| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Triclosan_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.114501 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0768438 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0762065 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0750363 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0630897 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0584034 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0566058 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0541946 |
| NAV2 | neuron navigator 2 | 0.0514017 |
| PRELID2 | PRELI domain containing 2 | 0.0487223 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0481297 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.047806 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0460499 |
| HELZ | helicase with zinc finger | 0.0398948 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0391132 |
| INTS6 | integrator complex subunit 6 | 0.0385607 |
| PLIN2 | perilipin 2 | 0.0381078 |
| GOLGA4 | golgin A4 | 0.0375994 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0358467 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0348511 |
| FNIP1 | folliculin interacting protein 1 | 0.0347637 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.034279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0335284 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0330164 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0329894 |
| FMNL2 | formin-like 2 | 0.032343 |
| OPTN | optineurin | 0.0321504 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0298016 |
| RPS6 | ribosomal protein S6 | 0.0296124 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0289301 |
| CANX | calnexin | 0.0288516 |
| FBXO32 | F-box protein 32 | 0.0283861 |
| MMP12 | matrix metallopeptidase 12 | 0.0280188 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0276296 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0275945 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0272411 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0269441 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0262288 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0261828 |
| ASPH | aspartate beta-hydroxylase | 0.0260566 |
| DST | dystonin | 0.0259534 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0259055 |
| STAG2 | stromal antigen 2 | 0.025761 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0257188 |
| CADM1 | cell adhesion molecule 1 | 0.0250356 |
| PCBP2 | poly(rC) binding protein 2 | 0.0249292 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0247864 |
| ZNF292 | zinc finger protein 292 | 0.0247831 |
| RPL7A | ribosomal protein L7a | 0.0246155 |
| VEGFA | vascular endothelial growth factor A | 0.0245991 |
| ENO1 | enolase 1, (alpha) | 0.0245564 |
| SQSTM1 | sequestosome 1 | 0.0237143 |
| RND3 | Rho family GTPase 3 | 0.023638 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0234858 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.023247 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0231588 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0229082 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0228743 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0228356 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.022328 |
| HMGA2 | high mobility group AT-hook 2 | 0.0219825 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0219296 |
| PGM3 | phosphoglucomutase 3 | 0.0219167 |
| ZNF638 | zinc finger protein 638 | 0.0217496 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0217408 |
| EPHA6 | EPH receptor A6 | 0.0216444 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.021585 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0214964 |
| CDH13 | cadherin 13 | 0.0210998 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0208831 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.020487 |
| FAM13A | family with sequence similarity 13, member A | 0.0203692 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0203299 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0203257 |
| DUSP10 | dual specificity phosphatase 10 | 0.0202391 |
| ANXA1 | annexin A1 | 0.0200842 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0200842 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0196016 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0195568 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0194835 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0194799 |
| IRS2 | insulin receptor substrate 2 | 0.0192375 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0191896 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0191334 |
| RYBP | RING1 and YY1 binding protein | 0.0190852 |
| BRD2 | bromodomain containing 2 | 0.0189595 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0188836 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0186174 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0184093 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0183948 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0183098 |
| PHF3 | PHD finger protein 3 | 0.0182246 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.018136 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0176842 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.017672 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.017611 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0175333 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0174774 |
| OGA | O-GlcNAcase | 0.0171891 |
| YAP1 | Yes-associated protein 1 | 0.0170732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.23018 |
| VCL | vinculin | -0.146793 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.140473 |
| FRMD4A | FERM domain containing 4A | -0.126622 |
| BICC1 | BicC family RNA binding protein 1 | -0.118124 |
| GLIS3 | GLIS family zinc finger 3 | -0.112603 |
| VIM | vimentin | -0.106774 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.106324 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.100346 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0925434 |
| SMAD3 | SMAD family member 3 | -0.0789139 |
| HLA-B | major histocompatibility complex, class I, B | -0.0782659 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0770793 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0752931 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0751139 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0722166 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0719145 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.061272 |
| TMSB10 | thymosin beta 10 | -0.0580926 |
| CD44 | CD44 molecule (Indian blood group) | -0.057849 |
| OSMR | oncostatin M receptor | -0.0577213 |
| RTN4 | reticulon 4 | -0.0564603 |
| AHNAK | AHNAK nucleoprotein | -0.0562377 |
| THBS1 | thrombospondin 1 | -0.0540301 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.04947 |
| ANXA2 | annexin A2 | -0.0485153 |
| EGR1 | early growth response 1 | -0.0481703 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.046592 |
| PALLD | palladin, cytoskeletal associated protein | -0.0463705 |
| CDCP1 | CUB domain containing protein 1 | -0.0459853 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0458123 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0440766 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0436586 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0427235 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0415624 |
| NAV1 | neuron navigator 1 | -0.0403201 |
| NABP1 | nucleic acid binding protein 1 | -0.0385066 |
| KLF6 | Kruppel-like factor 6 | -0.0382207 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0369591 |
| RRBP1 | ribosome binding protein 1 | -0.0369232 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0367554 |
| MKI67 | marker of proliferation Ki-67 | -0.0367289 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0366655 |
| PDE10A | phosphodiesterase 10A | -0.0366511 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0363504 |
| TNNC1 | troponin C type 1 (slow) | -0.0360274 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0340776 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0334997 |
| VCAN | versican | -0.0334029 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0332034 |
| PGK1 | phosphoglycerate kinase 1 | -0.0330029 |
| LOXL2 | lysyl oxidase-like 2 | -0.0328202 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0323072 |
| SBF2 | SET binding factor 2 | -0.03119 |
| THBS2 | thrombospondin 2 | -0.0308437 |
| RUNX2 | runt-related transcription factor 2 | -0.0305742 |
| SYNJ2 | synaptojanin 2 | -0.0301909 |
| KPNB1 | karyopherin (importin) beta 1 | -0.029886 |
| PLPP6 | phospholipid phosphatase 6 | -0.0297424 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0294239 |
| FN1 | fibronectin 1 | -0.028914 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0287276 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0282218 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0282064 |
| MAP1B | microtubule-associated protein 1B | -0.0280163 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0277497 |
| TPM4 | tropomyosin 4 | -0.027475 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0274554 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0273774 |
| RIGI | RNA sensor RIG-I | -0.0269952 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0265986 |
| FRMD5 | FERM domain containing 5 | -0.0265876 |
| EHBP1 | EH domain binding protein 1 | -0.0265794 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0263954 |
| ACTN1 | actinin, alpha 1 | -0.0259088 |
| MT2A | metallothionein 2A | -0.0258619 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0257888 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0254156 |
| MAP4 | microtubule-associated protein 4 | -0.025321 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0252537 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0251929 |
| TMEM41B | transmembrane protein 41B | -0.025036 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0247932 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0247479 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.024695 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0245157 |
| FAM20C | family with sequence similarity 20, member C | -0.0245019 |
| CDK17 | cyclin-dependent kinase 17 | -0.0243562 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0242464 |
| RAI14 | retinoic acid induced 14 | -0.0241272 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0240603 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0237752 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0237378 |
| AFDN | afadin, adherens junction formation factor | -0.0236103 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0235792 |
| TXNRD1 | thioredoxin reductase 1 | -0.0231056 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0229535 |
| TNS3 | tensin 3 | -0.0227245 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0225518 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0220553 |
