| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.104812 |
| H1-0 | H1.0 linker histone | 0.103621 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.103251 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0657349 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0639764 |
| EMP1 | epithelial membrane protein 1 | 0.0596031 |
| ANLN | anillin, actin binding protein | 0.0592144 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0573522 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0562911 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0552458 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0551179 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0529034 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0512694 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0507762 |
| RNF213 | ring finger protein 213 | 0.0488936 |
| EZR | ezrin | 0.0487486 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0486055 |
| MKI67 | marker of proliferation Ki-67 | 0.0476796 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0473446 |
| AHR | aryl hydrocarbon receptor | 0.044126 |
| ASPH | aspartate beta-hydroxylase | 0.0434159 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0425815 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0424072 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0423289 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0421838 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0414352 |
| DSPP | dentin sialophosphoprotein | 0.0412701 |
| ECT2 | epithelial cell transforming 2 | 0.040852 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.038422 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0383951 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0375189 |
| CAPN8 | calpain 8 | 0.0374887 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0372687 |
| FAT1 | FAT atypical cadherin 1 | 0.0370396 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0369276 |
| CD2AP | CD2-associated protein | 0.0365407 |
| KRT8 | keratin 8, type II | 0.0363254 |
| LMO7 | LIM domain 7 | 0.0362969 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0359674 |
| PLSCR1 | phospholipid scramblase 1 | 0.0357296 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0346761 |
| XAF1 | XIAP associated factor 1 | 0.034503 |
| AFDN | afadin, adherens junction formation factor | 0.0343783 |
| AHNAK | AHNAK nucleoprotein | 0.0343285 |
| HMGB2 | high mobility group box 2 | 0.034108 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0339703 |
| MX2 | MX dynamin-like GTPase 2 | 0.033581 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0335592 |
| PRKCA | protein kinase C, alpha | 0.0333213 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0330507 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.03304 |
| TMC5 | transmembrane channel-like 5 | 0.0327583 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0324167 |
| CDCP1 | CUB domain containing protein 1 | 0.0323396 |
| FRMD5 | FERM domain containing 5 | 0.0318622 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0308296 |
| USP6NL | USP6 N-terminal like | 0.0307991 |
| FLNB | filamin B, beta | 0.0295673 |
| ANXA2 | annexin A2 | 0.0283674 |
| TCF12 | transcription factor 12 | 0.0282167 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0281905 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0281244 |
| ENO1 | enolase 1, (alpha) | 0.028124 |
| UBB | ubiquitin B | 0.0281046 |
| DIAPH3 | diaphanous-related formin 3 | 0.0274828 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0274502 |
| SP100 | SP100 nuclear antigen | 0.027399 |
| SEPTIN9 | septin 9 | 0.0272881 |
| MTAP | methylthioadenosine phosphorylase | 0.0270272 |
| LAMA4 | laminin, alpha 4 | 0.0269797 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0266153 |
| ETV6 | ets variant 6 | 0.0265841 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.026541 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.026323 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0261971 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0261686 |
| WWOX | WW domain containing oxidoreductase | 0.0259576 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0259502 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0258794 |
| SAMHD1 | SAM domain and HD domain 1 | 0.025599 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0255544 |
| MYO5B | myosin VB | 0.0252831 |
| CENPF | centromere protein F, 350/400kDa | 0.02518 |
| SHROOM3 | shroom family member 3 | 0.0251021 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.025071 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0247847 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0247463 |
| MECOM | MDS1 and EVI1 complex locus | 0.0246621 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.024541 |
| RIGI | RNA sensor RIG-I | 0.0240703 |
| NF1 | neurofibromin 1 | 0.0239439 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0239281 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0238179 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0237942 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0237204 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0233678 |
| TPR | translocated promoter region, nuclear basket protein | 0.0232421 |
| MSI2 | musashi RNA-binding protein 2 | 0.0231975 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0231569 |
| EHBP1 | EH domain binding protein 1 | 0.0227823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.21127 |
| NPSR1 | neuropeptide S receptor 1 | -0.161872 |
| TMSB10 | thymosin beta 10 | -0.149311 |
| RPL35A | ribosomal protein L35a | -0.141032 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.125396 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116342 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0983116 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0937621 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0879389 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0841567 |
| RPS6 | ribosomal protein S6 | -0.0832695 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.080167 |
| PTMA | prothymosin, alpha | -0.0788237 |
| RPL23 | ribosomal protein L23 | -0.0761065 |
| FTL | ferritin, light polypeptide | -0.0745327 |
| VEGFA | vascular endothelial growth factor A | -0.0729027 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0682077 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0644325 |
| S100A6 | S100 calcium binding protein A6 | -0.0552856 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0551719 |
| GOLGA4 | golgin A4 | -0.0548676 |
| RPS25 | ribosomal protein S25 | -0.0539373 |
| WDR45B | WD repeat domain 45B | -0.0538134 |
| NDRG1 | N-myc downstream regulated 1 | -0.0525683 |
| RPS19 | ribosomal protein S19 | -0.0506736 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0502324 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0482122 |
| RPS21 | ribosomal protein S21 | -0.0480379 |
| S100A9 | S100 calcium binding protein A9 | -0.0480342 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0461455 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0449232 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0446606 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0442236 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0438493 |
| AGR2 | anterior gradient 2 | -0.0437765 |
| KLHL29 | kelch-like family member 29 | -0.0434268 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0432995 |
| HM13 | histocompatibility (minor) 13 | -0.0431543 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0429379 |
| HLA-B | major histocompatibility complex, class I, B | -0.0403879 |
| RPS16 | ribosomal protein S16 | -0.0400164 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0399372 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0395731 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0392691 |
| ATXN1 | ataxin 1 | -0.0382417 |
| ITGA6 | integrin, alpha 6 | -0.0370615 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366602 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.036127 |
| RPS5 | ribosomal protein S5 | -0.035948 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0358303 |
| RPL30 | ribosomal protein L30 | -0.0355202 |
| RPL8 | ribosomal protein L8 | -0.0353774 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0351111 |
| PGK1 | phosphoglycerate kinase 1 | -0.034843 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0346103 |
| PCBP2 | poly(rC) binding protein 2 | -0.0344879 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0341524 |
| TES | testin LIM domain protein | -0.0339717 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0334011 |
| ITGB4 | integrin, beta 4 | -0.0332421 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0331999 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0329913 |
| RPL34 | ribosomal protein L34 | -0.032791 |
| RPL7A | ribosomal protein L7a | -0.0327756 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0326715 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0324175 |
| RPS10 | ribosomal protein S10 | -0.0323852 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.032281 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.032096 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0313982 |
| RPL5 | ribosomal protein L5 | -0.0313322 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0311225 |
| SETD5 | SET domain containing 5 | -0.0311052 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0310601 |
| KRT7 | keratin 7, type II | -0.0300042 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0295717 |
| FBXO11 | F-box protein 11 | -0.0293917 |
| RPS8 | ribosomal protein S8 | -0.0291658 |
| PFN1 | profilin 1 | -0.0291371 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0289049 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0288225 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0287619 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0282568 |
| PKM | pyruvate kinase, muscle | -0.028165 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.028152 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0278516 |
| RPS11 | ribosomal protein S11 | -0.027674 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0274822 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0271853 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0271154 |
| MUC1 | mucin 1, cell surface associated | -0.0268853 |
| RPL19 | ribosomal protein L19 | -0.0267423 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0266133 |
| S100A11 | S100 calcium binding protein A11 | -0.0265419 |
| RPS29 | ribosomal protein S29 | -0.026461 |
| ACTG1 | actin gamma 1 | -0.026359 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0263199 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0258771 |
| USP34 | ubiquitin specific peptidase 34 | -0.0257966 |
| CCNL1 | cyclin L1 | -0.0257545 |