| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACC1 | metastasis associated in colon cancer 1 | 0.0786956 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.077791 |
| LMO7 | LIM domain 7 | 0.0713467 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0648829 |
| MYO1E | myosin IE | 0.0645657 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.063187 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0630424 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0623371 |
| TMC5 | transmembrane channel-like 5 | 0.0598836 |
| VCL | vinculin | 0.0483663 |
| PLSCR1 | phospholipid scramblase 1 | 0.0463368 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0444878 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0443469 |
| CANX | calnexin | 0.0441258 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0426865 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0423903 |
| ENO1 | enolase 1, (alpha) | 0.0395388 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0394156 |
| GOLGB1 | golgin B1 | 0.0391993 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0391469 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0376676 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0373806 |
| TJP1 | tight junction protein 1 | 0.0369224 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0366445 |
| PHF3 | PHD finger protein 3 | 0.0366396 |
| RIGI | RNA sensor RIG-I | 0.0345072 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0337064 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0336796 |
| FOXP1 | forkhead box P1 | 0.033659 |
| ITGA6 | integrin, alpha 6 | 0.0325345 |
| LCN2 | lipocalin 2 | 0.0322219 |
| STK24 | serine/threonine kinase 24 | 0.0319858 |
| EHBP1 | EH domain binding protein 1 | 0.0312516 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0309205 |
| MECOM | MDS1 and EVI1 complex locus | 0.0307274 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0303148 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0301913 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0301751 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0298527 |
| FHIT | fragile histidine triad | 0.0296971 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0294069 |
| RAD51B | RAD51 paralog B | 0.0293714 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.029112 |
| ATXN1 | ataxin 1 | 0.0289846 |
| ANXA3 | annexin A3 | 0.0288303 |
| NCKAP5 | NCK-associated protein 5 | 0.0283181 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0274904 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0274809 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0274186 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0272778 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0271461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0271086 |
| CDHR2 | cadherin-related family member 2 | 0.0271047 |
| MCU | mitochondrial calcium uniporter | 0.0270605 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0268144 |
| PLCH1 | phospholipase C, eta 1 | 0.0257806 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0246458 |
| AOPEP | aminopeptidase O (putative) | 0.024052 |
| DSTN | destrin (actin depolymerizing factor) | 0.0234933 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0233931 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0231494 |
| SMYD3 | SET and MYND domain containing 3 | 0.0231406 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0231251 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0229566 |
| DSPP | dentin sialophosphoprotein | 0.0227911 |
| YAP1 | Yes-associated protein 1 | 0.0226787 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.0226065 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0224079 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0224047 |
| SPATA13 | spermatogenesis associated 13 | 0.0222325 |
| EREG | epiregulin | 0.0221878 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0215272 |
| CDK6 | cyclin-dependent kinase 6 | 0.0215053 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0214746 |
| RBM26 | RNA binding motif protein 26 | 0.0211412 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0210799 |
| UTRN | utrophin | 0.0210309 |
| JMJD1C | jumonji domain containing 1C | 0.0208696 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0208649 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0207319 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0207296 |
| AATF | apoptosis antagonizing transcription factor | 0.0207035 |
| NEBL | nebulette | 0.0206001 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0205604 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0205571 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0201605 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0200717 |
| ETV6 | ets variant 6 | 0.0200583 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0200395 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0200247 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0199747 |
| CD44 | CD44 molecule (Indian blood group) | 0.0196181 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | 0.0193979 |
| SET | SET nuclear proto-oncogene | 0.0193696 |
| WWOX | WW domain containing oxidoreductase | 0.0193302 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.019305 |
| MEIS2 | Meis homeobox 2 | 0.0192269 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.019215 |
| GALK2 | galactokinase 2 | 0.0191154 |
| ZNF841 | zinc finger protein 841 | 0.0190603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158023 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.123012 |
| NDRG1 | N-myc downstream regulated 1 | -0.102086 |
| HLA-B | major histocompatibility complex, class I, B | -0.0974731 |
| PTMA | prothymosin, alpha | -0.0970857 |
| EGR1 | early growth response 1 | -0.0869248 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0858959 |
| PKM | pyruvate kinase, muscle | -0.0846181 |
| TXNIP | thioredoxin interacting protein | -0.0817675 |
| B2M | beta-2-microglobulin | -0.0767372 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0728594 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.066828 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0633714 |
| RPL35A | ribosomal protein L35a | -0.0633572 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0613608 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0609321 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0581845 |
| FTL | ferritin, light polypeptide | -0.056205 |
| RNF213 | ring finger protein 213 | -0.0557741 |
| MT2A | metallothionein 2A | -0.0542615 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0529539 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0511922 |
| PGK1 | phosphoglycerate kinase 1 | -0.0501534 |
| HLA-A | major histocompatibility complex, class I, A | -0.0494119 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0491682 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.048636 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0480617 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0480003 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0475097 |
| HLA-C | major histocompatibility complex, class I, C | -0.0459372 |
| TMSB10 | thymosin beta 10 | -0.0448949 |
| GNAS | GNAS complex locus | -0.0436476 |
| RPL23 | ribosomal protein L23 | -0.0425173 |
| INTS6 | integrator complex subunit 6 | -0.0420083 |
| PERP | PERP, TP53 apoptosis effector | -0.0416097 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.04137 |
| KRT19 | keratin 19, type I | -0.0411657 |
| ABLIM1 | actin binding LIM protein 1 | -0.038312 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0382287 |
| S100A6 | S100 calcium binding protein A6 | -0.0381595 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0379064 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0371577 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0360612 |
| HLA-E | major histocompatibility complex, class I, E | -0.0360112 |
| RBM39 | RNA binding motif protein 39 | -0.0355329 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.035462 |
| FOXO3 | forkhead box O3 | -0.0353451 |
| ACTG1 | actin gamma 1 | -0.0350178 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0349319 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0348328 |
| SQSTM1 | sequestosome 1 | -0.0346716 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.034175 |
| FNIP1 | folliculin interacting protein 1 | -0.0338632 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0331567 |
| MSI2 | musashi RNA-binding protein 2 | -0.0329922 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.032918 |
| H1-0 | H1.0 linker histone | -0.032219 |
| RNF149 | ring finger protein 149 | -0.0321731 |
| PRKCA | protein kinase C, alpha | -0.0321402 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0319281 |
| RPL19 | ribosomal protein L19 | -0.0318766 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0318435 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0312258 |
| USP53 | ubiquitin specific peptidase 53 | -0.0306971 |
| RPLP1 | ribosomal protein, large, P1 | -0.0306606 |
| UBC | ubiquitin C | -0.0305031 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0304759 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0303389 |
| KIAA1217 | KIAA1217 | -0.0301994 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.030196 |
| DNM2 | dynamin 2 | -0.0301492 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0300879 |
| H3-3B | H3.3 histone B | -0.0299637 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0298635 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0298047 |
| ANXA4 | annexin A4 | -0.0297929 |
| S100A10 | S100 calcium binding protein A10 | -0.0296951 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0296102 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0294384 |
| HMGB1 | high mobility group box 1 | -0.0294173 |
| RPS6 | ribosomal protein S6 | -0.0293827 |
| APOL1 | apolipoprotein L, 1 | -0.0290762 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.028965 |
| RNF43 | ring finger protein 43 | -0.0288296 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0288118 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0285664 |
| HBS1L | HBS1-like translational GTPase | -0.0281946 |
| FOSL2 | FOS-like antigen 2 | -0.0279191 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0278014 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0276737 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0268476 |
| ITGB4 | integrin, beta 4 | -0.0267367 |
| GLO1 | glyoxalase I | -0.02667 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0265722 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0264998 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0263225 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0262589 |
| MXD1 | MAX dimerization protein 1 | -0.0262233 |
| RAB10 | RAB10, member RAS oncogene family | -0.0262058 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0260292 |