| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Triclosan_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0953311 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.073749 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0715697 |
| FMNL2 | formin-like 2 | 0.0667738 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.066292 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0561397 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0510599 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0490103 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0483854 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0440884 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0429938 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0424617 |
| RBM25 | RNA binding motif protein 25 | 0.0419111 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0416543 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.039344 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0384473 |
| PRRC2C | proline-rich coiled-coil 2C | 0.037061 |
| BRD2 | bromodomain containing 2 | 0.036637 |
| MSN | moesin | 0.0364492 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0356509 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0353311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0345225 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0344306 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0342034 |
| NDRG1 | N-myc downstream regulated 1 | 0.0333699 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0329161 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0321722 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0321336 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0321053 |
| MYO1E | myosin IE | 0.0308627 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0305643 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0304261 |
| ATXN1 | ataxin 1 | 0.0301663 |
| STC1 | stanniocalcin 1 | 0.0289962 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0284119 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0283916 |
| CCNL1 | cyclin L1 | 0.0282669 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0280233 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0276874 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0270479 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0268696 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0266064 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0265944 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0263262 |
| RNF145 | ring finger protein 145 | 0.0253851 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0252358 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0252275 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0252211 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0249172 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0248959 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0245177 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.02413 |
| GOLGB1 | golgin B1 | 0.0239732 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0238264 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0234969 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0234676 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0232667 |
| ITSN2 | intersectin 2 | 0.0230892 |
| CD44 | CD44 molecule (Indian blood group) | 0.022872 |
| ANO6 | anoctamin 6 | 0.0224821 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.022479 |
| COPA | coatomer protein complex, subunit alpha | 0.0224189 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0223461 |
| PRKD1 | protein kinase D1 | 0.0223412 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0220714 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0220102 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0218887 |
| DIAPH1 | diaphanous-related formin 1 | 0.0217235 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0216942 |
| INHBA | inhibin, beta A | 0.0215404 |
| PCBP2 | poly(rC) binding protein 2 | 0.0214533 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0214393 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0213261 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0211593 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0211479 |
| SON | SON DNA binding protein | 0.0207227 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0204054 |
| USP36 | ubiquitin specific peptidase 36 | 0.0202066 |
| HLA-A | major histocompatibility complex, class I, A | 0.0201434 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0201422 |
| KIF13A | kinesin family member 13A | 0.0199861 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0199672 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0199286 |
| CCNY | cyclin Y | 0.0199107 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0199001 |
| MYO1B | myosin IB | 0.0198943 |
| B2M | beta-2-microglobulin | 0.01974 |
| INTS6 | integrator complex subunit 6 | 0.0192742 |
| FAM107B | family with sequence similarity 107, member B | 0.0192404 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0192146 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0191658 |
| VIM | vimentin | 0.0191279 |
| TMF1 | TATA element modulatory factor 1 | 0.0190607 |
| CENPF | centromere protein F, 350/400kDa | 0.0189891 |
| CUL3 | cullin 3 | 0.0189378 |
| PRELID2 | PRELI domain containing 2 | 0.0188741 |
| UTRN | utrophin | 0.0188422 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0188397 |
| HLA-B | major histocompatibility complex, class I, B | 0.0188269 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0187773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216926 |
| TXNRD1 | thioredoxin reductase 1 | -0.203845 |
| GRAMD1B | GRAM domain containing 1B | -0.184838 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.130292 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.12934 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.105249 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.10081 |
| TMSB10 | thymosin beta 10 | -0.0903223 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0711859 |
| ACTG1 | actin gamma 1 | -0.064554 |
| RPL4 | ribosomal protein L4 | -0.0567004 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0558848 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0550778 |
| RPL19 | ribosomal protein L19 | -0.0521395 |
| EGR1 | early growth response 1 | -0.0508943 |
| RPLP1 | ribosomal protein, large, P1 | -0.049757 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0490774 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0488329 |
| TPM4 | tropomyosin 4 | -0.0487674 |
| BICC1 | BicC family RNA binding protein 1 | -0.0468326 |
| MT2A | metallothionein 2A | -0.0454562 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0446573 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0443847 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0438771 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0437274 |
| OSMR | oncostatin M receptor | -0.0427598 |
| AHNAK | AHNAK nucleoprotein | -0.0418354 |
| HDAC9 | histone deacetylase 9 | -0.0409755 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0396208 |
| PTMA | prothymosin, alpha | -0.0392043 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0377168 |
| RTN4 | reticulon 4 | -0.036903 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0367836 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0364665 |
| PFDN2 | prefoldin subunit 2 | -0.0349416 |
| KPNB1 | karyopherin (importin) beta 1 | -0.033795 |
| NTN4 | netrin 4 | -0.0336837 |
| RPL8 | ribosomal protein L8 | -0.0333226 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.033322 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.033212 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0330132 |
| RPL35A | ribosomal protein L35a | -0.0329212 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0326786 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0322956 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0317587 |
| HSPA8 | heat shock 70kDa protein 8 | -0.031357 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.030675 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0305655 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0303125 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0302872 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0300903 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0293681 |
| TMEM123 | transmembrane protein 123 | -0.0288659 |
| NAV3 | neuron navigator 3 | -0.0287207 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0286867 |
| SVIL | supervillin | -0.0286543 |
| RPS29 | ribosomal protein S29 | -0.0279422 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0279356 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0274424 |
| IGF2 | insulin-like growth factor 2 | -0.0273763 |
| AK1 | adenylate kinase 1 | -0.0273471 |
| ASPH | aspartate beta-hydroxylase | -0.0259525 |
| RHEB | Ras homolog enriched in brain | -0.0258276 |
| VMP1 | vacuole membrane protein 1 | -0.0252759 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0252716 |
| DENND4A | DENN/MADD domain containing 4A | -0.0252568 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0251046 |
| RPS21 | ribosomal protein S21 | -0.0243019 |
| SLC38A1 | solute carrier family 38, member 1 | -0.024103 |
| RPS19 | ribosomal protein S19 | -0.0240288 |
| WDR43 | WD repeat domain 43 | -0.0237368 |
| IER3 | immediate early response 3 | -0.0236719 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0236702 |
| FGB | fibrinogen beta chain | -0.0235459 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0234539 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0232093 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.023185 |
| TNPO1 | transportin 1 | -0.0231628 |
| MKI67 | marker of proliferation Ki-67 | -0.0231358 |
| ANXA2 | annexin A2 | -0.0230057 |
| PFKP | phosphofructokinase, platelet | -0.0229319 |
| RHOA | ras homolog family member A | -0.0228469 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0224307 |
| THBS1 | thrombospondin 1 | -0.0222722 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0222006 |
| RPS23 | ribosomal protein S23 | -0.0221904 |
| ZNF804A | zinc finger protein 804A | -0.0220498 |
| PARK7 | parkinson protein 7 | -0.0220158 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.021759 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0213989 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.021258 |
| KLF6 | Kruppel-like factor 6 | -0.0209632 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0209589 |
| RPL36 | ribosomal protein L36 | -0.0209324 |
| RPS5 | ribosomal protein S5 | -0.0208947 |
| RPL38 | ribosomal protein L38 | -0.0208821 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0208114 |
| RPL23 | ribosomal protein L23 | -0.0206686 |
| RPS16 | ribosomal protein S16 | -0.0205847 |
| NRG1 | neuregulin 1 | -0.0203983 |
