| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.149066 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0989227 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0527036 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0525751 |
| HLA-B | major histocompatibility complex, class I, B | 0.04499 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0440552 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0425322 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0420511 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0418423 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0416366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0403031 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0387907 |
| RPS3 | ribosomal protein S3 | 0.0369443 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0346866 |
| PRELID2 | PRELI domain containing 2 | 0.0324331 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0283832 |
| ENO1 | enolase 1, (alpha) | 0.027731 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0276276 |
| RPL37 | ribosomal protein L37 | 0.0275947 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0275407 |
| YBX3 | Y box binding protein 3 | 0.0266027 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0248919 |
| RPL11 | ribosomal protein L11 | 0.0231014 |
| TRIM9 | tripartite motif containing 9 | 0.0217738 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0216217 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0211834 |
| MT2A | metallothionein 2A | 0.0205995 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0203356 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0200845 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0196244 |
| SET | SET nuclear proto-oncogene | 0.0193754 |
| RPL37A | ribosomal protein L37a | 0.0191293 |
| DSPP | dentin sialophosphoprotein | 0.0187768 |
| FAM13A | family with sequence similarity 13, member A | 0.0179964 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0172718 |
| HYOU1 | hypoxia up-regulated 1 | 0.0169803 |
| ANGPTL4 | angiopoietin-like 4 | 0.0167246 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0159936 |
| GOLGB1 | golgin B1 | 0.0156145 |
| ATXN1 | ataxin 1 | 0.0152901 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0152413 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0150523 |
| RPS8 | ribosomal protein S8 | 0.0149082 |
| RPS12 | ribosomal protein S12 | 0.014582 |
| B2M | beta-2-microglobulin | 0.0145379 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0144888 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0143513 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0141743 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0140969 |
| RPL7A | ribosomal protein L7a | 0.014022 |
| MCL1 | myeloid cell leukemia 1 | 0.0139835 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0139 |
| PRKCE | protein kinase C, epsilon | 0.0137881 |
| NDRG1 | N-myc downstream regulated 1 | 0.0135927 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0135038 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0134855 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0134086 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0132478 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0131957 |
| RPS17 | ribosomal protein S17 | 0.0131829 |
| RPL9 | ribosomal protein L9 | 0.0127761 |
| USP47 | ubiquitin specific peptidase 47 | 0.0126687 |
| RPL27 | ribosomal protein L27 | 0.0126466 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0124274 |
| MSN | moesin | 0.0124075 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0123676 |
| ASPH | aspartate beta-hydroxylase | 0.0122619 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0121879 |
| RPL26 | ribosomal protein L26 | 0.0121869 |
| DIAPH2 | diaphanous-related formin 2 | 0.0121763 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0120983 |
| MXI1 | MAX interactor 1, dimerization protein | 0.01207 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0120652 |
| ARFGEF3 | ARFGEF family member 3 | 0.0120542 |
| ANXA1 | annexin A1 | 0.0120209 |
| RPL7 | ribosomal protein L7 | 0.0119926 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0119185 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0118892 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0118306 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0117692 |
| H2AC6 | H2A clustered histone 6 | 0.011689 |
| RPS6 | ribosomal protein S6 | 0.0116507 |
| RYR3 | ryanodine receptor 3 | 0.0116372 |
| FMN1 | formin 1 | 0.0116278 |
| NGLY1 | N-glycanase 1 | 0.0116083 |
| MANBA | mannosidase, beta A, lysosomal | 0.0115814 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0114203 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0111419 |
| RPL10A | ribosomal protein L10a | 0.0110459 |
| HLA-E | major histocompatibility complex, class I, E | 0.0109286 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0109017 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.0108388 |
| FMNL2 | formin-like 2 | 0.010822 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0107652 |
| GPC6 | glypican 6 | 0.0106963 |
| HLA-A | major histocompatibility complex, class I, A | 0.0106136 |
| OPTN | optineurin | 0.0105665 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0103962 |
| FN1 | fibronectin 1 | 0.0103325 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0103119 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.136314 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0934913 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0910433 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0693799 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.06323 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0614531 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0572383 |
| EGR1 | early growth response 1 | -0.0550439 |
| MKI67 | marker of proliferation Ki-67 | -0.0520608 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0519407 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0509902 |
| RAD51B | RAD51 paralog B | -0.0504643 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0490172 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0486373 |
| GRAMD1B | GRAM domain containing 1B | -0.0470156 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0451818 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0437902 |
| TMSB10 | thymosin beta 10 | -0.0437186 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0424309 |
| VCL | vinculin | -0.042134 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0408603 |
| FBXO11 | F-box protein 11 | -0.0402543 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0395758 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0383393 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0381635 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0373827 |
| RBM39 | RNA binding motif protein 39 | -0.0373816 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0372059 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0371399 |
| AHNAK | AHNAK nucleoprotein | -0.0366257 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0362042 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0358195 |
| SMAD3 | SMAD family member 3 | -0.0354562 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0354393 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0351574 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0348751 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.034694 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.03381 |
| PTMA | prothymosin, alpha | -0.0337963 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0329162 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0326293 |
| PHIP | pleckstrin homology domain interacting protein | -0.0325117 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0322695 |
| RPL23 | ribosomal protein L23 | -0.0322318 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0319357 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0317786 |
| EXOC4 | exocyst complex component 4 | -0.0317517 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0310442 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0309558 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0305316 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0299843 |
| MED13L | mediator complex subunit 13-like | -0.0294762 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0294174 |
| XPO1 | exportin 1 | -0.0292037 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0291634 |
| NABP1 | nucleic acid binding protein 1 | -0.0288222 |
| RRM2 | ribonucleotide reductase M2 | -0.028704 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0279548 |
| H1-0 | H1.0 linker histone | -0.0279411 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0279246 |
| KIAA1328 | KIAA1328 | -0.0277729 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0276466 |
| RASAL2 | RAS protein activator like 2 | -0.0273143 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.027289 |
| SPAG9 | sperm associated antigen 9 | -0.0272601 |
| CLTC | clathrin, heavy chain (Hc) | -0.0272102 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0271497 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0268797 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0262602 |
| MORF4L2 | mortality factor 4 like 2 | -0.0262257 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0261448 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0257595 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0253709 |
| FUS | FUS RNA binding protein | -0.0253361 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0252863 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.025266 |
| CDK17 | cyclin-dependent kinase 17 | -0.0252185 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0249766 |
| RTN4 | reticulon 4 | -0.0249721 |
| DIAPH3 | diaphanous-related formin 3 | -0.0249398 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0248066 |
| TNPO3 | transportin 3 | -0.0247275 |
| KLF6 | Kruppel-like factor 6 | -0.0246749 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0245575 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0245248 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0244592 |
| TAOK1 | TAO kinase 1 | -0.0243811 |
| ZFR | zinc finger RNA binding protein | -0.02437 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0243647 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0243554 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0243291 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0243047 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.023911 |
| WDR70 | WD repeat domain 70 | -0.0238015 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0237258 |
| ATF6 | activating transcription factor 6 | -0.0232914 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0232642 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.023206 |
| WASF2 | WAS protein family, member 2 | -0.0231545 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0231095 |
