| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.0744543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0667606 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0656803 |
| RPS12 | ribosomal protein S12 | 0.0615011 |
| RPL26 | ribosomal protein L26 | 0.0611066 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0568522 |
| ENO1 | enolase 1, (alpha) | 0.0534588 |
| RPS6 | ribosomal protein S6 | 0.0531632 |
| RPS8 | ribosomal protein S8 | 0.0526167 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0506485 |
| RPL37A | ribosomal protein L37a | 0.0501781 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0479822 |
| B2M | beta-2-microglobulin | 0.0466705 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0444711 |
| TP63 | tumor protein p63 | 0.0440632 |
| RPS3 | ribosomal protein S3 | 0.0432769 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0427568 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0411792 |
| RPL12 | ribosomal protein L12 | 0.0409186 |
| SET | SET nuclear proto-oncogene | 0.0404713 |
| TMSB4X | thymosin beta 4, X-linked | 0.038973 |
| RPL37 | ribosomal protein L37 | 0.038569 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0379362 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0367037 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0366943 |
| RPL23 | ribosomal protein L23 | 0.0343301 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0338836 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0338335 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0331992 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0327501 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0307534 |
| CADM2 | cell adhesion molecule 2 | 0.0304723 |
| CAPRIN2 | caprin family member 2 | 0.0304505 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0296548 |
| RPL36 | ribosomal protein L36 | 0.0288637 |
| EREG | epiregulin | 0.0286398 |
| RPL11 | ribosomal protein L11 | 0.02827 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0273517 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0268712 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0267741 |
| RPS19 | ribosomal protein S19 | 0.0265141 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0258221 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0249593 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0247255 |
| MATR3 | matrin 3 | 0.0246973 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0242644 |
| RPL31 | ribosomal protein L31 | 0.0239933 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0236898 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0235398 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0233391 |
| TPR | translocated promoter region, nuclear basket protein | 0.0232147 |
| WDR43 | WD repeat domain 43 | 0.0230789 |
| CDK6 | cyclin-dependent kinase 6 | 0.0229612 |
| RACK1 | receptor for activated C kinase 1 | 0.0229392 |
| SYAP1 | synapse associated protein 1 | 0.0228997 |
| PTMA | prothymosin, alpha | 0.0224427 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0222456 |
| ANGPTL4 | angiopoietin-like 4 | 0.0220233 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0218144 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0217644 |
| PDE10A | phosphodiesterase 10A | 0.0213215 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0206094 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0205729 |
| HLA-A | major histocompatibility complex, class I, A | 0.0199428 |
| DPH6 | diphthamine biosynthesis 6 | 0.0195859 |
| RPS2 | ribosomal protein S2 | 0.0195829 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.019548 |
| CRY1 | cryptochrome circadian clock 1 | 0.0193223 |
| PLK2 | polo-like kinase 2 | 0.0192111 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0191503 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0185162 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0184968 |
| ATP13A3 | ATPase type 13A3 | 0.0183249 |
| RPL27 | ribosomal protein L27 | 0.0182397 |
| DIAPH1 | diaphanous-related formin 1 | 0.0180496 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0176363 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0175225 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0173158 |
| H1-0 | H1.0 linker histone | 0.0172032 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0170388 |
| RPS17 | ribosomal protein S17 | 0.0170044 |
| EHBP1 | EH domain binding protein 1 | 0.016425 |
| DNER | delta/notch-like EGF repeat containing | 0.0164181 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0164013 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0162721 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0161801 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0160945 |
| CEP350 | centrosomal protein 350kDa | 0.015906 |
| JUN | jun proto-oncogene | 0.0158561 |
| STMN1 | stathmin 1 | 0.0158465 |
| EZR | ezrin | 0.0152848 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0151946 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0151644 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0151511 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0149355 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0148916 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0148185 |
| RPL14 | ribosomal protein L14 | 0.0146136 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0145888 |
| RPL36A | ribosomal protein L36a | 0.0145742 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.446942 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0919156 |
| MT2A | metallothionein 2A | -0.089518 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0865427 |
| VIM | vimentin | -0.0692757 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0685729 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0560258 |
| ACTG1 | actin gamma 1 | -0.05164 |
| TMSB10 | thymosin beta 10 | -0.0499028 |
| MT1X | metallothionein 1X | -0.0496511 |
| TXNRD1 | thioredoxin reductase 1 | -0.0495362 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0490726 |
| POTEF | POTE ankyrin domain family, member F | -0.0478869 |
| EGR1 | early growth response 1 | -0.0476956 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0456683 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.044481 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0428798 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0425692 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0406826 |
| RPL35A | ribosomal protein L35a | -0.0383609 |
| USP34 | ubiquitin specific peptidase 34 | -0.038149 |
| TXNIP | thioredoxin interacting protein | -0.037844 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.036683 |
| MYOF | myoferlin | -0.0365005 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.034562 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0337425 |
| EMP1 | epithelial membrane protein 1 | -0.0329597 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0319979 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0310499 |
| PKM | pyruvate kinase, muscle | -0.0310193 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0305096 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0303923 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0299603 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0291393 |
| FNIP1 | folliculin interacting protein 1 | -0.028954 |
| SPAG9 | sperm associated antigen 9 | -0.0279475 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0277307 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0276124 |
| RPL8 | ribosomal protein L8 | -0.0275816 |
| HDLBP | high density lipoprotein binding protein | -0.0273864 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0272667 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0269134 |
| FTL | ferritin, light polypeptide | -0.0266182 |
| JMJD1C | jumonji domain containing 1C | -0.0261264 |
| SNX14 | sorting nexin 14 | -0.0256692 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0256254 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0254316 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0254278 |
| FLNB | filamin B, beta | -0.0253979 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0248604 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0247607 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0247227 |
| ZNF217 | zinc finger protein 217 | -0.0245921 |
| TAOK1 | TAO kinase 1 | -0.0245026 |
| RPS23 | ribosomal protein S23 | -0.024152 |
| S100A10 | S100 calcium binding protein A10 | -0.0241496 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0239799 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0238742 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0238687 |
| TAPBP | TAP binding protein (tapasin) | -0.0236848 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.023571 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0234747 |
| LDHA | lactate dehydrogenase A | -0.0234141 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0230183 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0229577 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0229447 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0227998 |
| POM121 | POM121 transmembrane nucleoporin | -0.0227899 |
| CENPF | centromere protein F, 350/400kDa | -0.0227467 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0223026 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0222495 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0219614 |
| PCBP2 | poly(rC) binding protein 2 | -0.0219537 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0215357 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0215356 |
| RCOR1 | REST corepressor 1 | -0.0213907 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0212524 |
| WASF2 | WAS protein family, member 2 | -0.0212482 |
| ANXA1 | annexin A1 | -0.0212189 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211553 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0211428 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0210308 |
| SON | SON DNA binding protein | -0.0208143 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0207984 |
| INTS6 | integrator complex subunit 6 | -0.0207266 |
| MYADM | myeloid-associated differentiation marker | -0.0206639 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0205783 |
| SBF2 | SET binding factor 2 | -0.0204166 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0202539 |
| KIAA1958 | KIAA1958 | -0.0201848 |
| YEATS2 | YEATS domain containing 2 | -0.0199062 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0196269 |
| WDR26 | WD repeat domain 26 | -0.0196016 |
| MYO10 | myosin X | -0.0194144 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0193109 |
| LOXL2 | lysyl oxidase-like 2 | -0.0192364 |
| PODXL | podocalyxin-like | -0.0191562 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0191542 |
| TMEM41B | transmembrane protein 41B | -0.0190281 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0189072 |
