamma, neuronal) -0.0245241
SH3KBP1 SH3-domain kinase binding protein 1 -0.0244532
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0244195
ECT2 epithelial cell transforming 2 -0.0243606
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0242388
PODXL podocalyxin-like -0.0241096
PGK1 phosphoglycerate kinase 1 -0.0239474
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.023873
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0238363
BSG basigin (Ok blood group) -0.0237009
PIAS1 protein inhibitor of activated STAT, 1 -0.0236808
THBS1 thrombospondin 1 -0.0236076
RIN2 Ras and Rab interactor 2 -0.0235904
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0230632
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0229144
RSF1 remodeling and spacing factor 1 -0.0228964
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.022781
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0225816
ACTG1 actin gamma 1 -0.0224163
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0224054
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.0224018
CLIP1 CAP-GLY domain containing linker protein 1 -0.022333
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0219458
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0218689
CDCP1 CUB domain containing protein 1 -0.021775
PBX3 pre-B-cell leukemia homeobox 3 -0.02177
DYNLRB1 dynein, light chain, roadblock-type 1 -0.0217242
LAMB1 laminin, beta 1 -0.0217213
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0216653
AHNAK AHNAK nucleoprotein -0.0213064
FLNB filamin B, beta -0.0212579
NR4A3 nuclear receptor subfamily 4, group A, member 3 -0.0211114
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0210692
GSK3B glycogen synthase kinase 3 beta -0.021033
VCL vinculin -0.0205982
LRRC49 leucine rich repeat containing 49 -0.020575
SEPTIN10 septin 10 -0.0205397
LMNA lamin A/C -0.0205361
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0204359
RPL31 ribosomal protein L31 -0.020405
FTH1 ferritin, heavy polypeptide 1 -0.0201969
ARHGAP18 Rho GTPase activating protein 18 -0.0201035
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0200954
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.0200162
TPM4 tropomyosin 4 -0.0199139
SLC35F3 solute carrier family 35, member F3 -0.0197007