| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.115216 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0833918 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0694725 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0691714 |
| ENO1 | enolase 1, (alpha) | 0.0667608 |
| TF | transferrin | 0.0645949 |
| GOLGA4 | golgin A4 | 0.0558629 |
| VEGFA | vascular endothelial growth factor A | 0.0535792 |
| RPL26 | ribosomal protein L26 | 0.0508092 |
| RPL11 | ribosomal protein L11 | 0.046267 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0442085 |
| CRY1 | cryptochrome circadian clock 1 | 0.0428605 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0411277 |
| CPE | carboxypeptidase E | 0.0405971 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0402637 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0393008 |
| RPS3 | ribosomal protein S3 | 0.0386468 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0385377 |
| FAM107B | family with sequence similarity 107, member B | 0.0373761 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0370745 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0368189 |
| RPS6 | ribosomal protein S6 | 0.0346033 |
| DSTN | destrin (actin depolymerizing factor) | 0.0340237 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0333092 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0330736 |
| KLF6 | Kruppel-like factor 6 | 0.0327778 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0327767 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0322026 |
| RPS12 | ribosomal protein S12 | 0.0314024 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.030761 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0304878 |
| RPS2 | ribosomal protein S2 | 0.0299533 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.029948 |
| AFDN | afadin, adherens junction formation factor | 0.0294268 |
| WWC2 | WW and C2 domain containing 2 | 0.0289867 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0289544 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0284601 |
| SMAP1 | small ArfGAP 1 | 0.0280993 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0280963 |
| PRRC2C | proline-rich coiled-coil 2C | 0.028029 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0279161 |
| AHSG | alpha-2-HS-glycoprotein | 0.0275184 |
| QKI | QKI, KH domain containing, RNA binding | 0.0275076 |
| RACK1 | receptor for activated C kinase 1 | 0.0273542 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0269285 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0268456 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0268004 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0254234 |
| EZR | ezrin | 0.0246143 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0245911 |
| RPL37A | ribosomal protein L37a | 0.0240554 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0236629 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0232647 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0230654 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.023057 |
| NGLY1 | N-glycanase 1 | 0.0230336 |
| INSIG2 | insulin induced gene 2 | 0.0229089 |
| LYZ | lysozyme | 0.0222977 |
| MED15 | mediator complex subunit 15 | 0.022287 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.022172 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0220493 |
| PER2 | period circadian clock 2 | 0.0219305 |
| KIF21A | kinesin family member 21A | 0.0218736 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0218254 |
| PDE8A | phosphodiesterase 8A | 0.021731 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0214412 |
| TCIM | transcriptional and immune response regulator | 0.0214216 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0214107 |
| FAM13A | family with sequence similarity 13, member A | 0.0212455 |
| WDR45B | WD repeat domain 45B | 0.0212414 |
| SET | SET nuclear proto-oncogene | 0.021165 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0210229 |
| NUP58 | nucleoporin 58 | 0.0210191 |
| DIAPH1 | diaphanous-related formin 1 | 0.0205488 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0203704 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.020367 |
| RPS8 | ribosomal protein S8 | 0.0202164 |
| RBM33 | RNA binding motif protein 33 | 0.0199748 |
| CCDC146 | coiled-coil domain containing 146 | 0.0198701 |
| UBXN4 | UBX domain protein 4 | 0.0198458 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0195861 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0195725 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0194256 |
| RPS14 | ribosomal protein S14 | 0.0194246 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0192763 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0192339 |
| FAM162A | family with sequence similarity 162, member A | 0.0190341 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0189093 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0188671 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0188428 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0187063 |
| CXXC5 | CXXC finger protein 5 | 0.0186602 |
| RCOR1 | REST corepressor 1 | 0.0186256 |
| SEC24A | SEC24 family member A | 0.0184841 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0184825 |
| ATF4 | activating transcription factor 4 | 0.0184097 |
| NOP58 | NOP58 ribonucleoprotein | 0.0183593 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0181402 |
| SIK3 | SIK family kinase 3 | 0.0180359 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0180247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.195755 |
| MT2A | metallothionein 2A | -0.182095 |
| IGF2 | insulin-like growth factor 2 | -0.150376 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.146713 |
| GPC6 | glypican 6 | -0.1222 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.107196 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.107051 |
| APOA2 | apolipoprotein A-II | -0.102463 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0941978 |
| GPC3 | glypican 3 | -0.0932606 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0848862 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0759651 |
| RPL35A | ribosomal protein L35a | -0.0724259 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0722665 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0714791 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0701542 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0661486 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0650903 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0570434 |
| ATXN1 | ataxin 1 | -0.056766 |
| OSMR | oncostatin M receptor | -0.0542649 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0536615 |
| PARD3 | par-3 family cell polarity regulator | -0.0516938 |
| CP | ceruloplasmin (ferroxidase) | -0.049715 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0488865 |
| EHBP1 | EH domain binding protein 1 | -0.0470296 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0444559 |
| RPLP1 | ribosomal protein, large, P1 | -0.0437663 |
| ATP10A | ATPase, class V, type 10A | -0.0431888 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0425054 |
| FN1 | fibronectin 1 | -0.0423965 |
| TMSB10 | thymosin beta 10 | -0.0412216 |
| RRBP1 | ribosome binding protein 1 | -0.0404217 |
| MRTFA | myocardin related transcription factor A | -0.0401951 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0400809 |
| RPS27A | ribosomal protein S27a | -0.0392363 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0387634 |
| RPL36 | ribosomal protein L36 | -0.0385187 |
| RPL38 | ribosomal protein L38 | -0.0378178 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.037714 |
| SMAD3 | SMAD family member 3 | -0.0373307 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0369714 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0358595 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0353683 |
| FTL | ferritin, light polypeptide | -0.035192 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.034934 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0348697 |
| MSI2 | musashi RNA-binding protein 2 | -0.034796 |
| RPS19 | ribosomal protein S19 | -0.0345963 |
| IL6ST | interleukin 6 signal transducer | -0.0332796 |
| NPR2 | natriuretic peptide receptor 2 | -0.0332506 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0329931 |
| FLNB | filamin B, beta | -0.0324181 |
| KRT8 | keratin 8, type II | -0.0323744 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.032306 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0321512 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0304141 |
| CRLS1 | cardiolipin synthase 1 | -0.0303537 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0301206 |
| RPLP2 | ribosomal protein, large, P2 | -0.0300984 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0298064 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0297874 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0296517 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0295438 |
| CNKSR3 | CNKSR family member 3 | -0.0295088 |
| FOXP1 | forkhead box P1 | -0.0293593 |
| MAP4 | microtubule-associated protein 4 | -0.0293006 |
| HPCAL1 | hippocalcin-like 1 | -0.0291526 |
| FERMT1 | fermitin family member 1 | -0.0289721 |
| ITGA1 | integrin, alpha 1 | -0.0288933 |
| TBCK | TBC1 domain containing kinase | -0.0287265 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0286452 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.028134 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0280638 |
| ACTG1 | actin gamma 1 | -0.0276235 |
| AHNAK | AHNAK nucleoprotein | -0.027389 |
| NHSL1 | NHS-like 1 | -0.0271418 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0268802 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.0267369 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0266084 |
| TPM4 | tropomyosin 4 | -0.0265954 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0265585 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0265056 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0263576 |
| FHIT | fragile histidine triad | -0.0258337 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.025794 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0257871 |
| BCL2L1 | BCL2-like 1 | -0.0257261 |
| IER3 | immediate early response 3 | -0.0252967 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0249627 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0248878 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0248618 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | -0.0247636 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0246303 |
| AOPEP | aminopeptidase O (putative) | -0.024531 |
| HMGA2 | high mobility group AT-hook 2 | -0.0245088 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0244505 |
| PLAC8 | placenta-specific 8 | -0.0244158 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0242808 |
| RPS15 | ribosomal protein S15 | -0.0237937 |
