| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Triclosan perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Triclosan_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.200024 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0782396 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.073885 |
| FAM13A | family with sequence similarity 13, member A | 0.0692963 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0687559 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0671805 |
| STC1 | stanniocalcin 1 | 0.0586714 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0461467 |
| ARRDC3 | arrestin domain containing 3 | 0.0456764 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0420571 |
| CDH13 | cadherin 13 | 0.0418401 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0397639 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0380463 |
| MTDH | metadherin | 0.0363978 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0362504 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0361917 |
| COPA | coatomer protein complex, subunit alpha | 0.0358166 |
| RAB1A | RAB1A, member RAS oncogene family | 0.035619 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0334534 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0310582 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0303953 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0299052 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0292057 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0291714 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0291008 |
| ADM | adrenomedullin | 0.0285854 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0279237 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0276031 |
| YME1L1 | YME1-like 1 ATPase | 0.0270189 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0267584 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0257982 |
| YTHDC1 | YTH domain containing 1 | 0.02563 |
| HM13 | histocompatibility (minor) 13 | 0.0251373 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0251191 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0246805 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0244807 |
| RND3 | Rho family GTPase 3 | 0.0244765 |
| ZNF395 | zinc finger protein 395 | 0.0238086 |
| PTGES2 | prostaglandin E synthase 2 | 0.0237343 |
| RINT1 | RAD50 interactor 1 | 0.0232637 |
| SERINC3 | serine incorporator 3 | 0.0229579 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0228994 |
| VIRMA | vir like m6A methyltransferase associated | 0.0227821 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0227038 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0226993 |
| GOLGA4 | golgin A4 | 0.0226363 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0225905 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.0225476 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0225344 |
| OPTN | optineurin | 0.0224964 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0223494 |
| ENO1 | enolase 1, (alpha) | 0.0221291 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0219843 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.0219156 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0214941 |
| COG5 | component of oligomeric golgi complex 5 | 0.0213852 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.021183 |
| TMEM87A | transmembrane protein 87A | 0.0211372 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0209282 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0207728 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.0207641 |
| TFG | TRK-fused gene | 0.02074 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0205036 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0204795 |
| MLEC | malectin | 0.020469 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0203063 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0202063 |
| INSIG2 | insulin induced gene 2 | 0.0201538 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0200826 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0199987 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0198345 |
| CCNT2 | cyclin T2 | 0.0196938 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0196026 |
| RLF | rearranged L-myc fusion | 0.0192681 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0190891 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0190681 |
| SRP72 | signal recognition particle 72kDa | 0.018986 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0189317 |
| GOLGB1 | golgin B1 | 0.0189149 |
| WDR43 | WD repeat domain 43 | 0.0188138 |
| PMM2 | phosphomannomutase 2 | 0.0187853 |
| SEC24A | SEC24 family member A | 0.0186318 |
| USP37 | ubiquitin specific peptidase 37 | 0.0185472 |
| RTCB | RNA 2',3'-cyclic phosphate and 5'-OH ligase | 0.0180713 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0180703 |
| MMP12 | matrix metallopeptidase 12 | 0.0180408 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0180261 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.017955 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0179212 |
| MYADM | myeloid-associated differentiation marker | 0.0176196 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0176074 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0173874 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0172196 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0172006 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 | 0.017193 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.017119 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0171013 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0170855 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.017076 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0169344 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.146386 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.133902 |
| VIM | vimentin | -0.123267 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119509 |
| HLA-B | major histocompatibility complex, class I, B | -0.101403 |
| COL1A2 | collagen, type I, alpha 2 | -0.0919962 |
| COL1A1 | collagen, type I, alpha 1 | -0.0739883 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.071473 |
| CALD1 | caldesmon 1 | -0.0662321 |
| ANXA2 | annexin A2 | -0.063359 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0621645 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0584521 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0581758 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0552779 |
| CD44 | CD44 molecule (Indian blood group) | -0.0534185 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0509459 |
| PKM | pyruvate kinase, muscle | -0.0488356 |
| EXT1 | exostosin glycosyltransferase 1 | -0.048359 |
| NAV1 | neuron navigator 1 | -0.0467506 |
| GLIS3 | GLIS family zinc finger 3 | -0.0453817 |
| PRSS23 | protease, serine, 23 | -0.045094 |
| DST | dystonin | -0.0437747 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0436864 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0404057 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0403902 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0382584 |
| MED13L | mediator complex subunit 13-like | -0.0380849 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0371951 |
| HLA-C | major histocompatibility complex, class I, C | -0.0370519 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.036753 |
| FRMD4A | FERM domain containing 4A | -0.0356482 |
| TPM4 | tropomyosin 4 | -0.0343701 |
| VCL | vinculin | -0.0343639 |
| FTL | ferritin, light polypeptide | -0.0340687 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0339896 |
| UBC | ubiquitin C | -0.0338694 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0335584 |
| PGK1 | phosphoglycerate kinase 1 | -0.033203 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0322283 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0321986 |
| S100A9 | S100 calcium binding protein A9 | -0.032162 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0320972 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0320362 |
| H3-3B | H3.3 histone B | -0.0319099 |
| STC2 | stanniocalcin 2 | -0.0313072 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0309323 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0307984 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305969 |
| TBCA | tubulin folding cofactor A | -0.0301019 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0300096 |
| S100A6 | S100 calcium binding protein A6 | -0.0298683 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.029668 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0296571 |
| FAT1 | FAT atypical cadherin 1 | -0.0291373 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0288239 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0286787 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.028484 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0283868 |
| PRELID2 | PRELI domain containing 2 | -0.0282266 |
| FN1 | fibronectin 1 | -0.0281733 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0281635 |
| RPL11 | ribosomal protein L11 | -0.0279203 |
| TNPO1 | transportin 1 | -0.027737 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0275861 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.027488 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0271655 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0269667 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0264824 |
| HPCAL1 | hippocalcin-like 1 | -0.0264602 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0262691 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0262444 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0262113 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0261324 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0259445 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0255966 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0255813 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0255578 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0254886 |
| PRKCA | protein kinase C, alpha | -0.0254831 |
| RPS24 | ribosomal protein S24 | -0.0252149 |
| RASAL2 | RAS protein activator like 2 | -0.0249014 |
| RPS6 | ribosomal protein S6 | -0.0248171 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0247734 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0246735 |
| ERBIN | erbb2 interacting protein | -0.0244809 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0244116 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0241447 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0239822 |
| EGR1 | early growth response 1 | -0.0238843 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0238624 |
| ACTN4 | actinin, alpha 4 | -0.0238407 |
| TPM1 | tropomyosin 1 (alpha) | -0.0237784 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0237119 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0236629 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0236294 |
| COL5A1 | collagen, type V, alpha 1 | -0.0236102 |
| SDC4 | syndecan 4 | -0.023445 |
| NRP1 | neuropilin 1 | -0.0233771 |
| MT1X | metallothionein 1X | -0.0232533 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0230056 |