| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Triclosan_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.133867 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.118038 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0792794 |
| CENPF | centromere protein F, 350/400kDa | 0.0733328 |
| ASPH | aspartate beta-hydroxylase | 0.0695937 |
| PLAT | plasminogen activator, tissue | 0.0672553 |
| CDH13 | cadherin 13 | 0.0593955 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0588557 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0571793 |
| HDAC9 | histone deacetylase 9 | 0.0551903 |
| EFNA5 | ephrin-A5 | 0.0520205 |
| MSN | moesin | 0.0478263 |
| ENO1 | enolase 1, (alpha) | 0.0464631 |
| TPM3 | tropomyosin 3 | 0.045441 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0440523 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0437131 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0419342 |
| MYADM | myeloid-associated differentiation marker | 0.0411324 |
| DSPP | dentin sialophosphoprotein | 0.0397655 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0383254 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0374239 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0372805 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0358945 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0353266 |
| SET | SET nuclear proto-oncogene | 0.0343369 |
| FLNB | filamin B, beta | 0.0334297 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0315972 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0311887 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0301253 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0296675 |
| MKI67 | marker of proliferation Ki-67 | 0.0295617 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0293004 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0284584 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0274735 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0274089 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0271132 |
| B2M | beta-2-microglobulin | 0.0271097 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0268382 |
| MCL1 | myeloid cell leukemia 1 | 0.0267634 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0261209 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0259282 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0259273 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0250487 |
| E2F7 | E2F transcription factor 7 | 0.0247716 |
| SEPTIN7 | septin 7 | 0.0245904 |
| CEP170 | centrosomal protein 170kDa | 0.0236782 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0233461 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0232802 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0230331 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.022742 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.022261 |
| ARFGEF3 | ARFGEF family member 3 | 0.0221697 |
| EZR | ezrin | 0.0221542 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0219903 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0217768 |
| EGFR | epidermal growth factor receptor | 0.0217746 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.021569 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0215001 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0212597 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0212512 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0211686 |
| ACER3 | alkaline ceramidase 3 | 0.0208669 |
| ANXA1 | annexin A1 | 0.020193 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0200066 |
| BPTF | bromodomain PHD finger transcription factor | 0.0196071 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0192263 |
| NOTCH2 | notch 2 | 0.0191495 |
| RAI1 | retinoic acid induced 1 | 0.0191455 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0189811 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0183013 |
| POTEF | POTE ankyrin domain family, member F | 0.0182363 |
| PNN | pinin, desmosome associated protein | 0.0180427 |
| TLN1 | talin 1 | 0.017772 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0174907 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0172862 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.017238 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0172114 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0169172 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0165092 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0163449 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0163081 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0160554 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0160246 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0159749 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0159245 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0159108 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0158271 |
| PYGL | phosphorylase, glycogen, liver | 0.0157358 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0157124 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0155198 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0155179 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0155162 |
| VMP1 | vacuole membrane protein 1 | 0.0154679 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0153425 |
| VIM | vimentin | 0.015314 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0149976 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0147623 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0147169 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0146711 |
| DNMBP | dynamin binding protein | 0.0140982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.24611 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.165264 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.117715 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.113773 |
| FBN1 | fibrillin 1 | -0.110129 |
| COL1A2 | collagen, type I, alpha 2 | -0.0992051 |
| NDRG1 | N-myc downstream regulated 1 | -0.0981954 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.09338 |
| LOXL2 | lysyl oxidase-like 2 | -0.0834433 |
| AUTS2 | autism susceptibility candidate 2 | -0.080687 |
| LMNA | lamin A/C | -0.0786697 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0766849 |
| SQSTM1 | sequestosome 1 | -0.0763116 |
| LOX | lysyl oxidase | -0.0748374 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0739186 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0732218 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0730321 |
| CCND1 | cyclin D1 | -0.0726506 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0724164 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0690165 |
| COL3A1 | collagen, type III, alpha 1 | -0.0688441 |
| AHNAK | AHNAK nucleoprotein | -0.0679028 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0672465 |
| MEIS2 | Meis homeobox 2 | -0.0669033 |
| GPC6 | glypican 6 | -0.0662549 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0656567 |
| HLA-B | major histocompatibility complex, class I, B | -0.0647453 |
| COL5A2 | collagen, type V, alpha 2 | -0.0607127 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0575466 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0536789 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0536337 |
| PTMA | prothymosin, alpha | -0.0530542 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0529588 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0528169 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0522658 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0508435 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0483147 |
| MSI2 | musashi RNA-binding protein 2 | -0.0466752 |
| SPAG9 | sperm associated antigen 9 | -0.0465315 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0448581 |
| S100A6 | S100 calcium binding protein A6 | -0.0446743 |
| MAP4 | microtubule-associated protein 4 | -0.0445843 |
| HLA-C | major histocompatibility complex, class I, C | -0.0441823 |
| PRSS23 | protease, serine, 23 | -0.0432543 |
| THBS2 | thrombospondin 2 | -0.0426415 |
| GNAS | GNAS complex locus | -0.0420153 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0416713 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.041541 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0407088 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0405596 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0399702 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0394983 |
| ACTN4 | actinin, alpha 4 | -0.0393074 |
| S100A4 | S100 calcium binding protein A4 | -0.0391948 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.038787 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0387471 |
| ATP13A3 | ATPase type 13A3 | -0.038216 |
| RRBP1 | ribosome binding protein 1 | -0.0382083 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0379429 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0376317 |
| RPL35A | ribosomal protein L35a | -0.037431 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.037256 |
| COL5A1 | collagen, type V, alpha 1 | -0.0372103 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0366638 |
| S100A10 | S100 calcium binding protein A10 | -0.0363707 |
| RIGI | RNA sensor RIG-I | -0.0361919 |
| GOLGA4 | golgin A4 | -0.0360183 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0358167 |
| PXDN | peroxidasin | -0.0354703 |
| WTAP | Wilms tumor 1 associated protein | -0.034768 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343491 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.034301 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0339139 |
| CD99 | CD99 molecule | -0.0338746 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0336583 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0334195 |
| FTL | ferritin, light polypeptide | -0.0333934 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0333606 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0331136 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0329149 |
| NF1 | neurofibromin 1 | -0.0328086 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0326757 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0324725 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0324543 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0323521 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.032315 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0322924 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.032137 |
| INSIG1 | insulin induced gene 1 | -0.0315783 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0315343 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0309153 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0308235 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0307967 |
| TUBB | tubulin, beta class I | -0.0306352 |
| ACTG1 | actin gamma 1 | -0.0305303 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0304066 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0297755 |
| JAZF1 | JAZF zinc finger 1 | -0.0296539 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0291832 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0291191 |
