| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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165 genes differentially expressed following the Triclosan_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.24254 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.202222 |
| EXT1 | exostosin glycosyltransferase 1 | 0.145707 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.125479 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.116926 |
| NDRG1 | N-myc downstream regulated 1 | 0.113551 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.112281 |
| ASPH | aspartate beta-hydroxylase | 0.101968 |
| MT2A | metallothionein 2A | 0.101428 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0997101 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.094613 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0921588 |
| HLA-B | major histocompatibility complex, class I, B | 0.0917962 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0839693 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0814356 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0793619 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0786151 |
| PTK2 | protein tyrosine kinase 2 | 0.0774029 |
| FTL | ferritin, light polypeptide | 0.0766242 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0663539 |
| B2M | beta-2-microglobulin | 0.0657695 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0657113 |
| GOLGB1 | golgin B1 | 0.0632152 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0610623 |
| NABP1 | nucleic acid binding protein 1 | 0.0603508 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0583652 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0579948 |
| YAP1 | Yes-associated protein 1 | 0.0520141 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0516723 |
| PKM | pyruvate kinase, muscle | 0.0501541 |
| KIF5B | kinesin family member 5B | 0.0500581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0487444 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.047383 |
| ZNF292 | zinc finger protein 292 | 0.0431281 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0423 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0421963 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0421625 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0414183 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0390844 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0375906 |
| RORA | RAR-related orphan receptor A | 0.0374611 |
| GPC6 | glypican 6 | 0.0369976 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0369852 |
| GOLGA4 | golgin A4 | 0.035615 |
| USP34 | ubiquitin specific peptidase 34 | 0.0352704 |
| DST | dystonin | 0.0349337 |
| PTMA | prothymosin, alpha | 0.0347161 |
| RIGI | RNA sensor RIG-I | 0.0346425 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.034136 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0339346 |
| ANKRD17 | ankyrin repeat domain 17 | 0.033501 |
| ZNF608 | zinc finger protein 608 | 0.030042 |
| MYO1E | myosin IE | 0.0299915 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.029372 |
| PEG10 | paternally expressed 10 | 0.0292466 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0288948 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0284479 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0249767 |
| CD44 | CD44 molecule (Indian blood group) | 0.0247294 |
| FLNB | filamin B, beta | 0.021478 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0205928 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0196993 |
| JMJD1C | jumonji domain containing 1C | 0.017066 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0170311 |
| PRELID2 | PRELI domain containing 2 | 0.0164587 |
| ARRDC3 | arrestin domain containing 3 | 0.0152642 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0132843 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0125811 |
| GPHN | gephyrin | 0.0116874 |
| ANXA2 | annexin A2 | 0.0110758 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.00995626 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00992182 |
| COL5A2 | collagen, type V, alpha 2 | 0.00958279 |
| PDE10A | phosphodiesterase 10A | 0.00895948 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.00861758 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00754741 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00740574 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00740198 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.00688143 |
| RNF213 | ring finger protein 213 | 0.00661076 |
| RUNX1 | runt-related transcription factor 1 | 0.00593632 |
| NF1 | neurofibromin 1 | 0.00590219 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00371466 |
| LMO7 | LIM domain 7 | 0.00283158 |
| CADM2 | cell adhesion molecule 2 | 0.00267434 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 8.85168E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.136413 |
| EGFR | epidermal growth factor receptor | -0.12702 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.122074 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.120734 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.119629 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.116167 |
| ITGA6 | integrin, alpha 6 | -0.115376 |
| COL6A3 | collagen, type VI, alpha 3 | -0.108127 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.103624 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0972383 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0951536 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0866683 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0864542 |
| ATP11A | ATPase, class VI, type 11A | -0.0839083 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0814051 |
| SLTM | SAFB-like, transcription modulator | -0.0776203 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0766031 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0723059 |
| PRKCA | protein kinase C, alpha | -0.0711119 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0701995 |
| EFNA5 | ephrin-A5 | -0.0696977 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0690764 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0667871 |
| CNKSR3 | CNKSR family member 3 | -0.0667625 |
| NOP58 | NOP58 ribonucleoprotein | -0.066589 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0654895 |
| CUX1 | cut-like homeobox 1 | -0.0653354 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0651404 |
| ITGAV | integrin, alpha V | -0.0633166 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0609809 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0606762 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0594131 |
| ANKRD12 | ankyrin repeat domain 12 | -0.050798 |
| HMGA2 | high mobility group AT-hook 2 | -0.0491505 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.048879 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0465723 |
| SBF2 | SET binding factor 2 | -0.0464955 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0453063 |
| INHBA | inhibin, beta A | -0.0438638 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0435022 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0419455 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0418224 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0403966 |
| VIM | vimentin | -0.0402847 |
| ANO6 | anoctamin 6 | -0.0390282 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0390007 |
| VCL | vinculin | -0.038459 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0353596 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0322559 |
| SMYD3 | SET and MYND domain containing 3 | -0.0322046 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0318233 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0317055 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0297459 |
| MED13L | mediator complex subunit 13-like | -0.0285149 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0256075 |
| CDH13 | cadherin 13 | -0.0254242 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0248521 |
| ENO1 | enolase 1, (alpha) | -0.0245354 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0232924 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0211438 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0206793 |
| PARD3 | par-3 family cell polarity regulator | -0.0201027 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0200899 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0176375 |
| RPS6 | ribosomal protein S6 | -0.0176123 |
| ATXN1 | ataxin 1 | -0.0170906 |
| TMSB10 | thymosin beta 10 | -0.0169262 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0165278 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0159577 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0131542 |
| RBM39 | RNA binding motif protein 39 | -0.0115969 |
| FOXP1 | forkhead box P1 | -0.00890452 |
| FN1 | fibronectin 1 | -0.00801311 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00771461 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.00727886 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00427785 |
| CCNI | cyclin I | -0.0036119 |
| MYOF | myoferlin | -0.00336315 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -6.3461E-5 |
