| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Triclosan_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0833758 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0790908 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0786528 |
| GPHN | gephyrin | 0.0639351 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0567474 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0551662 |
| EREG | epiregulin | 0.05016 |
| RPL26 | ribosomal protein L26 | 0.0496591 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0491476 |
| VCL | vinculin | 0.0463578 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0462208 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.040982 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0376891 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0356863 |
| TRIM2 | tripartite motif containing 2 | 0.0354614 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0349308 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0344627 |
| ETNK1 | ethanolamine kinase 1 | 0.0342034 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0323626 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0322854 |
| RNF43 | ring finger protein 43 | 0.0320371 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0319477 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0313889 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0311107 |
| CD44 | CD44 molecule (Indian blood group) | 0.0300815 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0298612 |
| DSG2 | desmoglein 2 | 0.0290486 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0289893 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.028879 |
| B2M | beta-2-microglobulin | 0.0288241 |
| PKP2 | plakophilin 2 | 0.0287599 |
| RPS3 | ribosomal protein S3 | 0.0283562 |
| MACC1 | metastasis associated in colon cancer 1 | 0.028237 |
| AREG | amphiregulin | 0.0275276 |
| MLEC | malectin | 0.0274104 |
| CAB39 | calcium binding protein 39 | 0.0263985 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0261699 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0261509 |
| TFRC | transferrin receptor | 0.0260824 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0260531 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0259611 |
| CENPF | centromere protein F, 350/400kDa | 0.0259163 |
| MYO1D | myosin ID | 0.02545 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0253631 |
| ENO1 | enolase 1, (alpha) | 0.0253101 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0251374 |
| WDR43 | WD repeat domain 43 | 0.0248725 |
| KIF5B | kinesin family member 5B | 0.0245282 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0244612 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0241519 |
| PRSS3 | protease, serine, 3 | 0.0241406 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0240348 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0240088 |
| ABHD17C | abhydrolase domain containing 17C | 0.0239713 |
| TNS4 | tensin 4 | 0.0236958 |
| RPS12 | ribosomal protein S12 | 0.0235052 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0233911 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0232376 |
| SHROOM3 | shroom family member 3 | 0.0231534 |
| PCDHB16 | protocadherin beta 16 | 0.0230202 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0226695 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0225621 |
| CADPS | Ca++-dependent secretion activator | 0.02245 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0223592 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0221334 |
| SET | SET nuclear proto-oncogene | 0.0221234 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0219746 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0219178 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0216589 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0216224 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0214981 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0213914 |
| ATP13A3 | ATPase type 13A3 | 0.0209655 |
| RPL11 | ribosomal protein L11 | 0.0209479 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0208814 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0208315 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0207874 |
| MYOF | myoferlin | 0.0205452 |
| MECOM | MDS1 and EVI1 complex locus | 0.0204973 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0204913 |
| NEK7 | NIMA-related kinase 7 | 0.0202331 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0202118 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0201399 |
| LIPH | lipase, member H | 0.0197454 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0196774 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0196434 |
| KIAA1217 | KIAA1217 | 0.0196292 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0195575 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.019215 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0190886 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0189341 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0188918 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0188066 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0185544 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0185154 |
| CARD16 | caspase recruitment domain family, member 16 | 0.018482 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0183108 |
| CDK6 | cyclin-dependent kinase 6 | 0.0182673 |
| EPCAM | epithelial cell adhesion molecule | 0.0181442 |
| KLF6 | Kruppel-like factor 6 | 0.0179659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229251 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.222395 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.167576 |
| TMSB10 | thymosin beta 10 | -0.145154 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.140107 |
| NDRG1 | N-myc downstream regulated 1 | -0.112552 |
| FLNB | filamin B, beta | -0.0876082 |
| MT2A | metallothionein 2A | -0.0846535 |
| LMO7 | LIM domain 7 | -0.0800436 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.078622 |
| ITGA6 | integrin, alpha 6 | -0.0782307 |
| TXNIP | thioredoxin interacting protein | -0.0744145 |
| PKM | pyruvate kinase, muscle | -0.0726972 |
| RPL35A | ribosomal protein L35a | -0.0716532 |
| VEGFA | vascular endothelial growth factor A | -0.0703145 |
| FTL | ferritin, light polypeptide | -0.0691818 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0689532 |
| RPS6 | ribosomal protein S6 | -0.0670615 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0667377 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0660603 |
| AHNAK | AHNAK nucleoprotein | -0.0659488 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0653542 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.06416 |
| RPLP1 | ribosomal protein, large, P1 | -0.0621217 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0614295 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0612039 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0604514 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0602437 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0567181 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.054162 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0540223 |
| TPM4 | tropomyosin 4 | -0.0536196 |
| MUC17 | mucin 17, cell surface associated | -0.0533542 |
| EZR | ezrin | -0.0531969 |
| S100A6 | S100 calcium binding protein A6 | -0.052951 |
| PARD3 | par-3 family cell polarity regulator | -0.0517327 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0517276 |
| MED13 | mediator complex subunit 13 | -0.0510228 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0504233 |
| SVIL | supervillin | -0.0501652 |
| NPSR1 | neuropeptide S receptor 1 | -0.048137 |
| KRT18 | keratin 18, type I | -0.0472087 |
| LDHA | lactate dehydrogenase A | -0.046881 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0463139 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0461663 |
| CALR | calreticulin | -0.0454528 |
| DIAPH2 | diaphanous-related formin 2 | -0.0454488 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0450114 |
| LMNA | lamin A/C | -0.0448433 |
| RPL8 | ribosomal protein L8 | -0.0439181 |
| FBXO11 | F-box protein 11 | -0.0426645 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0423492 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0422192 |
| ASPH | aspartate beta-hydroxylase | -0.0416273 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0414711 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0413808 |
| FAM13A | family with sequence similarity 13, member A | -0.0407674 |
| AGR2 | anterior gradient 2 | -0.040467 |
| RPS19 | ribosomal protein S19 | -0.0402674 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0402237 |
| KRT8 | keratin 8, type II | -0.0402201 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0401807 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0390763 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.038991 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0389166 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.038904 |
| RPL19 | ribosomal protein L19 | -0.0383235 |
| S100A9 | S100 calcium binding protein A9 | -0.0379255 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.037388 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0367553 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0365221 |
| SPAG9 | sperm associated antigen 9 | -0.0364056 |
| EGFR | epidermal growth factor receptor | -0.0363622 |
| CCNY | cyclin Y | -0.0362899 |
| GLG1 | golgi glycoprotein 1 | -0.0356772 |
| ACTG1 | actin gamma 1 | -0.0356201 |
| KRT19 | keratin 19, type I | -0.0351761 |
| ZNF292 | zinc finger protein 292 | -0.0347426 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0346387 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0346298 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0343043 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0341919 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0341283 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0339872 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0338509 |
| RPS29 | ribosomal protein S29 | -0.0330507 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0329037 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328279 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0327728 |
| USP53 | ubiquitin specific peptidase 53 | -0.0327536 |
| YBX1 | Y box binding protein 1 | -0.0324417 |
| MT1X | metallothionein 1X | -0.0321372 |
| RPS27 | ribosomal protein S27 | -0.0320735 |
| RPS11 | ribosomal protein S11 | -0.0317908 |
| ACTN4 | actinin, alpha 4 | -0.0314776 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0313424 |
| ERBIN | erbb2 interacting protein | -0.0311807 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0308803 |
| MYO1E | myosin IE | -0.0308243 |
| CLOCK | clock circadian regulator | -0.030642 |
