| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Triclosan_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.184781 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.144 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106077 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0475141 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0428647 |
| PCBP2 | poly(rC) binding protein 2 | 0.0395249 |
| RPS2 | ribosomal protein S2 | 0.0346845 |
| CCNL1 | cyclin L1 | 0.0329498 |
| SET | SET nuclear proto-oncogene | 0.0314629 |
| POTEF | POTE ankyrin domain family, member F | 0.0304924 |
| RPS12 | ribosomal protein S12 | 0.0269902 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0259407 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0256585 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0255113 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0251221 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0246083 |
| BRD2 | bromodomain containing 2 | 0.0245023 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0242712 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.022969 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0224702 |
| PCM1 | pericentriolar material 1 | 0.0213418 |
| TPM3 | tropomyosin 3 | 0.0204617 |
| RPS6 | ribosomal protein S6 | 0.0197359 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0190115 |
| PPID | peptidylprolyl isomerase D | 0.0187218 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0186654 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0183133 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0183088 |
| TUBA1B | tubulin, alpha 1b | 0.0179408 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0176989 |
| UBXN4 | UBX domain protein 4 | 0.0175859 |
| SPAG9 | sperm associated antigen 9 | 0.0175662 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0174588 |
| GOLGA4 | golgin A4 | 0.0173765 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0173612 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0172987 |
| RPL21 | ribosomal protein L21 | 0.0167675 |
| B2M | beta-2-microglobulin | 0.0157954 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0156155 |
| MSN | moesin | 0.0155824 |
| HDGF | hepatoma-derived growth factor | 0.0153934 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0152964 |
| EDN1 | endothelin 1 | 0.0152367 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0151895 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0150757 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0150635 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0150619 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0147498 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0146555 |
| ARF4 | ADP-ribosylation factor 4 | 0.0145952 |
| HOMER1 | homer scaffolding protein 1 | 0.0144093 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0140611 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0139469 |
| SLMAP | sarcolemma associated protein | 0.0139205 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0138375 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0136469 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0134349 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0134341 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0133731 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0133493 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.013216 |
| SCFD1 | sec1 family domain containing 1 | 0.0131054 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.013045 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.012888 |
| MRPL51 | mitochondrial ribosomal protein L51 | 0.012838 |
| CLDND1 | claudin domain containing 1 | 0.0127749 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0126984 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0125779 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.012512 |
| MYADM | myeloid-associated differentiation marker | 0.0122455 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0122138 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0120942 |
| CBX5 | chromobox homolog 5 | 0.0120926 |
| RLF | rearranged L-myc fusion | 0.0119754 |
| MT2A | metallothionein 2A | 0.0119053 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0118882 |
| HTATSF1 | HIV-1 Tat specific factor 1 | 0.0117204 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0116603 |
| CEP70 | centrosomal protein 70kDa | 0.011562 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0114414 |
| PFN1 | profilin 1 | 0.0113446 |
| ENO1 | enolase 1, (alpha) | 0.0113287 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0113262 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0113019 |
| YTHDC1 | YTH domain containing 1 | 0.0112894 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.011286 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0112529 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0112461 |
| NRDC | nardilysin convertase | 0.0111919 |
| SSRP1 | structure specific recognition protein 1 | 0.0111666 |
| CEP152 | centrosomal protein 152kDa | 0.0111116 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0110744 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.01107 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0110275 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0109378 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0108577 |
| NDRG1 | N-myc downstream regulated 1 | 0.0108208 |
| RPS17 | ribosomal protein S17 | 0.0107852 |
| RBM12 | RNA binding motif protein 12 | 0.0106341 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0105873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.299463 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.168362 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.161709 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.15628 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.148759 |
| TMSB10 | thymosin beta 10 | -0.131553 |
| VIM | vimentin | -0.116239 |
| AHNAK | AHNAK nucleoprotein | -0.105139 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.103242 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.102787 |
| PCDH7 | protocadherin 7 | -0.0920794 |
| MMP12 | matrix metallopeptidase 12 | -0.0831652 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0744963 |
| ACTG1 | actin gamma 1 | -0.0730208 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0709291 |
| TENM3 | teneurin transmembrane protein 3 | -0.0656005 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.061901 |
| RPL35A | ribosomal protein L35a | -0.0618833 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0595185 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.059281 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0586864 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0574055 |
| DST | dystonin | -0.0570621 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0545936 |
| LMO7 | LIM domain 7 | -0.054517 |
| NHSL1 | NHS-like 1 | -0.0542013 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0532231 |
| FUS | FUS RNA binding protein | -0.052579 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0517105 |
| PTMA | prothymosin, alpha | -0.0513289 |
| MKI67 | marker of proliferation Ki-67 | -0.0510017 |
| CLDN1 | claudin 1 | -0.0495977 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0480532 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0479126 |
| CCND1 | cyclin D1 | -0.0475621 |
| TMEM123 | transmembrane protein 123 | -0.0458478 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0451201 |
| RPLP1 | ribosomal protein, large, P1 | -0.0445565 |
| SMYD3 | SET and MYND domain containing 3 | -0.0444588 |
| MTAP | methylthioadenosine phosphorylase | -0.0438957 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0423769 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0421065 |
| PDGFC | platelet derived growth factor C | -0.0418302 |
| BCHE | butyrylcholinesterase | -0.0416975 |
| ZNF217 | zinc finger protein 217 | -0.0414291 |
| CANX | calnexin | -0.0411449 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0397445 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0395097 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0382038 |
| H1-0 | H1.0 linker histone | -0.037952 |
| VCL | vinculin | -0.0377585 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0365226 |
| PGK1 | phosphoglycerate kinase 1 | -0.0360641 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0355327 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0353825 |
| GNAS | GNAS complex locus | -0.0352832 |
| ZNF804A | zinc finger protein 804A | -0.0352262 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0348493 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0345412 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0330018 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0328876 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0327588 |
| CMIP | c-Maf inducing protein | -0.032544 |
| EHBP1 | EH domain binding protein 1 | -0.0322703 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0321924 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0321155 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0315377 |
| RPS24 | ribosomal protein S24 | -0.0315057 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0310062 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0308196 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0303763 |
| EDARADD | EDAR-associated death domain | -0.0301667 |
| RBM39 | RNA binding motif protein 39 | -0.0300406 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0300354 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0297565 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0295224 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0289768 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.02897 |
| RPL38 | ribosomal protein L38 | -0.0284285 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0283985 |
| KLF6 | Kruppel-like factor 6 | -0.0279535 |
| XPO1 | exportin 1 | -0.0279048 |
| RPL4 | ribosomal protein L4 | -0.0277434 |
| MGAT4C | MGAT4 family, member C | -0.027625 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0271516 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.027 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.026576 |
| PARK7 | parkinson protein 7 | -0.0262793 |
| VMP1 | vacuole membrane protein 1 | -0.0260158 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0259403 |
| SYT1 | synaptotagmin I | -0.0259052 |
| UBTF | upstream binding transcription factor, RNA polymerase I | -0.0258962 |
| HDLBP | high density lipoprotein binding protein | -0.025754 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0256932 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0255977 |
| MED13L | mediator complex subunit 13-like | -0.0253756 |
| TEAD4 | TEA domain family member 4 | -0.0253257 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0252974 |
| MAP4 | microtubule-associated protein 4 | -0.0251205 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0251126 |
