| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.0947263 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0568169 |
| GRAMD1B | GRAM domain containing 1B | 0.0557533 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0490563 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0481372 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0402103 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0398435 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0360418 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0339387 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0315928 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0313368 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0307953 |
| TOP1 | topoisomerase (DNA) I | 0.0306334 |
| LAMA4 | laminin, alpha 4 | 0.0295274 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0294838 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0294592 |
| TES | testin LIM domain protein | 0.0288603 |
| TJP1 | tight junction protein 1 | 0.0283879 |
| SYAP1 | synapse associated protein 1 | 0.0276827 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0272685 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0257807 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0242517 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0239143 |
| BMP6 | bone morphogenetic protein 6 | 0.0238063 |
| MSN | moesin | 0.0237102 |
| AREG | amphiregulin | 0.0230991 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0230401 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0226367 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0226007 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0224808 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0222954 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.021939 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0210466 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0206204 |
| STC1 | stanniocalcin 1 | 0.0204277 |
| JMJD1C | jumonji domain containing 1C | 0.0200657 |
| RTN4 | reticulon 4 | 0.0200262 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0198201 |
| SPAG9 | sperm associated antigen 9 | 0.0195219 |
| RUNX1 | runt-related transcription factor 1 | 0.0192199 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0188588 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0187422 |
| IRS2 | insulin receptor substrate 2 | 0.0187302 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.01798 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0179768 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0179316 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0179221 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0178065 |
| MT2A | metallothionein 2A | 0.0172372 |
| YBX3 | Y box binding protein 3 | 0.0163761 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0161134 |
| HOMER1 | homer scaffolding protein 1 | 0.0160969 |
| SON | SON DNA binding protein | 0.0159934 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0158771 |
| YTHDC1 | YTH domain containing 1 | 0.0151768 |
| SIK3 | SIK family kinase 3 | 0.0151763 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0151465 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0150775 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0148309 |
| SGMS2 | sphingomyelin synthase 2 | 0.0148084 |
| EZR | ezrin | 0.0146692 |
| MYOF | myoferlin | 0.0145183 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0144013 |
| FAT1 | FAT atypical cadherin 1 | 0.0142353 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0142303 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0141974 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0140062 |
| DST | dystonin | 0.0137461 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0133903 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0133342 |
| TMF1 | TATA element modulatory factor 1 | 0.0133028 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0131782 |
| SMYD3 | SET and MYND domain containing 3 | 0.0131558 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0130872 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0128422 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0127777 |
| RPS2 | ribosomal protein S2 | 0.0125715 |
| PNN | pinin, desmosome associated protein | 0.0124733 |
| NME7 | NME/NM23 family member 7 | 0.0124029 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0123621 |
| RPS12 | ribosomal protein S12 | 0.0123163 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0120648 |
| ATXN1 | ataxin 1 | 0.0120323 |
| MYO5B | myosin VB | 0.0119067 |
| UBE3A | ubiquitin protein ligase E3A | 0.01185 |
| OXSR1 | oxidative stress responsive 1 | 0.0117129 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0117032 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0115533 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0115075 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0114192 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0113933 |
| EXOC6B | exocyst complex component 6B | 0.0112325 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0112109 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0111232 |
| DIAPH1 | diaphanous-related formin 1 | 0.0111052 |
| TPM3 | tropomyosin 3 | 0.0110607 |
| KLF6 | Kruppel-like factor 6 | 0.0109846 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0109682 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0109662 |
| AHR | aryl hydrocarbon receptor | 0.0109263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.300403 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.275934 |
| EGFR | epidermal growth factor receptor | -0.211737 |
| TMSB10 | thymosin beta 10 | -0.207708 |
| TXNRD1 | thioredoxin reductase 1 | -0.143858 |
| PTMA | prothymosin, alpha | -0.115275 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.102187 |
| ACTG1 | actin gamma 1 | -0.0931728 |
| RPL35A | ribosomal protein L35a | -0.0849519 |
| PKM | pyruvate kinase, muscle | -0.0818639 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0793249 |
| S100A10 | S100 calcium binding protein A10 | -0.0787148 |
| NDRG1 | N-myc downstream regulated 1 | -0.0755176 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.075485 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0751369 |
| FTL | ferritin, light polypeptide | -0.0656803 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0649284 |
| CST3 | cystatin C | -0.0643252 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.06169 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0602046 |
| RPS25 | ribosomal protein S25 | -0.058993 |
| EFNA5 | ephrin-A5 | -0.0561954 |
| AHNAK | AHNAK nucleoprotein | -0.0551326 |
| RPLP1 | ribosomal protein, large, P1 | -0.0542558 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0539629 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0520954 |
| KRT7 | keratin 7, type II | -0.0514696 |
| HDLBP | high density lipoprotein binding protein | -0.0509738 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0500759 |
| ASPH | aspartate beta-hydroxylase | -0.049029 |
| ANXA2 | annexin A2 | -0.0481971 |
| RPS24 | ribosomal protein S24 | -0.0475165 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0475022 |
| LOC112694756 | uncharaterized LOC112694756 | -0.046865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0466883 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0463626 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0449819 |
| PGK1 | phosphoglycerate kinase 1 | -0.0440899 |
| WASF2 | WAS protein family, member 2 | -0.0439064 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.043296 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0431861 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0429398 |
| RPL34 | ribosomal protein L34 | -0.0422062 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0421886 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0420758 |
| HLA-B | major histocompatibility complex, class I, B | -0.0419858 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0414692 |
| H1-0 | H1.0 linker histone | -0.0409396 |
| SMAD3 | SMAD family member 3 | -0.0409205 |
| TMEM165 | transmembrane protein 165 | -0.0405128 |
| CCND1 | cyclin D1 | -0.0396659 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0392157 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0386451 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.038509 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0380071 |
| GPC6 | glypican 6 | -0.0365391 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0365229 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0363127 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0362608 |
| S100A9 | S100 calcium binding protein A9 | -0.0361054 |
| TRIM56 | tripartite motif containing 56 | -0.0358341 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0357828 |
| RPS23 | ribosomal protein S23 | -0.0357021 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0357015 |
| RPL31 | ribosomal protein L31 | -0.0356832 |
| IER3 | immediate early response 3 | -0.0353396 |
| S100A11 | S100 calcium binding protein A11 | -0.035065 |
| PDE8A | phosphodiesterase 8A | -0.0347462 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0340406 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.033941 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.03393 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0335821 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0328172 |
| RPS27A | ribosomal protein S27a | -0.0327044 |
| SEC61G | Sec61 gamma subunit | -0.0323891 |
| RIN2 | Ras and Rab interactor 2 | -0.0323466 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0323295 |
| RPS29 | ribosomal protein S29 | -0.0321798 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0318577 |
| KRT8 | keratin 8, type II | -0.0317111 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0316729 |
| ATG7 | autophagy related 7 | -0.0315962 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0314216 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.031332 |
| SBF2 | SET binding factor 2 | -0.0312559 |
| RPL8 | ribosomal protein L8 | -0.0308419 |
| AGR2 | anterior gradient 2 | -0.0307923 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0305788 |
| FBXO11 | F-box protein 11 | -0.030223 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0294217 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0292941 |
| EGR1 | early growth response 1 | -0.0291848 |
| GNAS | GNAS complex locus | -0.0291585 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0287999 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0287969 |
| RAB10 | RAB10, member RAS oncogene family | -0.0287457 |
| CUX1 | cut-like homeobox 1 | -0.0281238 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0281046 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0279984 |
| LDHA | lactate dehydrogenase A | -0.0279703 |
