Tricuspid Valve Insufficiency Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A tricuspid valve disease that is characterized by failure of the heart's tricuspid valve to close properly during systole. As a result, with each heart beat, blood is pumped out from the right side of the heart in the opposite direction to normal. (Human Disease Ontology, DOID_4080)
External Link https://www.disgenet.org/browser/0/1/0/C0040961
Similar Terms
Downloads & Tools

Genes

57 genes associated with the disease Tricuspid Valve Insufficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACP3 acid phosphatase 3
ALPK3 alpha-kinase 3
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATRX alpha thalassemia/mental retardation syndrome X-linked
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLIC2 chloride intracellular channel 2
CNTNAP2 contactin associated protein-like 2
COX2
COX7B cytochrome c oxidase subunit VIIb
CRP C-reactive protein, pentraxin-related
DAXX death-domain associated protein
DLL4 delta-like 4 (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DVL3 dishevelled segment polarity protein 3
FBN1 fibrillin 1
FLNA filamin A, alpha
GGTLC1 gamma-glutamyltransferase light chain 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCCS holocytochrome c synthase
HEPHL1 hephaestin-like 1
HMOX1 heme oxygenase 1
HP haptoglobin
IFNG interferon, gamma
IL1B interleukin 1, beta
IL6 interleukin 6
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like
LPA lipoprotein, Lp(a)
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MRPS30 mitochondrial ribosomal protein S30
MTPAP mitochondrial poly(A) polymerase
MUC16 mucin 16, cell surface associated
MYH11 myosin, heavy chain 11, smooth muscle
NCAPG2 non-SMC condensin II complex, subunit G2
NDE1 nudE neurodevelopment protein 1
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
NONO non-POU domain containing, octamer-binding
NRXN1 neurexin 1
PAEP progestagen-associated endometrial protein
PAPOLA poly(A) polymerase alpha
PDAP1 PDGFA associated protein 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PREP prolyl endopeptidase
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAD21 RAD21 homolog (S. pombe)
REG3A regenerating islet-derived 3 alpha
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SRSF2 serine/arginine-rich splicing factor 2
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TUSC2 tumor suppressor candidate 2