| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0463548 |
| CENPF | centromere protein F, 350/400kDa | 0.0462468 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0348395 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303122 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0284714 |
| CENPE | centromere protein E, 312kDa | 0.0230106 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0227821 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0215706 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0204248 |
| CFL2 | cofilin 2 (muscle) | 0.0195716 |
| RPS2 | ribosomal protein S2 | 0.0189388 |
| STMN1 | stathmin 1 | 0.0178687 |
| SET | SET nuclear proto-oncogene | 0.0177214 |
| DSTN | destrin (actin depolymerizing factor) | 0.0176076 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0174736 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0172159 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0163201 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0162945 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0161477 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0160827 |
| CBX3 | chromobox homolog 3 | 0.0158795 |
| ZNF638 | zinc finger protein 638 | 0.0156045 |
| PCM1 | pericentriolar material 1 | 0.015158 |
| MYO9A | myosin IXA | 0.0150849 |
| RPL11 | ribosomal protein L11 | 0.0150203 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0150108 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0147723 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.014623 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0141468 |
| DRC8 | dynein regulatory complex subunit 8 | 0.0140338 |
| UBXN4 | UBX domain protein 4 | 0.0140328 |
| SARS1 | seryl-tRNA synthetase 1 | 0.0138351 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0137954 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0136734 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0132122 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.0131874 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0130676 |
| BRD2 | bromodomain containing 2 | 0.0130467 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0129559 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0129268 |
| RPS3 | ribosomal protein S3 | 0.0128656 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.012837 |
| CLIC4 | chloride intracellular channel 4 | 0.01273 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0126799 |
| FAT1 | FAT atypical cadherin 1 | 0.0123265 |
| TRIQK | triple QxxK/R motif containing | 0.01231 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0122949 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.012286 |
| OXR1 | oxidation resistance 1 | 0.0122625 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0120622 |
| HMGB2 | high mobility group box 2 | 0.0120603 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0120463 |
| CDK6 | cyclin-dependent kinase 6 | 0.0120361 |
| INO80 | INO80 complex subunit | 0.0119923 |
| RRP1B | ribosomal RNA processing 1B | 0.0119762 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0119528 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0118571 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | 0.011787 |
| FMNL2 | formin-like 2 | 0.011776 |
| DOK6 | docking protein 6 | 0.0116658 |
| RPL7A | ribosomal protein L7a | 0.0115438 |
| ATM | ATM serine/threonine kinase | 0.0115414 |
| FOXN3 | forkhead box N3 | 0.0114328 |
| KNL1 | kinetochore scaffold 1 | 0.011419 |
| NAV1 | neuron navigator 1 | 0.0113619 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0113472 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0113233 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0113049 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0112374 |
| CCNA2 | cyclin A2 | 0.0112225 |
| PCBP2 | poly(rC) binding protein 2 | 0.0111593 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0110739 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0110636 |
| REST | RE1-silencing transcription factor | 0.011024 |
| STK39 | serine threonine kinase 39 | 0.0109882 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0109078 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0109066 |
| BMERB1 | bMERB domain containing 1 | 0.0108775 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0107595 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0107202 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0106865 |
| ERBIN | erbb2 interacting protein | 0.0106837 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0106433 |
| RPL26 | ribosomal protein L26 | 0.0105964 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.010587 |
| FOXO1 | forkhead box O1 | 0.010538 |
| PDE8A | phosphodiesterase 8A | 0.0104838 |
| WASHC5 | WASH complex subunit 5 | 0.0103693 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0103635 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0103592 |
| MANBA | mannosidase, beta A, lysosomal | 0.0103263 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0103157 |
| USP26 | ubiquitin specific peptidase 26 | 0.0102787 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0102647 |
| NBAS | neuroblastoma amplified sequence | 0.0102014 |
| EGFR | epidermal growth factor receptor | 0.0102014 |
| EEA1 | early endosome antigen 1 | 0.0101728 |
| MKI67 | marker of proliferation Ki-67 | 0.0101486 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0101383 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.01012 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.185662 |
| COL11A1 | collagen, type XI, alpha 1 | -0.175153 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.165443 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.145221 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.119137 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.100998 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0838008 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0787672 |
| PCDH9 | protocadherin 9 | -0.0778863 |
| PLPP1 | phospholipid phosphatase 1 | -0.0766098 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0750012 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0738583 |
| COL5A2 | collagen, type V, alpha 2 | -0.07069 |
| COL3A1 | collagen, type III, alpha 1 | -0.0676048 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0667711 |
| TENM3 | teneurin transmembrane protein 3 | -0.0621816 |
| GPC3 | glypican 3 | -0.0615308 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0615067 |
| VIM | vimentin | -0.061453 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0600992 |
| CADM2 | cell adhesion molecule 2 | -0.058497 |
| TSC22D2 | TSC22 domain family, member 2 | -0.051726 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0504188 |
| HDAC9 | histone deacetylase 9 | -0.0495104 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.048842 |
| ITGAV | integrin, alpha V | -0.0488201 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0483918 |
| NRG1 | neuregulin 1 | -0.0483592 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0478055 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0467995 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0449129 |
| RBM20 | RNA binding motif protein 20 | -0.0443971 |
| FAM171B | family with sequence similarity 171, member B | -0.0428021 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0418315 |
| MEIS2 | Meis homeobox 2 | -0.0416559 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0416505 |
| COL1A2 | collagen, type I, alpha 2 | -0.0415698 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0413069 |
| ANK2 | ankyrin 2, neuronal | -0.0411186 |
| PHIP | pleckstrin homology domain interacting protein | -0.0403883 |
| AHNAK | AHNAK nucleoprotein | -0.0395476 |
| HMGA2 | high mobility group AT-hook 2 | -0.0391571 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0390399 |
| SHROOM3 | shroom family member 3 | -0.0389705 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0389067 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0384559 |
| EMP1 | epithelial membrane protein 1 | -0.0381848 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0380318 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0378418 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0370758 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0364479 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.035402 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0353593 |
| NHSL1 | NHS-like 1 | -0.0347701 |
| TOX | thymocyte selection-associated high mobility group box | -0.0338699 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0332999 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0327203 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0323183 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0322872 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0321489 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0316537 |
| PEG10 | paternally expressed 10 | -0.0312476 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0310228 |
| PCDH7 | protocadherin 7 | -0.0306019 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0297748 |
| PHF21A | PHD finger protein 21A | -0.029722 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0291186 |
| PTMA | prothymosin, alpha | -0.0290067 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0283999 |
| MAP4 | microtubule-associated protein 4 | -0.028353 |
| ZNF217 | zinc finger protein 217 | -0.0282814 |
| SFRP4 | secreted frizzled-related protein 4 | -0.028272 |
| SRP54 | signal recognition particle 54kDa | -0.0282572 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0277481 |
| PDGFC | platelet derived growth factor C | -0.0270354 |
| ATXN2 | ataxin 2 | -0.0268177 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0265083 |
| PTK2 | protein tyrosine kinase 2 | -0.0264031 |
| RPS16 | ribosomal protein S16 | -0.0261455 |
| THBS1 | thrombospondin 1 | -0.0255746 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.025469 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0253648 |
| SRPK2 | SRSF protein kinase 2 | -0.0253368 |
| RAB31 | RAB31, member RAS oncogene family | -0.0253104 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0250494 |
| SIK2 | salt-inducible kinase 2 | -0.0248073 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0247935 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0245427 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0245375 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0242907 |
| UPP1 | uridine phosphorylase 1 | -0.0242834 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.024232 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0242136 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.024009 |
| DENND5B | DENN/MADD domain containing 5B | -0.0239414 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0239004 |
| DENND1A | DENN/MADD domain containing 1A | -0.0238339 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0236974 |
| LRRC4C | leucine rich repeat containing 4C | -0.0236586 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0235505 |
