Trifluoperazine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. (Chemical Entities of Biological Interest Ontology, CHEBI_45951)
External Link http://ctdbase.org/detail.go?type=chem&acc=D014268
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Genes

28 genes/proteins interacting with the chemical Trifluoperazine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACHE acetylcholinesterase (Yt blood group)
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IL12B interleukin 12B
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYL9 myosin, light chain 9, regulatory
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARP1 poly (ADP-ribose) polymerase 1
PRL prolactin
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4