| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10191 |
| PRKCA | protein kinase C, alpha | 0.101001 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0751847 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0723814 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0695752 |
| MYOF | myoferlin | 0.0679149 |
| SMAD3 | SMAD family member 3 | 0.0669926 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0661035 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0652055 |
| GPC6 | glypican 6 | 0.0634967 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0631267 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0616434 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0598084 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0560882 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.055803 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0556939 |
| EGFR | epidermal growth factor receptor | 0.0551143 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0536589 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0533491 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0525074 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0505343 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0502881 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0493833 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0489804 |
| PDE10A | phosphodiesterase 10A | 0.0475718 |
| CDK13 | cyclin-dependent kinase 13 | 0.0475131 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.046911 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0452659 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.045027 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0448842 |
| CADM1 | cell adhesion molecule 1 | 0.0441261 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0427864 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0427674 |
| CTBP2 | C-terminal binding protein 2 | 0.0425627 |
| AHI1 | Abelson helper integration site 1 | 0.0422864 |
| TXNRD1 | thioredoxin reductase 1 | 0.042195 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0414298 |
| DIAPH1 | diaphanous-related formin 1 | 0.0412847 |
| MACROD2 | MACRO domain containing 2 | 0.040531 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0400966 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0400485 |
| USP25 | ubiquitin specific peptidase 25 | 0.0400237 |
| FLNB | filamin B, beta | 0.0397574 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0393548 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0392333 |
| WTAP | Wilms tumor 1 associated protein | 0.0389766 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0389736 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0388904 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0388277 |
| COG5 | component of oligomeric golgi complex 5 | 0.0386598 |
| FRMD5 | FERM domain containing 5 | 0.0385056 |
| CYTH3 | cytohesin 3 | 0.0381626 |
| FAT1 | FAT atypical cadherin 1 | 0.0381353 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0375726 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0375267 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0373575 |
| ZNF292 | zinc finger protein 292 | 0.037173 |
| DSCAM | Down syndrome cell adhesion molecule | 0.037092 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0369273 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0366435 |
| NABP1 | nucleic acid binding protein 1 | 0.035971 |
| GNAS | GNAS complex locus | 0.0359087 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0358682 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0358292 |
| DGKH | diacylglycerol kinase, eta | 0.0355898 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0354415 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0353385 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0352994 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0352182 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0352042 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0350567 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.034976 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0346921 |
| LAMA4 | laminin, alpha 4 | 0.0344331 |
| PAPOLA | poly(A) polymerase alpha | 0.034277 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0339303 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0338051 |
| ACTG1 | actin gamma 1 | 0.0337862 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0334844 |
| CREBBP | CREB binding protein | 0.0333976 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0333607 |
| RNF130 | ring finger protein 130 | 0.0332146 |
| SEPTIN9 | septin 9 | 0.0330647 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.032481 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.032342 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0323194 |
| YLPM1 | YLP motif containing 1 | 0.0321508 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.03212 |
| FAM13A | family with sequence similarity 13, member A | 0.0321097 |
| FHIT | fragile histidine triad | 0.0316649 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0315523 |
| INTS6 | integrator complex subunit 6 | 0.0314425 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0313921 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0313604 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0313115 |
| AFTPH | aftiphilin | 0.0312722 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0312014 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0311932 |
| CD44 | CD44 molecule (Indian blood group) | 0.031016 |
| JAK1 | Janus kinase 1 | 0.03081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.119636 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.103402 |
| GRB10 | growth factor receptor-bound protein 10 | -0.102079 |
| ATOSA | atos homolog A | -0.0941572 |
| FTL | ferritin, light polypeptide | -0.0926462 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0697927 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0684032 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0671046 |
| MXD1 | MAX dimerization protein 1 | -0.0653135 |
| NDRG1 | N-myc downstream regulated 1 | -0.0646023 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0639242 |
| RIGI | RNA sensor RIG-I | -0.0634449 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0630043 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0628438 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0594483 |
| ABI1 | abl-interactor 1 | -0.0563216 |
| GLCCI1 | glucocorticoid induced 1 | -0.0560668 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0553027 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0536765 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0532312 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0523117 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.048882 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0487882 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0483127 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0480335 |
| NEMF | nuclear export mediator factor | -0.0476907 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0471094 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0469188 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0461449 |
| LSAMP | limbic system-associated membrane protein | -0.045894 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0457491 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0455558 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0451469 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0442707 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0437996 |
| SEPTIN7 | septin 7 | -0.0436257 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0431903 |
| KYNU | kynureninase | -0.0429178 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.042178 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0421422 |
| MED13L | mediator complex subunit 13-like | -0.0412573 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0411058 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0406856 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0406459 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0404248 |
| OSMR | oncostatin M receptor | -0.0402443 |
| TMEM165 | transmembrane protein 165 | -0.0401511 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0398011 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0395795 |
| S100A9 | S100 calcium binding protein A9 | -0.0395649 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0391408 |
| SH3D19 | SH3 domain containing 19 | -0.0389401 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0389055 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0387758 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0385733 |
| RBM47 | RNA binding motif protein 47 | -0.0384402 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.038312 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0382652 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | -0.0378371 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0375735 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0374879 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0374872 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0374504 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0370609 |
| RPL35A | ribosomal protein L35a | -0.0369547 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0368338 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0367496 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0365079 |
| TUT4 | terminal uridylyl transferase 4 | -0.036076 |
| TCERG1 | transcription elongation regulator 1 | -0.0360012 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0358622 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0356894 |
| TAOK3 | TAO kinase 3 | -0.0356768 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.035234 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0346487 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0342905 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0339511 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0337354 |
| RAB2A | RAB2A, member RAS oncogene family | -0.033325 |
| TPD52 | tumor protein D52 | -0.0331343 |
| ZNF638 | zinc finger protein 638 | -0.0330114 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0329611 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0329181 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0328669 |
| IL6ST | interleukin 6 signal transducer | -0.032791 |
| FAM107B | family with sequence similarity 107, member B | -0.0326869 |
| FBXO34 | F-box protein 34 | -0.0325493 |
| KRT17 | keratin 17, type I | -0.0324528 |
| NPTN | neuroplastin | -0.0323652 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0322181 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0319218 |
| REPS1 | RALBP1 associated Eps domain containing 1 | -0.0316964 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.0316869 |
| CD2AP | CD2-associated protein | -0.0315906 |
| HLA-B | major histocompatibility complex, class I, B | -0.0314341 |
| KIF13B | kinesin family member 13B | -0.031374 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0312098 |
| RLF | rearranged L-myc fusion | -0.0310859 |
| HLA-A | major histocompatibility complex, class I, A | -0.0310341 |
| CCDC88A | coiled-coil domain containing 88A | -0.0308513 |
